Results 81 to 90 of about 43,410 (236)
Temporal Dynamics of Parkinson's Disease Tremor: Clinical and Neuroimaging Insights
Movement Disorders, EarlyView.Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder clinically defined by three cardinal motor symptoms: bradykinesia, rigidity, and tremor. Although the natural history of bradykinesia and rigidity is well described, the evolution of tremor as the disease progresses remains controversial. Objectives The goal was to
Melanie Suette +15 more
wiley +1 more source
Hubble Diagram of Gamma-Rays Bursts calibrated with Gurzadyan-Xue Cosmology
, 2008 Gamma-ray bursts (GRBs) being the most luminous among known cosmic objects carry an essential potential for cosmological studies if properly used as standard candles.
Cuesta, H. J. Mosquera +5 more
core +1 more source
Journal of Field Robotics, EarlyView.ABSTRACT This work presents a non‐geometrical navigation approach based on a purely topological understanding of underground environments. By conceptualizing subterranean scenarios as a set of tunnels that intersect with each other, and taking a navigation approach based on topological instructions, we simplify the navigation problem to the sequential ...
Lorenzo Cano +2 more
wiley +1 more source
Mesothelin virus-like particle immunization controls pancreatic cancer growth through CD8+ T cell induction and reduction in the frequency of CD4+ foxp3+ ICOS- regulatory T cells. [PDF]
PLoS ONE, 2013 Our previous study has shown that mesothelin (MSLN) is a potential immunotherapeutic target for pancreatic cancer. Here, we further studied the immunogenicity of chimeric murine MSLN-virus-like particles (mMSLN-VLPs), their ability to break tolerance to ...
Sheng Zhang +5 more
doaj +1 more source
Ground‐based robotic remote sensing for standardized biodiversity monitoring in coastal habitats
Remote Sensing in Ecology and Conservation, EarlyView.Illustrated workflow of the proposed citizen‐to‐robot monitoring pipeline: (i) expert‐validated citizen observations are translated into AI models, (ii) deployed on a ground‐based robotic platform for proximal sensing of coastal dune habitats, (iii) enabling standardized detection of ecological targets (e.g., Pancratium maritimum & Brithys crini), and (
Giovanni Di Lorenzo +5 more
wiley +1 more source
Earth, Planets and Space, 2018 The April 27, 2016 eruption sequence at White Island was comprised of 6 discrete eruptive events that occurred over a 35-min period. Seismicity included three episodes of VLP activity: the first occurring ~ 2 h and a second occurring 10 min prior to the ...
Arthur Jolly +3 more
doaj +1 more source
Peptide‐Ligand Cooperative Interplay Drives Gold Nanoparticle Encapsulation by Protein Cages
Small, EarlyView.Gold nanoparticle encapsulation within protein cages is governed by salt‐dependent binding energetics and cooperative peptide–ligand interactions. Ligands enhance electrostatic attraction while peptides extend recruitment and prevent kinetic trapping, enabling robust cargo loading. This molecular‐level insight links experiments and simulations, guiding
Wenhui Li +5 more
wiley +1 more source
PLoS ONE, 2019 BACKGROUND:Malaria caused by Plasmodium falciparum is one of the major threats to human health globally. Despite huge efforts in malaria control and eradication, highly effective vaccines are urgently needed, including vaccines that can block malaria ...
David Wetzel +15 more
doaj +1 more source
Production of Norovirus VLPs to size homogeneity
Virus Research, 2015 Expression of full-length major capsid protein of Noroviruses (NoVs) in sf9 cells using recombinant baculovirus expression system leads to the formation of virus-like particles (VLPs) with two sizes. In our pursuit of VLPs with uniform sizes, we find that N terminal truncated capsid protein formed primary VLPs with an average size of 21 nm.
Yuqi, Huo +4 more
openaire +2 more sources
Environmental Toxicology, EarlyView.ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source