Results 11 to 20 of about 92,080 (309)

Frame Analysis of Voice Interaction Gameplay [PDF]

Proceedings of the 2019 CHI Conference on Human Factors in Computing Systems, 2019
Voice control is an increasingly common feature of digital games, but the experience of playing with voice control is often hampered by feelings of embarrassment and dissonance. Past research has recognised these tensions, but has not offered a general model of how they arise and how players respond to them. In this study, we use Erving Goffman's frame
Fraser Allison, Joshua Newn, Wally Smith, Marcus Carter, Martin R. Gibbs   +4 more
core   +3 more sources

Design Patterns for Voice Interaction in Games [PDF]

Proceedings of the 2018 Annual Symposium on Computer-Human Interaction in Play, 2018
Voice interaction is increasingly common in digital games, but it remains a notoriously difficult modality to design a satisfying experience for. This is partly due to limitations of speech recognition technology, and partly due to the inherent awkwardness we feel when performing some voice actions.
Fraser Allison, Marcus Carter, Martin R. Gibbs, Wally Smith   +3 more
openaire   +2 more sources

Inhibitory Activity of Bioactive Phloroglucinols from the Rhizomes of Dryopteris crassirhizoma on Escherichia coli β-Glucuronidase: Kinetic Analysis and Molecular Docking Studies

Metabolites, 2022
Phloroglucinols—one of the major secondary metabolites in Dryopteris crassirhizoma—exhibit various pharmacological effects, such as antiviral, antioxidant, and antidiabetic activities. This study evaluated 30 phloroglucinols isolated from the rhizomes of
Nguyen Viet Phong, Yan Zhao, Byung Sun Min, Seo Young Yang, Jeong Ah Kim   +4 more
doaj   +1 more source

Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance

Pharmaceutics, 2021
Candesartan cilexetil (CC), a prodrug and highly effective antihypertensive agent, is a poorly soluble (BCS Class II) drug with limited bioavailability.
Surendra Poudel, Dong Wuk Kim
doaj   +1 more source

Simultaneous Analysis of a Combination of Anti-Hypertensive Drugs, Fimasartan, Amlodipine, and Hydrochlorothiazide, in Rats Using LC-MS/MS and Subsequent Application to Pharmacokinetic Drug Interaction with Red Ginseng Extract

Toxics, 2022
Fimasartan, amlodipine, and hydrochlorothiazide are commonly used in combination therapies as antihypertensive drugs. This study aimed to develop and validate an analytical method for fimasartan, its active and major metabolite fimasartan-amide ...
So-Yeon Jeon, Ji-Hyeon Jeon, Jin-Hyang Park, Jihoon Lee, Minyeong Pang, Min-Koo Choi, Im-Sook Song   +6 more
doaj   +1 more source

Optimization of Ultrasonic-Assisted Extraction of α-Glucosidase Inhibitors from Dryopteris crassirhizoma Using Artificial Neural Network and Response Surface Methodology

Metabolites, 2023
Dryopteris crassirhizoma Nakai is a plant with significant medicinal properties, such as anticancer, antioxidant, and anti-inflammatory activities, making it an attractive research target.
Nguyen Viet Phong, Dan Gao, Jeong Ah Kim, Seo Young Yang   +3 more
doaj   +1 more source

Enhanced Bioavailability and Efficacy of Silymarin Solid Dispersion in Rats with Acetaminophen-Induced Hepatotoxicity

Pharmaceutics, 2021
We evaluated the bioavailability, liver distribution, and efficacy of silymarin-D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) solid dispersion (silymarin-SD) in rats with acetaminophen-induced hepatotoxicity (APAP) compared with silymarin ...
Im-Sook Song, So-Jeong Nam, Ji-Hyeon Jeon, Soo-Jin Park, Min-Koo Choi   +4 more
doaj   +1 more source

Fabrication of Gastro-Floating Famotidine Tablets: Hydroxypropyl Methylcellulose-Based Semisolid Extrusion 3D Printing

Pharmaceutics, 2023
Semisolid extrusion (SSE) three-dimensional (3D) printing uses drug-loaded paste for the printing process, which is capable of constructing intricate 3D structures.
Hyun Seok Yang, Dong Wuk Kim
doaj   +1 more source

Alternative Methotrexate Oral Formulation: Enhanced Aqueous Solubility, Bioavailability, Photostability, and Permeability

Pharmaceutics, 2022
The poor aqueous solubility and/or permeability and thereby limited bioavailability largely restricts the pharmaco-therapeutic implications of potent anticancer drugs such as methotrexate (MTX).
Bhupendra Raj Giri, Hyun Seok Yang, Im-Sook Song, Han-Gon Choi, Jung Hyun Cho, Dong Wuk Kim   +5 more
doaj   +1 more source

Enhancing Dissolution and Oral Bioavailability of Ursodeoxycholic Acid with a Spray-Dried pH-Modified Extended Release Formulation

Pharmaceutics, 2022
Ursodeoxycholate (UDCA) has low oral bioavailability and pH-dependent solubility and permeability. Thus, we developed a pH-modified extended-release formulation of UDCA using Na2CO3 as the alkalizing agent and hydroxypropyl methylcellulose (HPMC) as the ...
Jaehyeok Lee, Chul Haeng Lee, Jong-Geon Lee, So Yeon Jeon, Min-Koo Choi, Im-Sook Song   +5 more
doaj   +1 more source