Results 111 to 120 of about 23,750 (257)

Generation of chimeric HPV16 L1/L2-E7 VLP.

, 2015
A Sf-9 insect cells were infected with recombinant HPV16 L1/L2-E7 baculovirus and VLP purified by sucrose cushion and CsCl gradient centrifugation. Purified VLP, infected, and uninfected Sf-9 cell lysates were analyzed by SDS-PAGE and Coomassie staining.
Markus Wolschek (167359), Christoph Jindra (705992), Bettina Huber (705990), Thomas Muster (167361), Reinhard Kirnbauer (562348), Boris Ferko (225334), Sabine Brandt (123497), Saeed Shafti-Keramat (705994)   +7 more
core   +1 more source

Lipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity

Microbial Cell Factories
Background A cost-effective Escherichia coli expression system has gained popularity for producing virus-like particle (VLP) vaccines. However, the challenge lies in balancing the endotoxin residue and removal costs, as residual endotoxins can cause ...
Xuegang Shen, Yong-Bo Yang, Yanfei Gao, Shujie Wang, Haiwei Wang, Mingxia Sun, Fandan Meng, Yan-Dong Tang, Yabin Tu, Qingke Kong, Tong-Qing An, Xue-Hui Cai   +11 more
doaj   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Selective cytotoxicity of GCV to SPBtk-VLP–infected A549 cells.

, 2016
The viability of human cells—IMR32, HK2, and A549—was assessed by the CCK-8 method 72 hours after various treatments. The treatment combinations included PBS followed by PBS (PBS/PBS), control VLPs followed by PBS (VLP/PBS), pUMVC1-tk–packaged VLPs ...
Chun-Nun Chao (2847461), Mien-Chun Lin (2847452), Meilin Wang (119128), Pei-Lain Chen (2847455), Cheng-Huang Shen (2847467), Deching Chang (2847464), Chiung-Yao Fang (2847458)   +6 more
core   +1 more source

PRIMER REGISTRO DE ABUNDANCIA VIRAL EN BAHIA COLIUMO Y PLATAFORMA CONTINENTAL FRENTE A CHILE CENTRAL FIRST RECORD OF VIRAL ABUDANCE IN COLIUMO BAY AND THEand the continental shelf off central chile

Gayana, 2007
The abundance of virus like particles (VLP) was determined for the first time in the water column and sediment of Coliumo Bay and on a station on the continental shelf off central Chile.
Oscar E Chiang, Mathias Middelboe, Renato A Quiñones   +2 more
doaj  

A nucleoside-modified mRNA vaccine forming rabies virus-like particle elicits strong cellular and humoral immune responses against rabies virus infection in mice

Emerging Microbes and Infections
Rabies is a lethal zoonotic disease that threatens human health. As the only viral surface protein, the rabies virus (RABV) glycoprotein (G) induces main neutralizing antibody (Nab) responses; however, Nab titre is closely correlated with the ...
Jie Liu, Jie Sun, Xue Ding, Wenhao Liu, Yipeng Wang, Zihan Wang, Hanyu Peng, Yong Zhang, Weiheng Su, Chunlai Jiang   +9 more
doaj   +1 more source

Formation of Shallow Cumulus Patterns Using a Simple Warm Cloud Precipitation Model

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 12, 28 June 2026.
Abstract A simple model based on predator‐prey‐like dynamics using a system of four nonlinear ordinary differential equations is used to simulate the life cycle of shallow cumulus. By coupling this model across a two‐dimensional array and varying the cloud environment, we can simulate three common patterns of self‐aggregation seen in the maritime ...
Michelle K. Kanipe, Peter J. van Leeuwen, Graham Feingold   +2 more
wiley   +1 more source

ACE2-Decorated Virus-Like Particles Effectively Block SARS-CoV-2 Infection

International Journal of Nanomedicine
Canan Bayraktar,1,* Alisan Kayabolen,1,* Arda Odabas,1 Aysegul Durgun,1 Ipek Kok,1 Kenan Sevinc,1 Aroon Supramaniam,2 Adi Idris,2,3 Tugba Bagci-Onder1 1Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul ...
Bayraktar C, Kayabolen A, Odabas A, Durgun A, Kok I, Sevinc K, Supramaniam A, Idris A, Bagci-Onder T   +8 more
doaj  

Encapsulin‐Protected Immunotherapeutic Complexes: Bacteria‐Derived Nanoparticles for mRNA Delivery to Eukaryotic Cells

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
Here, we introduce a biological, self‐assembling supramolecular nanoparticle designed to encapsulate eukaryotic‐expressible mRNA within an encapsulin shell via an encapsulin‐RNA adaptor peptide (ERAP). This process occurs in bacteria, and the resulting complex can deliver its mRNA into eukaryotic cells, where it is expressed.
Carlos Francisco Coffeen, Maribel Cayetano‐Cruz, Damaris Ilhuicatzi‐Alvarado, Carmen Méndez, Leticia Moreno‐Fierros, Ismael Bustos‐Jaimes   +5 more
wiley   +1 more source

Nature's Nanotech Warriors: The Role of Metalloproteins and Protein Cages for Environmental Remediation

Advanced Sustainable Systems, Volume 10, Issue 6, June 2026.
Cartoon representation of five major classes of metalloproteins and their brief mechanisms of bioremediation. The five classes include metallothioneins, metal‐precipitating enzymes, P.‐type ATPases, protein cages, and synthetic metalloproteins (de novo‐designed proteins/peptides for selective adsorption). These natural and engineered protein structures
Sian D'Silva, Celin Acharya, Soumyananda Chakraborti   +2 more
wiley   +1 more source