Results 51 to 60 of about 23,750 (257)

Generation and immunogenicity assessment of ELPylated virus-like particles of porcine circovirus type 2

open access: yesVirology Journal, 2020
Background Porcine circovirus type 2 (PCV2) is an economically important pathogen affecting swine industry worldwide. The production of current PCV2 vaccines is time-consuming and expensive.
Yangyang Li   +7 more
doaj   +1 more source

Expression of dengue virus and Zika virus NS2B-NS3pro constructs alter cellular fatty acids, but co-expression with a Zika virus virus-like particle is detrimental to virus-like particle expression

open access: yesBMC Research Notes, 2023
Objective Studies have shown that Flavivirus infection remodels the host cell to favour viral replication. In particular, the host cell lipid profile is altered, and it has been proposed that this process alters membrane fluidity to allow wrapping of the
Suwipa Ramphan   +8 more
doaj   +1 more source

Production of Norovirus VLPs to size homogeneity

open access: yesVirus Research, 2015
Expression of full-length major capsid protein of Noroviruses (NoVs) in sf9 cells using recombinant baculovirus expression system leads to the formation of virus-like particles (VLPs) with two sizes. In our pursuit of VLPs with uniform sizes, we find that N terminal truncated capsid protein formed primary VLPs with an average size of 21 nm.
Yuqi, Huo   +4 more
openaire   +2 more sources

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh   +7 more
wiley   +1 more source

VLP surface modification.

open access: yes, 2014
(A) TEM micrograph of monomannose-VLP (negatively stained with PTA). Scale bar = 200 nm. (B) RHDV VP60 model generated by I-TASSER, with the VLP P domain (top) and the shell domain (bottom, shaded).
Margaret A. Baird (615879)   +4 more
core   +1 more source

Modular vaccine platform based on the norovirus-like particle

open access: yesJournal of Nanobiotechnology, 2021
Background Virus-like particle (VLP) vaccines have recently emerged as a safe and effective alternative to conventional vaccine technologies. The strong immunogenic effects of VLPs can be harnessed for making vaccines against any pathogen by decorating ...
Vili Lampinen   +6 more
doaj   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

6. “I Hope He’s Appreciating the Presence” | The 2023 UCF VLP Institute Podcast Series

open access: yes, 2023
In the sixth episode of “The 2023 UCF VLP Institute Podcast Series,” we’ve reached the climax. At this point in the series, you have heard seven teachers, ranging from 2nd grade to 11th grade, profoundly reflect on their experience at the Institute—from ...
Garcia, Sebastian
core  

SCOPE KM1605 VLP abundance

open access: yes, 2020
SCOPE KM1605 VLP ...
Lindell lab
core   +1 more source

Virus-like particle vaccines: immunology and formulation for clinical translation

open access: yesExpert Review of Vaccines, 2018
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation from laboratory models, to routine clinical administration. While some VLP vaccines thrive and are readily adopted into the vaccination schedule, others are
Braeden Donaldson   +4 more
doaj   +1 more source

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