Results 21 to 30 of about 660,206 (287)

Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors.

open access: yesFASEB J, 2018
Woll KA   +6 more
europepmc   +2 more sources

C. elegans and volatile anesthetics [PDF]

open access: yesWormBook, 2007
The mechanism of action of volatile anesthetics remains an enigma, despite their worldwide use. The nematode C. elegans has served as an excellent model to unravel this mystery. Genes and gene sets that control the behavior of the animal in volatile anesthetics have been identified, using multiple endpoints to mimic the phenomenon of anesthesia in man.
Ernst Bernhard Kayser   +2 more
openaire   +3 more sources

From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. [PDF]

open access: yesToxicol Sci, 2017
Koutsogiannaki S   +8 more
europepmc   +2 more sources

Immune Modulation by Volatile Anesthetics [PDF]

open access: yesAnesthesiology, 2016
Abstract Volatile general anesthetics continue to be an important part of clinical anesthesia worldwide. The impact of volatile anesthetics on the immune system has been investigated at both mechanistic and clinical levels, but previous studies have returned conflicting findings due to varied protocols, experimental environments, and subject ...
Binfeng Lu   +5 more
openaire   +2 more sources

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the ILAE/AES joint translational TASK force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila   +11 more
wiley   +1 more source

Changes in Alpha Frequency and Power of the Electroencephalogram during Volatile-Based General Anesthesia

open access: yesFrontiers in Systems Neuroscience, 2017
Oscillations in the electroencephalogram (EEG) at the alpha frequency (8–12 Hz) are thought to be ubiquitous during surgical anesthesia, but the details of how this oscillation responds to ongoing changes in volatile anesthetic concentration have not ...
Darren Hight   +6 more
doaj   +1 more source

The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study.

open access: yesPLoS ONE, 2021
BackgroundTo determine whether the anesthetic method of propofol total intravenous anesthesia (TIVA) is associated with postoperative outcome in ESRD patients, we evaluated the incidence of postoperative major adverse cardiac events (MACE), comparing ...
Ho Bum Cho   +9 more
doaj   +1 more source

Ultrasound-Assisted Thoracic Paravertebral Block Reduces Intraoperative Opioid Requirement and Improves Analgesia after Breast Cancer Surgery: A Randomized, Controlled, Single-Center Trial. [PDF]

open access: yesPLoS ONE, 2015
The contribution of ultrasound-assisted thoracic paravertebral block to postoperative analgesia remains unclear. We compared the effect of a combination of ultrasound assisted-thoracic paravertebral block and propofol general anesthesia with opioid and ...
Lijian Pei   +14 more
doaj   +1 more source

Volatile anesthetics as a neuroprotective agent [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
Pharmacologic protection of brain from ischemic insult has been intensively investigated since the early 1960s [1] and a considerable amount of work has been performed to show the effectiveness of various drugs. Among these studies, anesthetic agents, including intravenous and volatile drugs, were shown to be promising agents.
openaire   +4 more sources

Are volatile anesthetics neuroprotective or neurotoxic? [PDF]

open access: yesMedical Gas Research, 2012
Volatile anesthetics are one class of the most commonly used drugs. However, the mechanisms for these drugs to induce anesthesia are not fully understood and have been under intensive investigation. Two other effects of these anesthetics on the central nervous system, volatile anesthetics-induced neuroprotection and neurotoxicity, currently are hot ...
openaire   +2 more sources

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