Results 121 to 130 of about 23,750 (257)

Delivering Proteins and Enzymes to Solid Tumors Through the Development of Stimuli‐Responsive Nanocarriers

ChemNanoMat, Volume 12, Issue 6, June 2026.
Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo, Diana Benita‐Donadios, Sandra Jiménez‐Falcao, Alejandro Baeza   +3 more
wiley   +1 more source

Single vertical profiles showing correlations between VLP and prokaryotic subpopulations.

, 2016
(A) VLP 1 and VLP 2, (B) VLP 1 and LDNA at the sediment-water interface (r = 0.99, p < 0.0001); and (C) VLP 2 and HDNA 1, (D) LDNA and HDNA 1 at the air-water interface (r ≥ 0.97, p < 0.0001). Error bars represent 95% confidence intervals.
Kelly Newton (204031), Lisa M. Dann (603852), James G. Mitchell (165091), Rod Oliver (846506), James S. Paterson (756317)   +4 more
core   +1 more source

Aggressive squamous cell carcinomas arising from mucosal lichen planus: A report of three cases

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer, Dagmar Wilsmann‐Theis, Michael P. Schön, Jörg Wenzel, Julia Gallwas, Rotraut Mössner   +5 more
wiley   +1 more source

Media‐dependent performance of rabies virus‐like particle production under low oxygen tension in baculovirus‐infected Sf9 cells

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1273-1282, June 2026.
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello, Milena Miyu Teruya, Fernanda Angela Correia Barrence, Thaissa Consoni Bernardino, Jaci Leme, Luis Giovani de Oliveira Guardalini, Noemi Nosomi Taniwaki, Soraia Attie Calil Jorge, Eutimio Gustavo Fernández Núñez   +8 more
wiley   +1 more source

Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing

Microbiology Spectrum
Due to varying sequencing strategies, current gut virome findings show significant variability. Specifically, bulk- and virus-like particle (VLP)-enriched metagenomic sequencing (termed bulk and VLP, respectively) present unique advantages and ...
Yun Li, Chuqing Sun, Jiaying Zhu, Mingyan Geng, Min Li, Xing-Ming Zhao, Wei-Hua Chen   +6 more
doaj   +1 more source

Enterococcus faecalis Extracellular Vesicles Deliver the Bacterial GTPase Obg to Hijack mTOR Signalling in Hepatocellular Carcinoma

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
E. faecalis is enriched in HCC tissue and can promote liver tumourigenesis by activating mTOR signalling pathway. Obg derived from E. faecalis extracellular vesicles (EVs) is a GTPase physically interacts with mTOR, and acts as an interkingdom activator of mTOR. EF‐Obg expression level in HCC tissue correlates with poor prognosis in HCC patients.
Ning Ma, Xiaoshan Xie, Jiarui Wang, Zhikai Zheng, Huilin Jin, Xijie Chen, Xiaoling Huang, Haidan Luo, Yue Wei, Qihao Pan, Boyu Zhang, Jiaying Zheng, Peng Zhang, Fenghai Yu, Xue Liu, Zhi‐Min Zhang, Zhongguo Zhou, Xiangqi Meng, Mong‐Hong Lee   +18 more
wiley   +1 more source

Identification and purification of affinity selected VLP displayed peptides.

, 2014
(A) The sequence and structure of the AIP4 peptide. (B) 10 VLP clones were sequenced after three rounds of VLP affinity selection. Peptide inserts are shown and demonstrate little primary sequence homology to the native AIP4 peptide.
John P. O’Rourke (656238), Bryce Chackerian (66861), Seth M. Daly (282352), Kathleen D. Triplett (656239), Pamela R. Hall (282346), David Peabody (656240)   +5 more
core   +1 more source

114 VLPs and particle vaccines

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014
VLPs represent a powerful tool for vaccine development, representing the closest strategy to the native viruses for displaying and delivering conformational epitopes, with improved induction of antibodies and immune response in its whole. Moreover, the lack of genetic material makes VLPs the “safer counterpart” of live attenuated or killed viral ...
openaire   +2 more sources

The Effect of Limited Ankle Dorsiflexion During Emergency Stop—Jump Movements on Lower Limb Biomechanics

Journal of Foot and Ankle Research, Volume 19, Issue 2, June 2026.
ABSTRACT Objective The stop‐jump task is a key movement in sports such as basketball and volleyball, with landing biomechanics closely linked to injury risk. Restricted ankle dorsiflexion (DF) alters lower‐extremity mechanics and increases the risk of lower‐limb joint injuries; however, its effects on the full stop‐jump cycle remain unclear. This study
Yijing Zhou, Nan Yang, Qiaoqiao Wang, Yuan Wu, Haitao Shi, Si Zhang, Shuang Ren, Hongshi Huang   +7 more
wiley   +1 more source

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

Vox Sanguinis, EarlyView.
Pierre Tiberghien, Pierre Gallian, Virginie de La Taille, Caroline Bacquet, Syria Laperche   +4 more
wiley   +1 more source