Results 101 to 110 of about 681,564 (359)

B cells and systemic sclerosis interstitial lung disease

Arthritis &Rheumatology, Accepted Article.
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman, Voon Ong, Christopher Denton   +2 more
wiley   +1 more source

Development of a simple method for differential delivery of volatile anesthetics to the spinal cord of the rabbit.

PLoS ONE, 2020
Emulsified volatile anesthetic can be directly injected into the circulation and eliminated from blood through lungs. Taking advantage of the unique pharmacokinetics of the emulsified volatile anesthetics, we aimed to develop a less traumatic method to ...
Peng Zhang, Yao Li, Ting Xu
doaj   +1 more source

Phase transitions in biological membranes

, 2018
Native membranes of biological cells display melting transitions of their lipids at a temperature of 10-20 degrees below body temperature. Such transitions can be observed in various bacterial cells, in nerves, in cancer cells, but also in lung ...
A Blicher, A Blicher, A Gonzalez-Perez, A Gonzalez-Perez, A Hac, A Punnia-Moorthy, AG Lee, AL Hodgkin, AL Hodgkin, B Lautrup, D Johnston, D Papahadjopoulos, DB Mountcastle, DP Kharakoz, E London, EF DeLong, FH Johnson, FH Johnson, GH Kim, GS Manning, H Ebel, H Kamaya, H Kamaya, H Kamaya, H Träuble, HJ Galla, HM Seeger, HM Seeger, I Tasaki, J Gallaher, J Marmur, JE Rothman, JE Rothman, JLCM Vossenberg van de, JM Ritchie, JR Hazel, JR Hazel, JR Trudell, K Græsbøll, K Iwasa, K Iwasa, K Simons, KA Zecchi, KR Laub, L Onsager, LD Mosgaard, LD Mosgaard, LO Ingram, M Gudmand, M Moldovan, MC Sabra, MJ Halsey, MJ Pringle, OG Mouritsen, P Grabitz, PF Almeida, PL Privalov, R Böckmann, R Ravindra, R Winter, RS Cantor, RS Cantor, RW Glaser, S Johnson, SV Avery, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Heimburg, T Horishita, Tian Wang, UR Pedersen, Y Kaminoh, Y Zuo   +76 more
core   +1 more source

Pharmacogenomics in clinical practice: Biomarker information in Brazilian drug labels

British Journal of Clinical Pharmacology, EarlyView.
This review examines the PGx annotations in package inserts (bulas in Brazilian Portuguese) approved by ANVISA, the Brazilian Health Regulatory Agency, for 19 gene–drug pairs with strong or moderate recommendations for initial dosing alteration in the CPIC (Clinical Pharmacogenetic Implementation Consortion) guidelines and PGx testing required or ...
Guilherme Suarez‐Kurtz
wiley   +1 more source

Intra and postoperative outcome of adding clonidine to bupivacaine in infraorbital nerve block for young children undergoing cleft lip surgery

Saudi Journal of Anaesthesia, 2011
Aims and Context: To evaluate the efficacy of adding clonidine to bupivacaine in bilateral infraorbital nerve block for hemodynamic changes, requirement of opioids, volatile agent, and muscle relaxants intraoperatively and relief of pain postoperatively .
Parul Jindal, Gurjeet Khurana, Sanjay Dvivedi, J P Sharma   +3 more
doaj   +1 more source

Stimulus Threshold for Providing Intraoperative Motor Evoked Potential

Haseki Tıp Bülteni, 2020
Aim:Intraoperative neurophysiological monitoring (IOM) has been increasingly used in surgeries associated with a risk of neurological impairment. Motor evoked potential (MEP), which is a part of intraoperative neurophysiological tests, evaluates motor ...
Emine Taşkıran, Dilek Akyüz
doaj   +1 more source

Hormonal basis of sex differences in anesthetic sensitivity

Proceedings of the National Academy of Sciences of the United States of America
Significance Half of all surgical patients receiving anesthesia are females. Anesthetics affect sexually dimorphic brain regions involved in sleep and arousal.
Andrzej Z. Wasilczuk, Cole Rinehart, Adeeti Aggarwal, Martha E. Stone, G. Mashour, M. Avidan, Max B. Kelz, A. Proekt   +7 more
semanticscholar   +1 more source

Secondary Metabolites Composition and Their Histochemical Localization in the Fruit of Piper malgassicum Papini, Palchetti, Gori and Rota Nodari (Piperaceae)

Chemistry &Biodiversity, EarlyView.
ABSTRACT The anatomy, histochemistry, and secondary metabolite composition were investigated on the drupes of Piper malgassicum, one of the components of the spice voatsiperifery pepper. The high amount of piperine recorded with high‐performance liquid chromatography with photodiode‐array detection analysis was localized with histochemistry mainly ...
Sara Falsini, Sara Ballantini, Alexander Pittella, Gelsomina Fico, Claudia Giuliani, Enrico Palchetti, Massimo Gori, Stefano Biricolti, Emilio Corti, Alessio Papini, Luca Calamai, Marzia Innocenti   +11 more
wiley   +1 more source

The use of a volatile anesthetic regimen protects against acute normovolemic hemodilution induced myocardial depression in patients with coronary artery disease

Asian Journal of Transfusion Science, 2009
Background: Previous studies indicated that acute normovolemic hemodilution (ANH) was associated with a depression of myocardial function in coronary surgery patients with baseline heart rate faster than 90 bpm.
Lorsomradee Sratwadee, Lorsomradee Suraphong   +1 more
doaj  

Computational Predictions of Volatile Anesthetic Interactions with the Microtubule Cytoskeleton: Implications for Side Effects of General Anesthesia

PLoS ONE, 2012
The cytoskeleton is essential to cell morphology, cargo trafficking, and cell division. As the neuronal cytoskeleton is extremely complex, it is no wonder that a startling number of neurodegenerative disorders (including but not limited to Alzheimer’s ...
T. Craddock, M. St. George, H. Freedman, K. Barakat, Sambasivarao Damaraju, S. Hameroff, J. Tuszynski   +6 more
semanticscholar   +1 more source