Results 111 to 120 of about 43,360 (234)
ABSTRACT Anorexia nervosa (AN) leads to severe dietary restriction, low body weight, and in many patients, hepatocellular steatosis. Clinically, hepatic fat in AN is usually macrovesicular, whereas microvesicular steatosis is more often associated with severe starvation and mitochondrial dysfunction.
Michiko Ishii +9 more
wiley +1 more source
ABSTRACT Although sphingolipids are key players in lipotoxicity and metabolic diseases, their response to bariatric surgery and their relation to metabolic improvement remain unclear. This pilot study investigated plasma sphingolipid remodeling after Roux‐en‐Y gastric bypass (RYGB) and its associations with clinical and biochemical markers of ...
Gabriela de Oliveira Lemos +3 more
wiley +1 more source
Lipid and food structure determine when and how macro‐ and micronutrients become bioaccessible. This review compares lipid bioaccessibility from engineered emulsions, breast milk, infant formula, and meat and meat mimics, which couples the effect of cooking temperature on lipid bioaccessibility in meat and eggs. ABSTRACT Food structure has emerged as a
Michael A. Rogers, Amanda J. Wright
wiley +1 more source
The goal of the Third Very Large Digital Library workshop is to discuss on-going implementations of Digital Libraries, hence to continue on providing researchers, practitioners and application developers with a forum fostering a constructive exchange among all key actors in the field of Very Large Digital Libraries.
Ioannidis Y., Manghi P., Pagano P.
openaire +1 more source
Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan +5 more
wiley +1 more source
ABSTRACT Objective We previously identified distinct muscle and liver insulin resistance (IR) metabotypes in middle‐aged and older adults. The PERSON study showed that a low‐fat, high‐protein, high‐fiber diet benefits the muscle IR group, while a high‐monounsaturated fatty acid diet benefits the liver IR group. We also developed the MetaboHealth score,
Jordi Morwani‐Mangnani +10 more
wiley +1 more source
ABSTRACT Objective This prespecified subpopulation analysis aimed to assess the efficacy and safety of once‐weekly tirzepatide versus placebo alongside lifestyle intervention in Japanese adults with obesity or overweight. Methods Data from 102 Japanese adults in the SURMOUNT‐1 trial with BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 and ≥ 1 weight‐related comorbidity ...
Yasushi Ishigaki +4 more
wiley +1 more source
Heart failure etiology and lipoprotein subfractions: Insight from the SMARTEX-HF study. [PDF]
Karlsen T +15 more
europepmc +1 more source
ABSTRACT Objectives To assess the prevalence and determinants of early pregnancy obesity (EPO) and its effects on the preterm cardiometabolic profile. Materials and Methods This study was conducted at the antenatal care unit of the Dschang district hospital.
Solange Dabou +5 more
wiley +1 more source

