Results 21 to 30 of about 4,034,693 (236)

Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan

open access: yesPharmaceuticals, 2021
Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility.
Bhupendra Raj Giri   +5 more
doaj   +1 more source

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats

open access: yesPharmaceutics, 2022
This study investigated the pharmacokinetics and tissue distribution of enavogliflozin, a novel sodium-glucose cotransporter 2 inhibitor that is currently in phase three clinical trials.
Minyeong Pang   +6 more
doaj   +1 more source

Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions

open access: yesPharmaceutics, 2021
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
doaj   +1 more source

Improved Hygroscopicity and Bioavailability of Solid Dispersion of Red Ginseng Extract with Silicon Dioxide

open access: yesPharmaceutics, 2021
This study aims to develop a powder formulation for the Korean red ginseng extract (RGE) and to evaluate its in vitro and in vivo formulation characteristics. The solid dispersion of RGE was prepared with hydrophilic carriers using a freeze-drying method.
Sojeong Jin   +6 more
doaj   +1 more source

Research and Application of Voice Technology in Mine Transport Vehicles

open access: yesKongzhi Yu Xinxi Jishu, 2023
In order to develop more intelligent transport vehicles for surface mines to enable the drivers work more efficiently and safely, this paper puts forward a solution of applying voice technology to the cab of mine transport vehicle and ground command ...
LIU Yue   +4 more
doaj   +3 more sources

Improved Bioavailability and High Photostability of Methotrexate by Spray-Dried Surface-Attached Solid Dispersion with an Aqueous Medium

open access: yesPharmaceutics, 2021
Low aqueous solubility and poor bioavailability are major concerns in the development of oral solid-dosage drug forms. In this study, we fabricated surface-attached solid dispersion (SASD) to enhance the solubility, bioavailability, and photostability of
Bhupendra Raj Giri   +7 more
doaj   +1 more source

The design of intelligent Magic Mirror based on Raspberry Pi

open access: yesDianzi Jishu Yingyong, 2021
With the development of the Internet of Things technology, the field of smart home has risen rapidly, and has bright prospects for development. The design and implementation of the intelligent Magic Mirror system in the smart home industry is designed to
Pan Zhiqian
doaj   +1 more source

Research of Speech Recognition Algorithm Based on Time Delay Neural Network and Its Application in Rail Transit

open access: yesKongzhi Yu Xinxi Jishu, 2022
Speech recognition technology is a key component of the intelligent voice interaction system. In recent years, this technology has developed rapidly and is widely used in automotive electronics, consumer electronics, medical and other fields.
LIU Yue   +4 more
doaj   +3 more sources

Phytochemical constituents of Hydrangea macrophylla var. acuminata leaves and their inhibitory activity against PTP1B and α-glucosidase

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
This study presents the first comprehensive phytochemical analysis of Hydrangea macrophylla var. acuminata leaves, resulting in the isolation of 41 secondary metabolites, including four new compounds: one phenolic (3) and three bis-iridoid glycosides (30–
Thi Ly Pham   +4 more
doaj   +1 more source

Modeling Synucleinopathy Using hESC-Derived Cerebral Organoids

open access: yesCells
Animal and cellular models harboring SNCA gene mutations have been instrumental in synucleinopathy, but faithful human brain models remain limited. Here, we report the development of a human cerebral organoid (CO) model of synucleinopathy carrying the ...
So Jin Kim   +4 more
doaj   +1 more source

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