Results 51 to 60 of about 26,425 (258)
MOESM1 of A thermostable, chromatographically purified Ebola nano-VLP vaccine
, 2016 Additional file 1: Figure S1. Quantitation of GP in VLP by ELISA. Figure S2. Nanopore measurements of VLP samples. Figure S3. SDS-PAGE comparison of Nano-VLP preparation with sucrose-gradient purified VLP. Figure S4. Electron micrographs of Nano-VLP with
Sina Bavari (154739) +5 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
The choice of resin-bound ligand affects the structure and immunogenicity of column-purified human papillomavirus type 16 virus-like particles. [PDF]
PLoS ONE, 2012 Cell growth conditions and purification methods are important in determining biopharmaceutical activity. However, in studies aimed at manufacturing virus-like particles (VLPs) for the purpose of creating a prophylactic vaccine and antigen for human ...
Hyoung Jin Kim +3 more
doaj +1 more source
Enhanced mannosylated VLP uptake is due to mannose receptor association.
, 2014 Murine splenocytes were left untreated (white bars) or treated with 3 mg mL−1 mannann (grey bars) before a 1 hour incubation with DyLight labeled; VLP, monomannose-VLP (M-VLP) or dimannose-VLP (D-VLP) then analyzed by flow cytometry to determine the mean
Margaret A. Baird (615879) +4 more
core +1 more source
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Frontiers in Immunology, 2017 Influenza virus M2 extracellular domain (M2e) has been a target for developing cross-protective vaccines. However, the efficacy and immune correlates of M2e vaccination are poorly understood in the different host genetic backgrounds in comparison with ...
Yu-Jin Kim +9 more
doaj +1 more source
Modular vaccine platform based on the norovirus-like particle
Journal of Nanobiotechnology, 2021 Background Virus-like particle (VLP) vaccines have recently emerged as a safe and effective alternative to conventional vaccine technologies. The strong immunogenic effects of VLPs can be harnessed for making vaccines against any pathogen by decorating ...
Vili Lampinen +6 more
doaj +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Immunization with Virus-Like Particle Vaccine Protects Rabbits against Hepatitis E-3 Virus Infection
Viruses, 2022 Here, rabbits were immunized with a virus-like particle (VLP) vaccine prepared by expressing 239 amino acids of the swine hepatitis E virus (HEV)-3 capsid protein using a baculovirus system.
Hyeon-Jeong Go +13 more
doaj +1 more source
VLP-associated nucleic acids signal through MYD88 and TRIF.
, 2013 RT-qPCR was used to analyze mRNA expression levels of the pro-inflammatory cytokines IL-1β and IL-6 20 hours after stimulation of WT, MyD88−/− or TRIF−/− DCs with 20 µg of VLP-1123, VLP-1632, VLP-1818, VLP-1965 or 1 µg of ODN 1826. Results represent mean
Marina De Filette (391004) +10 more
core +1 more source