Results 1 to 10 of about 926,555 (202)

“Hey Siri, Help Me Take Care of My Child”: A Feasibility Study With Caregivers of Children With Special Healthcare Needs Using Voice Interaction and Automatic Speech Recognition in Remote Care Management [PDF]

Frontiers in Public Health, 2022
BackgroundAbout 23% of households in the United States have at least one child who has special healthcare needs. As most care activities occur at home, there is often a disconnect and lack of communication between families, home care nurses, and ...
Emre Sezgin, Brannon Oiler, Brandon Abbott, Garey Noritz, Yungui Huang   +4 more
doaj   +2 more sources

A brain metastasis model for breast cancer using human embryonic stem cell-derived cerebral organoids [PDF]

Organoid, 2022
Background Breast cancer is a common cause of brain metastasis. Although breast cancer has relatively high survival rates, its survival rate after metastasis to the brain is lower.
Mu Seog Choe, Min Young Lee
doaj   +1 more source

Insights into the inhibitory activities of neolignans and diarylnonanoid derivatives from nutmeg (Myristica fragrans Houtt.) seeds on soluble epoxide hydrolase using in vitro and in silico approaches

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Two new neolignans, myrifralignans F–G (14 and 18), four new diarylnonanoid derivatives, myrifragranones A–D (21–24), and 18 known compounds were isolated and structurally elucidated from nutmeg (Myristica fragrans Houtt.) seeds.
Vu Thi Oanh, Nguyen Viet Phong, Byung Sun Min, Seo Young Yang, Jeong Ah Kim   +4 more
doaj   +1 more source

Inhibitory Effect of Coumarins and Isocoumarins Isolated from the Stems and Branches of Acer mono Maxim. against Escherichia coli β-Glucuronidase

Applied Sciences, 2022
We isolated eight known secondary metabolites, including two isocoumarins and six coumarins, from the stems and branches of Acer mono Maxim. Their structures were confirmed using nuclear magnetic resonance spectroscopy and by comparing the data to ...
Nguyen Viet Phong, Byung Sun Min, Seo Young Yang, Jeong Ah Kim   +3 more
doaj   +1 more source

A simple method to improve the quality and yield of human pluripotent stem cell-derived cerebral organoids

Heliyon, 2021
The development of cerebral organoid technology has allowed the human neural tissue to be collected for studying human brain development and neurological diseases. Human pluripotent stem cell-derived cerebral organoids (hCOs) are a theoretically infinite
Mu Seog Choe, So Jin Kim, Seung Taek Oh, Chang Min Bae, Won-Young Choi, Kyung Min Baek, Joong Sun Kim, Min Young Lee   +7 more
doaj   +1 more source

RUNX Family in Hypoxic Microenvironment and Angiogenesis in Cancers

Cells, 2022
The tumor microenvironment (TME) is broadly implicated in tumorigenesis, as tumor cells interact with surrounding cells to influence the development and progression of the tumor.
You Mie Lee
doaj   +1 more source

Effect of Lactic Acid Bacteria on the Pharmacokinetics and Metabolism of Ginsenosides in Mice

Pharmaceutics, 2021
This study aims to investigate the effect of lactic acid bacteria (LAB) on in vitro and in vivo metabolism and the pharmacokinetics of ginsenosides in mice.
Ji-Hyeon Jeon, Jaehyeok Lee, Jin-Hyang Park, Chul-Haeng Lee, Min-Koo Choi, Im-Sook Song   +5 more
doaj   +1 more source

Voice-mediated interactions in a megaherbivore [PDF]

Current Biology, 2022
Planet Earth is becoming increasingly difficult for large animal species to inhabit. Yet, these species are of major importance for the functioning of the biosphere and their progressive disappearance is accompanied by profound negative alterations of ecosystems1 (Supplemental information).
Thévenet, Julie, Grimault, Nicolas, Fonseca, Paulo, Mathevon, Nicolas   +3 more
openaire   +5 more sources

Inhibitory Activity of Bioactive Phloroglucinols from the Rhizomes of Dryopteris crassirhizoma on Escherichia coli β-Glucuronidase: Kinetic Analysis and Molecular Docking Studies

Metabolites, 2022
Phloroglucinols—one of the major secondary metabolites in Dryopteris crassirhizoma—exhibit various pharmacological effects, such as antiviral, antioxidant, and antidiabetic activities. This study evaluated 30 phloroglucinols isolated from the rhizomes of
Nguyen Viet Phong, Yan Zhao, Byung Sun Min, Seo Young Yang, Jeong Ah Kim   +4 more
doaj   +1 more source

Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance

Pharmaceutics, 2021
Candesartan cilexetil (CC), a prodrug and highly effective antihypertensive agent, is a poorly soluble (BCS Class II) drug with limited bioavailability.
Surendra Poudel, Dong Wuk Kim
doaj   +1 more source