Results 91 to 100 of about 25,779 (213)

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

open access: yesSmall, EarlyView.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey   +2 more
wiley   +1 more source

Self‐Assembly of Hierarchically Structured Materials From Liquid Crystalline Mesophases of Tobacco Mosaic Virus‐Like Particles

open access: yesSmall, EarlyView.
Recombinantly produced Tobacco Mosaic Virus coat protein (TMVcp) helical rods were demonstrated to reproducibly self‐assemble into hierarchically structured macroscopic filaments, driven by a lyotropic liquid crystal (LC) intermediate phase. The results indicate anisotropic molecular alignment of the fluid phase, retention of the native secondary ...
Guido M. Merino   +2 more
wiley   +1 more source

Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures-A 3-year cost-utility analysis.

open access: yesPLoS ONE, 2020
AimTo investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective.MethodsDuring 2009-2013, patients aged 50-74 years with an unstable ...
Jenny Saving   +4 more
doaj   +1 more source

Fusion Energy and Tritium Fuel Cycle: Hydrogen Isotope Separation Technologies and Sorbent Materials

open access: yesSmall Methods, EarlyView.
This review surveys sorbent‐based materials for hydrogen isotope separation, a key challenge in fusion fuel processing. Different types of adsorbents are compared in terms of selectivity, kinetics, and operational practicality. Limitations of cryogenic operation and tritium compatibility are highlighted, providing guidance toward efficient, low tritium
Pankaj Sharma   +2 more
wiley   +1 more source

Enhanced mannosylated VLP uptake is due to mannose receptor association.

open access: yes, 2014
Murine splenocytes were left untreated (white bars) or treated with 3 mg mL−1 mannann (grey bars) before a 1 hour incubation with DyLight labeled; VLP, monomannose-VLP (M-VLP) or dimannose-VLP (D-VLP) then analyzed by flow cytometry to determine the mean
Margaret A. Baird (615879)   +4 more
core   +1 more source

Vision language models for bridge inspections: A review of applications in image‐based damage documentation

open access: yesStructural Concrete, EarlyView.
Abstract Automating bridge inspections requires more than detecting individual damage instances. It demands systems capable of describing, contextualizing, and interpreting damage in an inspection‐relevant manner. Conventional computer vision approaches, such as object detection and segmentation, primarily address visual recognition tasks and are ...
Rona Firdes Çelik   +2 more
wiley   +1 more source

A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

open access: yesEmerging Microbes and Infections, 2018
Hand, foot, and mouth disease (HFMD) is an infectious disease that mainly affects infants and children, causing considerable morbidity and mortality worldwide.
Wei Zhang   +9 more
doaj   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão   +12 more
wiley   +1 more source

Selective cytotoxicity of GCV to SPBtk-VLP–infected A549 cells.

open access: yes, 2016
The viability of human cells—IMR32, HK2, and A549—was assessed by the CCK-8 method 72 hours after various treatments. The treatment combinations included PBS followed by PBS (PBS/PBS), control VLPs followed by PBS (VLP/PBS), pUMVC1-tk–packaged VLPs ...
Chun-Nun Chao (2847461)   +6 more
core   +1 more source

PRIMER REGISTRO DE ABUNDANCIA VIRAL EN BAHIA COLIUMO Y PLATAFORMA CONTINENTAL FRENTE A CHILE CENTRAL FIRST RECORD OF VIRAL ABUDANCE IN COLIUMO BAY AND THEand the continental shelf off central chile

open access: yesGayana, 2007
The abundance of virus like particles (VLP) was determined for the first time in the water column and sediment of Coliumo Bay and on a station on the continental shelf off central Chile.
Oscar E Chiang   +2 more
doaj  

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