Results 41 to 50 of about 26,425 (258)
Virus Research, 2023 Background: Human metapneumovirus (HMPV) causes respiratory tract infections among infant, elderly, and immunocompromised patients, with significant mortality. Currently no licensed vaccines or therapeutic agents of HMPV exist.
Fenlian Ma +6 more
doaj +1 more source
Packaging of actin into Ebola virus VLPs [PDF]
Virology Journal, 2005 Abstract The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses. In this report, we sought to determine whether actin is incorporated into Ebola VLPs, and thus may play a role in assembly and/or budding of Ebola virus.
Harty Ronald N, Han Ziying
openaire +3 more sources
VLP purification and coupling of the E6 peptide.
, 2013 (a) 8% SDS-PAGE and corresponding western blot (b), probed with streptavidin-HRP, of purified RHDV-VLP and RHDV-VLP-PADRE uncoupled or coupled with the biotinylated E6 peptide.
Sara McKee (421996) +7 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечениеINTRODUCTION. Rotavirus vaccines based on virus-like particles (VLPs), non-infectious recombinant proteins of human rotavirus A that mimic the structure of the native virus, show promise for preventive vaccination.
I. E. Filatov +8 more
doaj +1 more source
3dcon: tomogram denoising by deconvolution. [PDF]
Acta Crystallogr D Struct BiolAn open‐source entropy‐regularized deconvolution workflow is presented for denoising tomographic reconstructions from cryo‐electron microscopy.Cryo‐electron tomography is an expanding technology for the study of macromolecules, viruses and cells.
Kirchweger P +3 more
europepmc +2 more sources
Selective cytotoxicity of GCV to SPBtk-VLP–infected A549 cells.
, 2016 The viability of human cells—IMR32, HK2, and A549—was assessed by the CCK-8 method 72 hours after various treatments. The treatment combinations included PBS followed by PBS (PBS/PBS), control VLPs followed by PBS (VLP/PBS), pUMVC1-tk–packaged VLPs ...
Chun-Nun Chao (2847461) +6 more
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source