Results 101 to 110 of about 26,425 (258)

Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures-A 3-year cost-utility analysis.

PLoS ONE, 2020
AimTo investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective.MethodsDuring 2009-2013, patients aged 50-74 years with an unstable ...
Jenny Saving, Emelie Heintz, Hans Pettersson, Anders Enocson, Cecilia Mellstrand Navarro   +4 more
doaj   +1 more source

Generation of chimeric HPV16 L1/L2-E7 VLP.

, 2015
A Sf-9 insect cells were infected with recombinant HPV16 L1/L2-E7 baculovirus and VLP purified by sucrose cushion and CsCl gradient centrifugation. Purified VLP, infected, and uninfected Sf-9 cell lysates were analyzed by SDS-PAGE and Coomassie staining.
Markus Wolschek (167359), Christoph Jindra (705992), Bettina Huber (705990), Thomas Muster (167361), Reinhard Kirnbauer (562348), Boris Ferko (225334), Sabine Brandt (123497), Saeed Shafti-Keramat (705994)   +7 more
core   +1 more source

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

Small, EarlyView.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey, Alexander J. Bryer, Juan R. Perilla   +2 more
wiley   +1 more source

Immune components required for post-exposure VLP protection.

, 2015
(A) Various knockout mice were infected with EBOV and treated with VLPs 24 hours later. n = 10 (n = 20 for perforin and no VLP), 2 separate experiments. Nineteen of out 20 VLP treated control WT mice survived infection.
Sina Bavari (154739), Carl I. Shaia (704916), Natarajan Ayithan (696321), Scott M. Anthony (531045), Kelly S. Stuthman (696322), Keiko Ozato (25065), Steven B. Bradfute (262649), Mike Bray (18300), Prafullakumar Tailor (704915)   +8 more
core   +1 more source

Self‐Assembly of Hierarchically Structured Materials From Liquid Crystalline Mesophases of Tobacco Mosaic Virus‐Like Particles

Small, EarlyView.
Recombinantly produced Tobacco Mosaic Virus coat protein (TMVcp) helical rods were demonstrated to reproducibly self‐assemble into hierarchically structured macroscopic filaments, driven by a lyotropic liquid crystal (LC) intermediate phase. The results indicate anisotropic molecular alignment of the fluid phase, retention of the native secondary ...
Guido M. Merino, Matthew J. Harrington, Amy Szuchmacher Blum   +2 more
wiley   +1 more source

A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

Emerging Microbes and Infections, 2018
Hand, foot, and mouth disease (HFMD) is an infectious disease that mainly affects infants and children, causing considerable morbidity and mortality worldwide.
Wei Zhang, Wenlong Dai, Chao Zhang, Yu Zhou, Pei Xiong, Shuxia Wang, Xiaohua Ye, Qingwei Liu, Dongming Zhou, Zhong Huang   +9 more
doaj   +1 more source

Bone marrow dendritic cells internalize live RF-81 bovine rotavirus and rotavirus-like particles (RF 2/6-GFP-VLP and RF 8*2/6/7-VLP) but are only activated by live bovine rotavirus

, 2007
International audienceDendritic cells (DC) represent the link between innate and adaptive immunity. They are classified as antigen-presenting cells (APC) and can initiate and modulate the immune response.
Hinkula, J., Svensson, L., Istrate, C., Poncet, D, Istrate, C, Poncet, Didier, Hidmark, Å, Magnusson, K.E., Mcinerney, G.M., McInnerney, GM, Charpilienne, Annie, Douagi, I., Larsson, M., Svensson, Lennart,, Douagi, I,, Magnusson, K-E, Larsson, M, Magnusson, Karl-Eric,, Johansen, K., Johansen, K, Douagi, I, Hinkula, Jorma,, Charpilienne, A, Larsson, Marie,, Hidmark, A., Svensson, L,, McInerney, GM   +26 more
core   +1 more source

Hepatitis B core (HBc) virus like particle (VLP) as a platform for innovation of chimeric adjuvant-free VLP vaccines targeting oncoviruses [PDF]

, 2021
Immunotherapy is an advanced technology for treatment of oncoviruses leading cancers. However, lack of effective and safe vaccines against the oncoviruses has limited the development.
Zhang, Bingyang
core  

Development of seasonal influenza virus-like particle (VLP) vaccines using insect cell-based baculovirus expressing system

, 2023
[[abstract]]Intro: Influenza viruses are highly infectious and cause widespread respiratory diseases. Moreover, it could pose a noteworthy epidemic and pandemic threat to public health.
Badruzzaman, ATM;Cheng, YC;Sung, WC;Huang, CY;Lee, MS
core   +1 more source

Vision language models for bridge inspections: A review of applications in image‐based damage documentation

Structural Concrete, EarlyView.
Abstract Automating bridge inspections requires more than detecting individual damage instances. It demands systems capable of describing, contextualizing, and interpreting damage in an inspection‐relevant manner. Conventional computer vision approaches, such as object detection and segmentation, primarily address visual recognition tasks and are ...
Rona Firdes Çelik, Ulas Bagci, Sylvia Kessler   +2 more
wiley   +1 more source