Adiponectina iria determinar o predomínio de VLDL alteradas na síndrome metabólica [PDF]
El objetivo del trabajo fue evaluar si la reducción de adiponectina (ADP) en el síndrome metabólico (SMet), influencia las características aterogénicas de VLDL. Se estudiaron 45 pacientes con SMet y 15 controles sanos.
Berg, Gabriela Alicia+7 more
core
Cholesteryl ester transfer protein (CETP) inhibition leads to changes in lipoprotein metabolism. We studied the effect of the CETP inhibitor torcetrapib on VLDL apolipoprotein E (apoE) metabolism.
John S. Millar+14 more
doaj
Background/Aims: Hypertriglyceridaemia (HTG) and reduction and dysfunction of high density lipoprotein (HDL) are common lipid disturbances in chronic kidney disease (CKD). HTG in CKD is caused mainly by the decreased efficiency of lipoprotein lipase (LPL)
Agnieska Ćwiklińska+11 more
doaj +1 more source
Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation [PDF]
We tested the hypothesis that excessive portal venous supply of long-chain fatty acids to the liver contributes to the development of insulin resistance via activation of the hypothalamus-pituitary-adrenal axis (HPA axis) and sympathetic system.
Benthem, Lambertus,+7 more
core +1 more source
Genetic Determinants of the Familial Hypercholesterolaemia Phenotype
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley +1 more source
Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion.
AIM Present study aimed to elucidate the suppression of serum lipids by gamma- and delta-tocotrienol (γδT3). METHODS The lipid-lowering effects of γδT3 were investigated using HepG2 liver cell line, hypercholesterolemic mice and borderline-high ...
N. Zaiden+9 more
semanticscholar +1 more source
Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: An open label, non-randomized, controlled study [PDF]
Additional file 1: Table S1. Detailed baseline characteristics for participants in the continuous care intervention (CCI) and usual care (UC ...
Ballard, Kevin D+8 more
core +4 more sources
ABSTRACT Acne vulgaris is a common inflammatory condition that is often treated by dermatologists with isotretinoin. Isotretinoin has a number of effects on inflammatory pathways, with clear efficacy in managing acne vulgaris. There are also well‐documented side effects of isotretinoin, including hyperlipidemia; however, the overall cardiovascular risk
Timothy L. Cowan+3 more
wiley +1 more source
Hepatitis C virus and lipid metabolism: their implications in vaccine development and treatment
The hepatitis C virus (HCV) infects over 170 million people worldwide and is a leading cause of chronic hepatitis and severe forms of liver damage as cirrhosis and hepatocellular carcinoma.
Santiago Dueñas-Carrera
doaj
Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core +1 more source