Results 111 to 120 of about 43,360 (234)

Development and Characterisation of a Starvation‐ and Exercise‐Induced Murine Model of Microvesicular Steatosis Relevant to Anorexia Nervosa

open access: yesLiver International Communications, Volume 7, Issue 1, March 2026.
ABSTRACT Anorexia nervosa (AN) leads to severe dietary restriction, low body weight, and in many patients, hepatocellular steatosis. Clinically, hepatic fat in AN is usually macrovesicular, whereas microvesicular steatosis is more often associated with severe starvation and mitochondrial dysfunction.
Michiko Ishii   +9 more
wiley   +1 more source

Changes in Plasma Sphingolipid Metabolites Following Roux‐En‐Y Gastric Bypass in Women With Obesity and Type 2 Diabetes: A Pilot Metabolomic Cohort Study

open access: yesLipids, Volume 61, Issue 2, Page 195-205, March 2026.
ABSTRACT Although sphingolipids are key players in lipotoxicity and metabolic diseases, their response to bariatric surgery and their relation to metabolic improvement remain unclear. This pilot study investigated plasma sphingolipid remodeling after Roux‐en‐Y gastric bypass (RYGB) and its associations with clinical and biochemical markers of ...
Gabriela de Oliveira Lemos   +3 more
wiley   +1 more source

The Role of Food Structure on Fatty Acid Bioaccessibility: A Decade of TIM‐1 Simulated Digestion Studies in Review

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 6, 29 March 2026.
Lipid and food structure determine when and how macro‐ and micronutrients become bioaccessible. This review compares lipid bioaccessibility from engineered emulsions, breast milk, infant formula, and meat and meat mimics, which couples the effect of cooking temperature on lipid bioaccessibility in meat and eggs. ABSTRACT Food structure has emerged as a
Michael A. Rogers, Amanda J. Wright
wiley   +1 more source

Preface to VLDL 2010

open access: yes, 2010
The goal of the Third Very Large Digital Library workshop is to discuss on-going implementations of Digital Libraries, hence to continue on providing researchers, practitioners and application developers with a forum fostering a constructive exchange among all key actors in the field of Very Large Digital Libraries.
Ioannidis Y., Manghi P., Pagano P.
openaire   +1 more source

Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders

open access: yesNeuroprotection, Volume 4, Issue 1, Page 30-47, March 2026.
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan   +5 more
wiley   +1 more source

The MetaboHealth Score Enhances Insulin Resistance Metabotyping for Targeted Fat Loss: The PERSON Study

open access: yesObesity, Volume 34, Issue 3, Page 550-564, March 2026.
ABSTRACT Objective We previously identified distinct muscle and liver insulin resistance (IR) metabotypes in middle‐aged and older adults. The PERSON study showed that a low‐fat, high‐protein, high‐fiber diet benefits the muscle IR group, while a high‐monounsaturated fatty acid diet benefits the liver IR group. We also developed the MetaboHealth score,
Jordi Morwani‐Mangnani   +10 more
wiley   +1 more source

Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT‐1 Trial

open access: yesObesity, Volume 34, Issue 3, Page 608-621, March 2026.
ABSTRACT Objective This prespecified subpopulation analysis aimed to assess the efficacy and safety of once‐weekly tirzepatide versus placebo alongside lifestyle intervention in Japanese adults with obesity or overweight. Methods Data from 102 Japanese adults in the SURMOUNT‐1 trial with BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 and ≥ 1 weight‐related comorbidity ...
Yasushi Ishigaki   +4 more
wiley   +1 more source

Heart failure etiology and lipoprotein subfractions: Insight from the SMARTEX-HF study. [PDF]

open access: yesInt J Cardiol Heart Vasc
Karlsen T   +15 more
europepmc   +1 more source

Obesity on Early Pregnancy and Cardiometabolic Profile on the Preterm Period: A Retrospective Prevalence‐Based Study Among Cameroonian Pregnant Women

open access: yesReproductive, Female and Child Health, Volume 5, Issue 1, March 2026.
ABSTRACT Objectives To assess the prevalence and determinants of early pregnancy obesity (EPO) and its effects on the preterm cardiometabolic profile. Materials and Methods This study was conducted at the antenatal care unit of the Dschang district hospital.
Solange Dabou   +5 more
wiley   +1 more source

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