How to fail with paired VNS therapy [PDF]
Vagus nerve stimulation (VNS) has gained enormous traction as a promising bioelectronic therapy. In particular, the delivery of VNS paired with training to promote neural changes has demonstrated clinical success for stroke recovery and found far ...
Seth A. Hays +2 more
doaj +3 more sources
Forward VNS, Reverse VNS, and Multi-VNS Algorithms for Job-Shop Scheduling Problem [PDF]
This paper proposes a number of forward VNS and reverse VNS algorithms for job-shop scheduling problem. The forward VNS algorithms are the variable neighborhood search algorithms applied to the original problem (i.e., the problem instance with the ...
Pisut Pongchairerks
doaj +3 more sources
A hybrid VNS matheuristic for a bin packing problem with a color constraint [PDF]
We study a new variant of the bin packing problem with a color constraint. Given a finite set of items, each item has a set of colors. Each bin has a color capacity, the total number of colors for a bin is the unification of colors for its items and ...
Kochetov Yury, Kondakov Arteam
doaj +1 more source
Neuroprotective effects of combined trimetazidine and progesterone on cerebral reperfusion injury
Cerebral ischemia-reperfusion injury induces multi-dimensional damage to neuronal cells through exacerbation of critical protective mechanisms.Targeting more than one mechanism simultaneously namely, inflammatory responses and metabolic energy ...
Vipin Dhote +5 more
doaj +1 more source
The experience of applying vagus nerve stimulation in treatment of pharmacoresistant epilepsy
The article presents a clinical case of adult patient with pharmacoresistant epilepsy lacking focal cerebral morphological changes, who was surgically implanted with a vagus nerve stimulation (VNS) system.
A. A. Shatokhin +5 more
doaj +1 more source
Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]
Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
Berfelo, M. W. +6 more
core +10 more sources
Reducing VNS stimulation parameters: Is it safe?
Introduction Vagal nerve stimulation (VNS) is an adjuvant therapy used in the treatment of patients with refractory epilepsy who are not candidates for resective surgery or who have limited results after surgical procedures.
Tatiana Von Hertwig Fernandes de Oliveira +4 more
doaj +1 more source
Neurophysiological investigations of drug resistant epilepsy patients treated with vagus nerve stimulation to differentiate responders from non-responders [PDF]
Background and purpose In patients treated with vagus nerve stimulation (VNS) for drug resistant epilepsy (DRE), up to a third of patients will eventually not respond to the therapy.
Boon, Paul +13 more
core +2 more sources
Objective: The effectiveness of vagus nerve stimulation (VNS) for residual seizures after corpus callosotomy (CC) has not yet been fully investigated. We hypothesized that seizure control would be improved by VNS after CC.
Keisuke Hatano +4 more
doaj +1 more source
Stochastic vagus nerve stimulation affects acute heart rate dynamics in rats. [PDF]
Vagus nerve stimulation (VNS) is an approved therapy for treatment of epilepsy and depression. While also shown to be promising in several preclinical and clinical studies to treat cardiovascular diseases, optimal therapeutic stimulation paradigms are ...
Steven W Lee +5 more
doaj +1 more source

