Results 111 to 120 of about 25,779 (213)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing

Microbiology Spectrum
Due to varying sequencing strategies, current gut virome findings show significant variability. Specifically, bulk- and virus-like particle (VLP)-enriched metagenomic sequencing (termed bulk and VLP, respectively) present unique advantages and ...
Yun Li, Chuqing Sun, Jiaying Zhu, Mingyan Geng, Min Li, Xing-Ming Zhao, Wei-Hua Chen   +6 more
doaj   +1 more source

Attention Based Optimization for 3D Shape Registration

Computer Graphics Forum, EarlyView.
Abstract Transformers are sequence‐to‐sequence architectures originally designed to handle structurally rigid and order‐sensitive data, such as text and images. At their core, they exploit the attention mechanism, which is permutation‐equivariant and relies on computing token‐to‐token relationships.
A. Riva, L. Olearo, S. Melzi
wiley   +1 more source

Single vertical profiles showing correlations between VLP and prokaryotic subpopulations.

, 2016
(A) VLP 1 and VLP 2, (B) VLP 1 and LDNA at the sediment-water interface (r = 0.99, p < 0.0001); and (C) VLP 2 and HDNA 1, (D) LDNA and HDNA 1 at the air-water interface (r ≥ 0.97, p < 0.0001). Error bars represent 95% confidence intervals.
Kelly Newton (204031), Lisa M. Dann (603852), James G. Mitchell (165091), Rod Oliver (846506), James S. Paterson (756317)   +4 more
core   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Surgical Treatment of Distal Radius Fractures Using Minimally Invasive Plate Osteosynthesis or Open Reduction and Internal Fixation: A Five-Year Comparative Follow-Up Study

Applied Sciences
Distal radius fractures (DRFs) constitute one of the most prevalent injuries in adults. This study compares the clinical and radiological outcomes of intra- and extra-articular DRFs treated with percutaneous Kirschner wires (PKW) or volar locking plates (
Giuseppe Rovere, Pierfrancesco Pirri, Gianmarco Murgante, Vincenzo De Luna, Aurelio Testa, Giovanna Fidone, Francesco Liuzza, Pasquale Farsetti, Fernando De Maio   +8 more
doaj   +1 more source

A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex

Journal of Fish Biology, EarlyView.
Abstract A new single nucleotide polymorphism (SNP) panel for genetic stock identification in the Teno river Atlantic salmon, Salmo salar L., fishery was developed, with a view to improving on an existing microsatellite panel. Twenty‐two genetically differentiated reporting units were proposed based on population genetic analyses of 1212 individuals ...
Helena Johansson, Jaakko Erkinaro, Morten Falkegård, Anders Foldvik, Panu Orell, Craig R. Primmer, Victoria L. Pritchard   +6 more
wiley   +1 more source

Ventricular Pacing Inhibition After Dual‐Chamber Leadless Pacing Associated With a Retained Right Ventricular Lead

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT An 88‐year‐old pacemaker‐dependent man with a retained low‐impedance, noise‐producing right ventricular lead underwent implantation of a dual‐chamber leadless pacemaker. On postoperative day 1, he developed recurrent syncope with pauses up to 13 s.
Yuya Nakamura, Takamasa Ishikawa, Shuhei Arai, Kosuke Yoshikawa, Taku Asano, Toshiro Shinke   +5 more
wiley   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Optimisation de la production de cGAMP-VLP et développement de cGAMP-VLP ciblées

, 2020
L'ADN double brin chez les mammifères est présent exclusivement dans le noyau et les mitochondries. Sa présence dans le cytosol est un marqueur d'infection virale ou de stress cellulaire.
Bochnakian, Aurore
core