Surgical site infection after colorectal surgery according to the main anesthetic agent: a retrospective comparison between volatile anesthetics and propofol [PDF]
BackgroundAnesthetic agents used for general anesthesia are emerging possible influential factors for surgical site infection (SSI). In this retrospective study, we evaluated the incidence of SSI after colorectal surgery according to the main anesthetic ...
Bon-Wook Koo+6 more
doaj +2 more sources
A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj +2 more sources
Volatile Anesthetic Sevoflurane Attenuates Toll-Like Receptor 1/2 Activation. [PDF]
BACKGROUND: Although immunomodulatory effects of anesthetics have been increasingly recognized, their underlying molecular mechanisms are not completely understood. Toll-like receptors (TLRs) are one of the major receptors to recognize invading pathogens
Mitsui Y+5 more
europepmc +2 more sources
Use of Remifentanil for Open in utero Fetal Myelomeningocele Repair Maintains Uterine Relaxation with Reduced Volatile Anesthetic Concentration. [PDF]
Introduction: Open fetal repair of myelomeningocele (MMC) is an option for prenatally diagnosed spina bifida. Historically, high-dose volatile anesthetic was used for uterine relaxation but is associated with fetal cardiovascular depression.
Marsh BJ+4 more
europepmc +2 more sources
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for the Use of Potent Volatile Anesthetic Agents and Succinylcholine in the Context of RYR1 or CACNA1S Genotypes. [PDF]
The identification in a patient of 1 of the 50 variants in the RYR1 or CACNA1S genes reviewed here should lead to a presumption of malignant hyperthermia susceptibility (MHS).
Gonsalves SG+14 more
europepmc +2 more sources
Sepsis remains a significant health care burden, with high morbidities and mortalities. Patients with sepsis often require general anesthesia for procedures and imaging studies. Knowing that anesthetic drugs can pose immunomodulatory effects, it would be
Koutsogiannaki S+7 more
europepmc +2 more sources
BACKGROUND Delayed neurocognitive recovery after surgery is associated with poor outcome. Most surgeries require general anesthesia, of which sevoflurane and propofol are the most commonly used inhalational and intravenous anesthetics. The authors tested
Yujuan Li+19 more
semanticscholar +1 more source
The Impact of Volatile Anesthetic Choice on Postoperative Outcomes of Cardiac Surgery: A Meta-Analysis. [PDF]
Objectives To evaluate the impact of volatile anesthetic choice on clinically relevant outcomes of patients undergoing cardiac surgery. Methods Major databases were systematically searched for randomized controlled trials (RCTs) comparing volatile ...
Zorrilla-Vaca A+3 more
europepmc +2 more sources
The method of automatical adjustment controlled maintenance of the surgical stage of anesthesia of patient during general anesthesia by means of volatile anesthetic dosage regulation depending on BIS level is described and explained.
A. A. Satsishur
doaj +1 more source
Mechanism underlying sevoflurane-induced protection in cerebral ischemia–reperfusion injury
Cerebral ischemia is an extremely complex disease that can be caused by a variety of factors. Cerebral ischemia can cause great harm to human body. Sevoflurane is a volatile anesthetic that is frequently used in clinic, and has a lot of advantages, such ...
Chen Bing+5 more
doaj +1 more source