Results 111 to 120 of about 43,410 (236)

A nucleoside-modified mRNA vaccine forming rabies virus-like particle elicits strong cellular and humoral immune responses against rabies virus infection in mice

Emerging Microbes and Infections
Rabies is a lethal zoonotic disease that threatens human health. As the only viral surface protein, the rabies virus (RABV) glycoprotein (G) induces main neutralizing antibody (Nab) responses; however, Nab titre is closely correlated with the ...
Jie Liu, Jie Sun, Xue Ding, Wenhao Liu, Yipeng Wang, Zihan Wang, Hanyu Peng, Yong Zhang, Weiheng Su, Chunlai Jiang   +9 more
doaj   +1 more source

Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu, Shu Liu, Jurjen Heij, Laurens A. van de Mortel, Luka Liebrand, Matthan Caan, Wietske van der Zwaag, Dick J. Veltman, Lin Lu, Moji Aghajani, Guido van Wingen   +10 more
wiley   +1 more source

ACE2-Decorated Virus-Like Particles Effectively Block SARS-CoV-2 Infection

International Journal of Nanomedicine
Canan Bayraktar,1,* Alisan Kayabolen,1,* Arda Odabas,1 Aysegul Durgun,1 Ipek Kok,1 Kenan Sevinc,1 Aroon Supramaniam,2 Adi Idris,2,3 Tugba Bagci-Onder1 1Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul ...
Bayraktar C, Kayabolen A, Odabas A, Durgun A, Kok I, Sevinc K, Supramaniam A, Idris A, Bagci-Onder T   +8 more
doaj  

Enhancing NA immunogenicity through novel VLP designs.

Vaccine
Current influenza virus vaccines poorly display key neuraminidase (NA) epitopes and do not robustly induce NA-reactive antibodies; instead, they focus on the induction of hemagglutinin (HA)-reactive antibodies. Next-generation influenza vaccines should be optimized in order to activate NA-reactive B cells and to induce a broadly cross-reactive and ...
Guzman Ruiz, Leticia, Zollner, Alexander M., Hoxie, Irene, Küchler, Jan, Hausjell, Christina, Mesurado, Tomas, Krammer, Florian, Jungbauer, Alois, Pereira Aguilar, Patricia, Klausberger, Miriam, Grabherr, Reingard   +10 more
openaire   +3 more sources

Seamless Mobile Indoor Navigation With VLP-PDR

IEEE Sensors Journal
This study unveils a mobile app-based indoor positioning system (IPS) tailored for seamless museum navigation. Leveraging smartphone inertial measurement unit (IMU) sensors, it incorporates a pedestrian dead reckoning (PDR) algorithm and a visible light positioning (VLP) beacon-based angle of arrival (AoA) algorithm for precise user positioning ...
Aitor Alcázar-Fernández, Álvaro De-La-Llana-Calvo, José Luis Lázaro-Galilea, Antoni Pérez-Navarro, Rubén Gil-Vera, Alfredo Gardel-Vicente   +5 more
openaire   +3 more sources

Media‐dependent performance of rabies virus‐like particle production under low oxygen tension in baculovirus‐infected Sf9 cells

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1273-1282, June 2026.
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello, Milena Miyu Teruya, Fernanda Angela Correia Barrence, Thaissa Consoni Bernardino, Jaci Leme, Luis Giovani de Oliveira Guardalini, Noemi Nosomi Taniwaki, Soraia Attie Calil Jorge, Eutimio Gustavo Fernández Núñez   +8 more
wiley   +1 more source

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Changes in DOM composition influence prokaryotic species growth in the Mediterranean Sea, shaping their metabolic responses and organic matter processing. In our study, higher DOP consumption and alkaline phosphatase activity led to the accumulation of recalcitrant DOM, highlighting how microbial community shifts drive distinct pathways in carbon ...
Eva Ortega‐Retuerta, Nawal Bouchachi, Rebeca Campos, Olivier Crispi, Barbara Marie, Charles‐Hubert Paulin, Karine Escoubeyrou, Jonathan Colombet, Telesphore Sime‐Ngando, Anabel Von Jackowski   +9 more
wiley   +1 more source

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

European Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė, Milda Norkienė, Aurelija Žvirblienė, Asta Lučiūnaitė   +3 more
wiley   +1 more source

Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing

Microbiology Spectrum
Due to varying sequencing strategies, current gut virome findings show significant variability. Specifically, bulk- and virus-like particle (VLP)-enriched metagenomic sequencing (termed bulk and VLP, respectively) present unique advantages and ...
Yun Li, Chuqing Sun, Jiaying Zhu, Mingyan Geng, Min Li, Xing-Ming Zhao, Wei-Hua Chen   +6 more
doaj   +1 more source

Aggressive squamous cell carcinomas arising from mucosal lichen planus: A report of three cases

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer, Dagmar Wilsmann‐Theis, Michael P. Schön, Jörg Wenzel, Julia Gallwas, Rotraut Mössner   +5 more
wiley   +1 more source