Results 131 to 140 of about 23,750 (257)

Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede   +14 more
wiley   +1 more source

Thermostability of empty capsid (VLP) preparations.

open access: yes, 2017
Thermostability of empty capsid (VLP) preparations.
Sarah Knowlson (840444)   +3 more
core   +1 more source

Autonomous Navigation in Large‐Scale Underground Environments Based on a Purely Topological Understanding of Tunnel Networks

open access: yesJournal of Field Robotics, Volume 43, Issue 4, Page 2671-2692, June 2026.
ABSTRACT This work presents a non‐geometrical navigation approach based on a purely topological understanding of underground environments. By conceptualizing subterranean scenarios as a set of tunnels that intersect with each other, and taking a navigation approach based on topological instructions, we simplify the navigation problem to the sequential ...
Lorenzo Cano   +2 more
wiley   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik   +44 more
wiley   +1 more source

VLP-associated nucleic acids signal through MYD88 and TRIF.

open access: yes, 2013
RT-qPCR was used to analyze mRNA expression levels of the pro-inflammatory cytokines IL-1β and IL-6 20 hours after stimulation of WT, MyD88−/− or TRIF−/− DCs with 20 µg of VLP-1123, VLP-1632, VLP-1818, VLP-1965 or 1 µg of ODN 1826. Results represent mean
Marina De Filette (391004)   +10 more
core   +1 more source

Surgical Treatment of Distal Radius Fractures Using Minimally Invasive Plate Osteosynthesis or Open Reduction and Internal Fixation: A Five-Year Comparative Follow-Up Study

open access: yesApplied Sciences
Distal radius fractures (DRFs) constitute one of the most prevalent injuries in adults. This study compares the clinical and radiological outcomes of intra- and extra-articular DRFs treated with percutaneous Kirschner wires (PKW) or volar locking plates (
Giuseppe Rovere   +8 more
doaj   +1 more source

Rapid Quantification of Bacteriophages of Mycobacterium spp. and Related Genera in Aquatic Systems

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
Two qPCR assays (SYBR Green and TaqMan) targeting the major capsid protein gene of Myoviridae phages infecting Mycobacterium, Rhodococcus and Gordonia spp. were developed and optimised, enabling sensitive detection of these phages in freshwater systems.
Hanieh Shakeri Moghaddam, S. Jane Fowler
wiley   +1 more source

Zika virus-like particle (VLP) based vaccine.

open access: yes, 2017
The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders.
George R Martin   +13 more
core   +1 more source

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Changes in DOM composition influence prokaryotic species growth in the Mediterranean Sea, shaping their metabolic responses and organic matter processing. In our study, higher DOP consumption and alkaline phosphatase activity led to the accumulation of recalcitrant DOM, highlighting how microbial community shifts drive distinct pathways in carbon ...
Eva Ortega‐Retuerta   +9 more
wiley   +1 more source

Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy

open access: yesAllergy, Volume 81, Issue 6, Page 2156-2171, June 2026.
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi   +16 more
wiley   +1 more source

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