Results 21 to 30 of about 23,750 (257)

VLPs and particle strategies for cancer vaccines [PDF]

Expert Review of Vaccines, 2013
Effective delivery of tumor antigens to APCs is one of the key steps for eliciting a strong and durable immune response to tumors. Several cancer vaccines have been evaluated in clinical trials, based on soluble peptides, but results have not been fully satisfactory.
UNGARO, FRANCESCA, CONTE, CLAUDIA, QUAGLIA, FABIANA, Maria Lina Tornesello, Franco M. Buonaguro, Luigi Buonaguro   +5 more
openaire   +4 more sources

VLP: A Survey on Vision-language Pre-training

Machine Intelligence Research, 2023
AbstractIn the past few years, the emergence of pre-training models has brought uni-modal fields such as computer vision (CV) and natural language processing (NLP) to a new era. Substantial works have shown that they are beneficial for downstream uni-modal tasks and avoid training a new model from scratch.
Feilong Chen, Duzhen Zhang, Minglun Han, Xiuyi Chen, Jing Shi 0003, Shuang Xu, Bo Xu 0002   +6 more
openaire   +2 more sources

Preparation of VLP nanoparticle, SARS-CoV-2 RBD, and VLP-based SARS-CoV-2 RBD vaccine.

, 2021
VLP nanoparticle (A), Fc-tagged SARS-CoV-2 RBD (B), and VLP-RBD complex (C) were each purified to high homogeneity. Left: representative elution profiles of the three proteins from Superose 6 Increase 10/300 GL high-resolution gel filtration ...
Jian Shang (1358481), Xiujuan Zhang (174319), Fang Li (41162), Sharon A. Taft-Benz (11402321), Chien-Te K. Tseng (492742), Marc Jenkins (11402327), Wanbo Tai (6535757), Elizabeth J. Anderson (7894313), Ralph S. Baric (7408220), Lanying Du (290113), Qibin Geng (3850708), Aleksandra Drelich (9143151), Victoria K. Baxter (11402318), Audrey C. Knight (11402324), Juan Shi (122591), Sarah R. Leist (7037384), Stephanie A. Montgomery (5797922), Kenneth H. Dinnon III (6482825), Mark Heise (67117), Sung-Wook Hong (592268), Yushun Wan (8551200)   +20 more
core   +1 more source

Simultaneous Immunization with Multivalent Norovirus VLPs Induces Better Protective Immune Responses to Norovirus than Sequential Immunization

Viruses, 2019
Human noroviruses (NoVs) are a genetically diverse, constantly evolving group of viruses. Here, we studied the effect of NoV pre-existing immunity on the success of NoV vaccinations with genetically close and distant genotypes.
Maria Malm, Timo Vesikari, Vesna Blazevic   +2 more
doaj   +1 more source

Quality Assessment of Virus-Like Particles at Single Particle Level: A Comparative Study

Viruses, 2020
Virus-like particles (VLPs) have emerged as a powerful scaffold for antigen presentation and delivery strategies. Compared to single protein-based therapeutics, quality assessment requires a higher degree of refinement due to the structure of VLPs and ...
Irene González-Domínguez, Eduard Puente-Massaguer, Laura Cervera, Francesc Gòdia   +3 more
doaj   +1 more source

Packaging of actin into Ebola virus VLPs [PDF]

Virology Journal, 2005
Abstract The actin cytoskeleton has been implicated in playing an important role assembly and budding of several RNA virus families including retroviruses and paramyxoviruses. In this report, we sought to determine whether actin is incorporated into Ebola VLPs, and thus may play a role in assembly and/or budding of Ebola virus.
Harty Ronald N, Han Ziying
openaire   +3 more sources

Vaccination with virus-like particles containing hemagglutinin protects the lungs of mice with postifluenza bacterial pneumonia: virological, microbiological and clinical data

Вопросы вирусологии, 2020
Introduction. Influenza is a severe viral disease, a frequent complication of which is a secondary bacterial pneumonia. Influenza vaccines prevent secondary bacterial complications.
I. N. Falynskova, A. Yu. Egorov, A. V. Poddubikov, N. O. Vartanova, N. P. Kartashova, E. A. Glubokova, V. A. Mkhitarov, D. S. Dzhalilova, O. V. Makarova, I. A. Leneva   +9 more
doaj   +1 more source

The safety of attenuated and recombinant nasal influenza vaccines in terms of the development of secondary bacterial superinfection

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Introduction. Influenza is a severe viral disease. The most common post-influenza complication is pneumonia. Earlier, we developed an experimental mouse model of viralbacterial pneumonia induced by successive infection with influenza virus and St. aureus,
N. R. Makhmudova, I. A. Leneva, N. V. Larionova, A. V. Poddubikov, I. N. Falynskova, N. P. Kartashova, O. A. Svitich   +6 more
doaj   +1 more source

Superior neutralizing antibody response and protection in mice vaccinated with heterologous DNA prime and virus like particle boost against HPAI H5N1 virus. [PDF]

PLoS ONE, 2011
BACKGROUND: Although DNA plasmid and virus-like particle (VLP) vaccines have been individually tested against highly pathogenic avian influenza (HPAI) H5N1 viruses, the combination of both vaccines into a heterologous prime-boost strategy against HPAI ...
Heng Ding, Cheguo Tsai, Ramona Alikiiteaga Gutiérrez, Fan Zhou, Philippe Buchy, Vincent Deubel, Paul Zhou   +6 more
doaj   +1 more source

Dry Formulation of Virus-Like Particles in Electrospun Nanofibers

Vaccines, 2021
Biologics can be combined with liquid polymer materials and electrospun to produce a dry nanofibrous scaffold. Unlike spray-drying and freeze-drying, electrospinning minimizes the physiological stress on sensitive materials, and nanofiber mat properties ...
Sasheen Dowlath, Katrin Campbell, Farah Al-Barwani, Vivienne L. Young, Sarah L. Young, Greg F. Walker, Vernon K. Ward   +6 more
doaj   +1 more source