Results 81 to 90 of about 26,425 (258)
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine. [PDF]
PLoS ONE, 2012 Murabutide (MB) is a synthetic immunomodulator recognized by the nucleotide-binding oligomerization domain-containing protein 2 (NOD2) receptor on mammalian cells. MB has previously been approved for testing in multiple human clinical trials to determine
Erin M Jackson +1 more
doaj +1 more source
Immunogenicity of VLP-VP2 in mice (determination of antibody titers of VLP-VP2 in mice).
, 2014 Immunogenicity of VLP-VP2 in mice (determination of antibody titers of VLP-VP2 in mice).
Yu-wei Gao (510434) +13 more
core +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía +3 more
wiley +1 more source
Uptake of mannosylated VLP in human APCs is dependent on mannose receptor association.
, 2014 Human monocyte-derived DCs and macrophages were left untreated (white bars) or treated with 3 mg mL−1 mannan (grey bars) before a 1 hour incubation with DyLight labeled; VLP, monomannose-VLP (M-VLP) or dimannose-VLP (D-VLP) then analyzed by flow ...
Margaret A. Baird (615879) +4 more
core +1 more source
, 2023 Virus-like particle (VLP)-based vaccines are required to be associated with a suitable adjuvant to potentiate their immune responses. Herein, we report a novel, biodegradable, and biocompatible polyphosphoester-based amphiphilic cationic polymer, poly ...
Chen, Rongjun +6 more
core +1 more source
Deep Underground Science and Engineering, EarlyView.Fault slip can occur ahead of the injection pressure front due to poroelastic stress. Our model captures the interaction of pressure, stress, and friction, providing new insights into injection‐induced seismicity and post‐injection fault slip. Shut‐in operations can either mitigate or accelerate seismic events depending on fault conditions and ...
Qifeng Xie, Lei Wang, Qi Li
wiley +1 more source
Thermostability of empty capsid (VLP) preparations.
, 2017 Thermostability of empty capsid (VLP) preparations.
Sarah Knowlson (840444) +3 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta +5 more
wiley +1 more source
Optimal Transmission Performance of Quadrature Wireless Resonators at 3 T
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To demonstrate a method for optimizing the efficiency of wireless resonators using tailored excitation from a dual‐transmit birdcage coil (BC), and to present the design and experimental investigation of a quadrature resonator for 3 T breast MRI application.
Leila Sharipova +7 more
wiley +1 more source