Results 211 to 220 of about 8,582,680 (279)

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez   +6 more
wiley   +1 more source

Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley   +1 more source

Direct Self-Injurious Behavior (D-SIB) and Life Events among Vocational School and High School Students. [PDF]

open access: yesInt J Environ Res Public Health, 2018
Horváth LO   +15 more
europepmc   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol   +4 more
wiley   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay   +4 more
wiley   +1 more source

The Impact of Mindfulness as a Session‐Introduction on Symptoms and Alliance in Individual Cognitive‐Behavioral Therapy With Children and Adolescents: A Randomized Controlled Trial

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Mindfulness is increasingly being implemented in child and adolescent therapy. However, little is known about its effectiveness in individual settings within a clinical outpatient context. We investigated the effects of session‐introducing mindfulness interventions (IG‐M) compared to session‐introducing relaxation interventions (CG ...
Julia Kalmar   +8 more
wiley   +1 more source

Positive developmental cascades: Strength development reduces support needs in children

open access: yesJCPP Advances, EarlyView.
Abstract Background Strength development in children across a range of psychiatric diagnoses may reduce needs for mental health, social, and functioning support over time. A strength‐based adjunct to child and adolescent mental health may foster the developmental context most helpful for achieving desired outcomes with positive developmental cascading ...
Melody R. Altschuler   +12 more
wiley   +1 more source

Differences in associations between attention‐deficit hyperactivity disorder symptoms and physical activity across childhood and adolescence and among males and females in a representative UK birth cohort

open access: yesJCPP Advances, EarlyView.
Abstract Background Children and adolescents with attention‐deficit hyperactivity disorder (ADHD) exhibit higher physical activity (PA) levels than peers without ADHD. It remains unclear how this association evolves across developmental stages and differs between sexes.
Amandine Sénéquier   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy