Results 51 to 60 of about 25,779 (213)
Modular vaccine platform based on the norovirus-like particle
Journal of Nanobiotechnology, 2021 Background Virus-like particle (VLP) vaccines have recently emerged as a safe and effective alternative to conventional vaccine technologies. The strong immunogenic effects of VLPs can be harnessed for making vaccines against any pathogen by decorating ...
Vili Lampinen +6 more
doaj +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
6. “I Hope He’s Appreciating the Presence” | The 2023 UCF VLP Institute Podcast Series
, 2023 In the sixth episode of “The 2023 UCF VLP Institute Podcast Series,” we’ve reached the climax. At this point in the series, you have heard seven teachers, ranging from 2nd grade to 11th grade, profoundly reflect on their experience at the Institute—from ...
Garcia, Sebastian
core
Immunization with Virus-Like Particle Vaccine Protects Rabbits against Hepatitis E-3 Virus Infection
Viruses, 2022 Here, rabbits were immunized with a virus-like particle (VLP) vaccine prepared by expressing 239 amino acids of the swine hepatitis E virus (HEV)-3 capsid protein using a baculovirus system.
Hyeon-Jeong Go +13 more
doaj +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2017 Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (
Hye Suk Hwang +10 more
doaj +1 more source
BMC Research Notes, 2023 Objective Studies have shown that Flavivirus infection remodels the host cell to favour viral replication. In particular, the host cell lipid profile is altered, and it has been proposed that this process alters membrane fluidity to allow wrapping of the
Suwipa Ramphan +8 more
doaj +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Lignocellulosic residues are non‐cost, non‐edible, renewable feedstocks that can be used in polyhydroxybutyrate (PHB) production. PHB is a bioplastic synthetized by microorganisms, formed intracellularly under stressful growth conditions; however, its production costs are high, representing the major drawback for fossil‐based plastics ...
Clara Matte Borges Machado +8 more
wiley +1 more source
Characterization of influenza M2 VLP.
, 2013 (A) Western blotting of M2 VLP and recombinant M2e protein. M2 VLP (Lane 1; 0.5ug total protein) and recombinant M2e protein (Lane 2, 3, 4; 15, 30 60 ng respectively) were loaded and detected by western blotting using mouse anti-M2e monoclonal antibody ...
Kyoung-Mi Park (329009) +9 more
core +1 more source