Results 141 to 150 of about 53,616 (262)
A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques
Nature Medicine, 2021 Peng Zhang, Elisabeth Narayanan, Qingbo Liu, Y. Tsybovsky, K. Boswell, Shilei Ding, Zonghui Hu, D. Follmann, Yin Lin, H. Miao, H. Schmeisser, Denise Rogers, Samantha Falcone, Sayda M. Elbashir, Vladimir Presnyak, Kapil Bahl, Madhu Prabhakaran, Xuejun Chen, Edward K. Sarfo, D. Ambrozak, R. Gautam, MA Martin, Joanna Swerczek, Richard Herbert, D. Weiss, Johnathan Misamore, G. Ciaramella, Sunny Himansu, Guillaume B. E. Stewart-Jones, A. McDermott, R. Koup, J. Mascola, A. Finzi, A. Carfi, A. Fauci, P. Lusso +35 moresemanticscholar +1 more sourceLeadless Versus Transvenous Dual‐Chamber Pacemakers: Real‐World Evidence From AVEIR DR Coverage With Evidence Development Study
Journal of Cardiovascular Electrophysiology, EarlyView.ABSTRACT Background
AVEIR DR, an industry‐first dual‐chamber leadless pacemaker (LP), provides continuous atrioventricular synchrony through implant‐to‐implant (i2i) communication between atrial and ventricular LP devices. It is important to evaluate the early real‐world comparative safety of AVEIR DR LP.Monica Lo, Anish K. Amin, Marcin Kowalski, Anne Kroman, Dilip Mathew, Valay Parikh, Stanislav Weiner, Jennifer M. Joseph, Leonard Ganz, Mohammed Mortada, AVEIR DR Study Group/Consortium +10 morewiley +1 more sourcePhoton Assisted Tunneling of Zero Modes in a Majorana Wire
, 2019 Hybrid nanowires with proximity-induced superconductivity in the topological
regime host Majorana zero modes (MZMs) at their ends, and networks of such
structures can produce topologically protected qubits.Karzig, Torsten, Krogstrup, Peter, Marcus, Charles M., O'Farrell, Eoin C. T., Petersson, Karl D., Pikulin, Dmitry I., Razmadze, Davydas, Sabonis, Deividas, Suter, Judith, van Zanten, David M. T., Väyrynen, Jukka I. +10 morecore +1 more sourceFrench guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025
Journal of the European Academy of Dermatology and Venereology, EarlyView.New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.Marie Masson Regnault, Emilie Brenaut, Marie‐Emeline Marniquet, Carla Berthault, Lea Canoen, Clarisse Marcombes, Audrey Melin, Raphaël Ouakrat, Julie Charles, Stephane Mouret, Olivier Potie, Laetitia Penso, Laura Pina Vegas, Guillaume Larid, Marine Roux, Colombe Bougeard, Sandy Sylvain, Clara Labonne, Tania Randriamiarana, Da Hee Pitaud, Floriane Etheve, Jeremy Gottlieb, Laurie Gouillon, Marine Chastagner, Emilie Sbidian, Hélène Aubert, on behalf of the Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Société Française de Dermatologie), Hélène Aubert, Marie Masson Regnault, Emilie Brenaut, Emilie Sbidian, Laura Pina Vegas, Laetitia Penso, Jeremy Gottlieb, Marine Roux, Clara Labonne, Tania Randriamiarana, Floriane Etheve, Da Hee Pitaud, Marie‐Emeline Marniquet, Carla Berthault, Clarisse Marcombes, Audrey Melin, Colombe Bougeard, Julie Charles, Olivier Potie, Léa Canoen, Laurie Gouillon, Marine Chastagner, Sandy Sylvain, Guillaume Larid, Raphaël Ouakrat +51 morewiley +1 more sourceA single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex
Journal of Fish Biology, EarlyView.Abstract
A new single nucleotide polymorphism (SNP) panel for genetic stock identification in the Teno river Atlantic salmon, Salmo salar L., fishery was developed, with a view to improving on an existing microsatellite panel. Twenty‐two genetically differentiated reporting units were proposed based on population genetic analyses of 1212 individuals ...Helena Johansson, Jaakko Erkinaro, Morten Falkegård, Anders Foldvik, Panu Orell, Craig R. Primmer, Victoria L. Pritchard +6 morewiley +1 more sourceVirus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax
Vaccines, 2017 Vaccination is the most effective prophylactic tool against infectious diseases. Despite continued efforts to control malaria, the disease still generally represents a significant unmet medical need.Gustavo Cabral-Miranda, M. Heath, Mona O. Mohsen, A. Gomes, Paul Engeroff, A. Flaxman, Fabiana M. S. Leoratti, A. El-Turabi, A. Reyes‐Sandoval, M. Skinner, M. Kramer, M. Bachmann +11 moresemanticscholar +1 more sourceA Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies
Biotechnology and Bioengineering, Volume 123, Issue 3, Page 564-581, March 2026.ABSTRACT
The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn +4 morewiley +1 more sourceLipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity
Microbial Cell FactoriesBackground A cost-effective Escherichia coli expression system has gained popularity for producing virus-like particle (VLP) vaccines. However, the challenge lies in balancing the endotoxin residue and removal costs, as residual endotoxins can cause ...Xuegang Shen, Yong-Bo Yang, Yanfei Gao, Shujie Wang, Haiwei Wang, Mingxia Sun, Fandan Meng, Yan-Dong Tang, Yabin Tu, Qingke Kong, Tong-Qing An, Xue-Hui Cai +11 moredoaj +1 more sourceA nucleoside-modified mRNA vaccine forming rabies virus-like particle elicits strong cellular and humoral immune responses against rabies virus infection in mice
Emerging Microbes and InfectionsRabies is a lethal zoonotic disease that threatens human health. As the only viral surface protein, the rabies virus (RABV) glycoprotein (G) induces main neutralizing antibody (Nab) responses; however, Nab titre is closely correlated with the ...Jie Liu, Jie Sun, Xue Ding, Wenhao Liu, Yipeng Wang, Zihan Wang, Hanyu Peng, Yong Zhang, Weiheng Su, Chunlai Jiang +9 moredoaj +1 more source