Results 121 to 130 of about 66,180 (284)

Hepatic perfusate very low density lipoproteins obtained from fat-fed nonhuman primates stimulate cholesterol esterification in macrophages.

open access: yesJournal of Lipid Research, 1988
The livers of both baboons and rhesus monkeys fed a high fat, high cholesterol diet secreted very low density lipoproteins (VLDL) that were enriched in cholesteryl ester and apoe as compared to VLDL secreted by the livers of chow-fed animals. Stimulation
P A Soltys   +7 more
doaj  

Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity Reviews, EarlyView.
ABSTRACT Tirzepatide has positive effects on weight loss in individuals with overweight or obesity. Considering its broad side‐effect profile, its efficacy and safety in individuals without diabetes mellitus (DM) are yet to be fully understood. To address this, we conducted a comprehensive meta‐analysis of six randomized trials on individuals with ...
Sharath Kommu   +2 more
wiley   +1 more source

Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects

open access: yesJournal of Lipid Research, 2010
The effect of apolipoprotein (apo) E genotype on apoB-100 metabolism was examined in three normolipidemic apoE2/E2, five type III hyperlipidemic apoE2/E2, and five hyperlipidemic apoE3/E2 subjects using simultaneous administration of 131I-VLDL and 125I ...
Esther M.M. Ooi   +4 more
doaj  

Beta-VLDL [PDF]

open access: yes, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

open access: yesExperimental Physiology, EarlyView.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox   +8 more
wiley   +1 more source

High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDLs⃞

open access: yesJournal of Lipid Research, 2007
Withdrawing growth factors or serum from endothelial cells leads to the activation of effector caspases 3 and 7, resulting in apoptotic cell death. HDL protects against caspase induction through sphingosine-1-phosphate (S1P) receptors.
Mirta Mihovilovic   +4 more
doaj  

Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL [PDF]

open access: hybrid, 1998
Dominica Calvo   +4 more
openalex   +1 more source

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review

open access: yeseFood, Volume 6, Issue 4, August 2025.
Pomegranate parts (arils, peel, and flower) contain antioxidants, polyphenols, and flavonoids. These bioactives reduce inflammation, improve endothelial function, and modulate lipids. Regular intake lowers blood pressure, LDL, and atherosclerotic plaque while increasing HDL.
Esha Saeed   +11 more
wiley   +1 more source

Lipoprotein lipase- and hepatic triglyceride lipase-promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism

open access: yesJournal of Lipid Research, 2000
Apolipoprotein E (apoE) is the primary recognition signal on triglyceride-rich lipoproteins responsible for interacting with low density lipoprotein (LDL) receptors and LDL receptor-related protein (LRP).
Jheem D. Medh   +5 more
doaj  

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