Sodium Channels as Targets for Volatile Anesthetics [PDF]
Frontiers in Pharmacology, 2012 The molecular mechanisms of modern inhaled anesthetics are still poorly understood although they are widely used in clinical settings. Considerable evidence supports effects on membrane proteins including ligand- and voltage-gated ion channels of excitable cells.
Herold, Karl F., Hemmings Jr., Hugh C.
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The neuroendocrine stress response compensates for suppression of insulin secretion by volatile anesthetic agents: An observational study. [PDF]
Physiol Rep, 2023 Alterations in perioperative metabolic function, particularly hyperglycemia, are associated with increased post‐operative complications, even in patients without preexisting metabolic abnormalities.
Tharp WG +4 more
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Use of remimazolam as an adjunct to general anesthesia for an adolescent with MELAS syndrome. [PDF]
Pediatric Anesthesia and Critical Care Journal (PACCJ), 2022 MELAS syndrome is an acronym so named because of the characteristic clinical and pathophysiologic features including mitochondrial encephalo-myopathy, lactic aci- dosis, and stroke-like episodes.
N. Gyurgyik +3 more
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Mechanistic insights into volatile anesthetic modulation of K2P channels. [PDF]
Elife, 2020 K2P potassium channels are known to be modulated by volatile anesthetic (VA) drugs and play important roles in clinically relevant effects that accompany general anesthesia.
Wague A +9 more
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Frontiers in Cardiovascular Medicine, 2023 BackgroundStudies investigating the cardioprotective effect of volatile anesthetics on cardiac troponins in off-pump coronary artery bypass grafting (OPCAB) surgery remain controversial.
Chenghong Zhang +6 more
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Доклады Белорусского государственного университета информатики и радиоэлектроники, 2020 The method of automatical adjustment controlled maintenance of the surgical stage of anesthesia of patient during general anesthesia by means of volatile anesthetic dosage regulation depending on BIS level is described and explained.
A. A. Satsishur
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Surgical site infection after colorectal surgery according to the main anesthetic agent: a retrospective comparison between volatile anesthetics and propofol [PDF]
Korean Journal of Anesthesiology, 2016 BackgroundAnesthetic agents used for general anesthesia are emerging possible influential factors for surgical site infection (SSI). In this retrospective study, we evaluated the incidence of SSI after colorectal surgery according to the main anesthetic ...
Bon-Wook Koo +6 more
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Volatile Anesthetics and Immunity [PDF]
Immunological Investigations, 2017 Historically, volatile anesthetics have demonstrated interesting interactions with both the innate and adaptive immune systems. This review organizes these interactions into four phases: recognition, recruitment, response, and resolution. These phases represent a range of proinflammatory, inflammatory, and innate and adaptive immune regulatory ...
Siavash, Sedghi +3 more
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Mechanism underlying sevoflurane-induced protection in cerebral ischemia–reperfusion injury
Open Chemistry, 2021 Cerebral ischemia is an extremely complex disease that can be caused by a variety of factors. Cerebral ischemia can cause great harm to human body. Sevoflurane is a volatile anesthetic that is frequently used in clinic, and has a lot of advantages, such ...
Chen Bing +5 more
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Cancerous phenotypes associated with hypoxia-inducible factors are not influenced by the volatile anesthetic isoflurane in renal cell carcinoma. [PDF]
PLoS One, 2019 The possibility that anesthesia during cancer surgery may affect cancer recurrence, metastasis, and patient prognosis has become one of the most important topics of interest in cancer treatment.
Sumi C +7 more
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