Results 71 to 80 of about 18,155 (206)

Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures-A 3-year cost-utility analysis.

PLoS ONE, 2020
AimTo investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective.MethodsDuring 2009-2013, patients aged 50-74 years with an unstable ...
Jenny Saving, Emelie Heintz, Hans Pettersson, Anders Enocson, Cecilia Mellstrand Navarro   +4 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

Emerging Microbes and Infections, 2018
Hand, foot, and mouth disease (HFMD) is an infectious disease that mainly affects infants and children, causing considerable morbidity and mortality worldwide.
Wei Zhang, Wenlong Dai, Chao Zhang, Yu Zhou, Pei Xiong, Shuxia Wang, Xiaohua Ye, Qingwei Liu, Dongming Zhou, Zhong Huang   +9 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex

Journal of Fish Biology, EarlyView.
Abstract A new single nucleotide polymorphism (SNP) panel for genetic stock identification in the Teno river Atlantic salmon, Salmo salar L., fishery was developed, with a view to improving on an existing microsatellite panel. Twenty‐two genetically differentiated reporting units were proposed based on population genetic analyses of 1212 individuals ...
Helena Johansson, Jaakko Erkinaro, Morten Falkegård, Anders Foldvik, Panu Orell, Craig R. Primmer, Victoria L. Pritchard   +6 more
wiley   +1 more source

Lipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity

Microbial Cell Factories
Background A cost-effective Escherichia coli expression system has gained popularity for producing virus-like particle (VLP) vaccines. However, the challenge lies in balancing the endotoxin residue and removal costs, as residual endotoxins can cause ...
Xuegang Shen, Yong-Bo Yang, Yanfei Gao, Shujie Wang, Haiwei Wang, Mingxia Sun, Fandan Meng, Yan-Dong Tang, Yabin Tu, Qingke Kong, Tong-Qing An, Xue-Hui Cai   +11 more
doaj   +1 more source

Ventricular Pacing Inhibition After Dual‐Chamber Leadless Pacing Associated With a Retained Right Ventricular Lead

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT An 88‐year‐old pacemaker‐dependent man with a retained low‐impedance, noise‐producing right ventricular lead underwent implantation of a dual‐chamber leadless pacemaker. On postoperative day 1, he developed recurrent syncope with pauses up to 13 s.
Yuya Nakamura, Takamasa Ishikawa, Shuhei Arai, Kosuke Yoshikawa, Taku Asano, Toshiro Shinke   +5 more
wiley   +1 more source

PRIMER REGISTRO DE ABUNDANCIA VIRAL EN BAHIA COLIUMO Y PLATAFORMA CONTINENTAL FRENTE A CHILE CENTRAL FIRST RECORD OF VIRAL ABUDANCE IN COLIUMO BAY AND THEand the continental shelf off central chile

Gayana, 2007
The abundance of virus like particles (VLP) was determined for the first time in the water column and sediment of Coliumo Bay and on a station on the continental shelf off central Chile.
Oscar E Chiang, Mathias Middelboe, Renato A Quiñones   +2 more
doaj  

Evaluation of cellular immune response and biosafety of SV40 virus-like particle in tumor immunotherapy

Journal of Materials Science: Materials in Medicine
Virus-like particle (VLP) holds great promise for applications in vaccines and tumor immunotherapy. However, their clinical translation has been limited by a lack of comprehensive in vivo studies on immune responses and antigenic toxicity. In this study,
Ting He, Ruoxuan Hei, Chong Liu, Huiping Wang, Zhaowei Gao, Ke Dong, Juan Zhang   +6 more
doaj   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source