Results 31 to 40 of about 10,420 (164)

Development of NMDA receptors contributes to the enhancement of electroencephalogram oscillations under volatile anesthetics in rats

Frontiers in Neural Circuits, 2022
BackgroundVolatile anesthetics including sevoflurane and isoflurane enhance oscillations of cortical electroencephalogram (EEG), partly by their modulations on glutamate-mediated excitatory synaptic transmission. Expression of NMDA receptors is increased
Mingyue Zhang, Mingyue Zhang, Yali Chen, Yali Chen, Jin Liu, Jin Liu, Yaoxin Yang, Yaoxin Yang, Rurong Wang, Donghang Zhang, Donghang Zhang, Tao Zhu   +11 more
doaj   +1 more source

Volatile anesthetics alter protein stability

Toxicology Letters, 1998
1. We have used differential scanning calorimetry to measure the halothane induced change in stability of five lipid-free proteins in aqueous solution. 2. The temperature at peak heat capacity (Tm) as the sample is heated provides a measure of stability. 3.
J W, Tanner, P A, Liebman, R G, Eckenhoff   +2 more
openaire   +2 more sources

Dexmedetomidine as the primary anesthetic agent during cardiac surgery in an infant with a family history of malignant hyperthermia

Saudi Journal of Anaesthesia, 2011
Malignant hyperthermia (MH) is an acute hypermetabolic crisis triggered in susceptible patients by the administration of succinylcholine or a volatile anesthetic agent.
Aymen Naguib, Chris McKee, Alistair Phillips, Joseph D Tobias   +3 more
doaj   +1 more source

Impact of General Anesthetics on Postoperative Infections-A Narrative Review. [PDF]

Life (Basel)
Postoperative infections represent the most frequent complication after surgery. Anesthetic agents, while essential during surgical procedures to ensure unconsciousness, are becoming increasingly recognized as modulators of immune function.
Butt TPL, Jazzar L, Watts P, Lehmann C.
europepmc   +2 more sources

Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde

Scandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an indicator of increased cancer risk.
Ludovit Musak, Zdenek Smerhovsky, Erika Halasova, Oto Osina, Lucia Letkova, Ludmila Vodickova, Veronika Polakova, Janka Buchancova, Kari Hemminki, Pavel Vodicka   +9 more
doaj   +1 more source

An innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit

Annals of Cardiac Anaesthesia, 2017
Context: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist ...
Francesco De Simone, Luigi Cassarà, Salvatore Sardo, Elena Scarparo, Omar Saleh, Caetano Nigro Neto, Alberto Zangrillo, Giovanni Landoni   +7 more
doaj   +1 more source

Neurotoxic Impact of Individual Anesthetic Agents on the Developing Brain

Children, 2022
Concerns about the safety of anesthetic agents in children arose after animal studies revealed disruptions in neurodevelopment after exposure to commonly used anesthetic drugs.
Dabin Ji, Joelle Karlik
doaj   +1 more source

Volatile anesthetics affect macrophage phagocytosis

PLOS ONE, 2019
Perioperative infections, particularly surgical site infections pose significant morbidity and mortality. Phagocytosis is a critical step for microbial eradication. We examined the effect of commonly used anesthetics on macrophage phagocytosis and its mechanism.The effect of anesthetics (isoflurane, sevoflurane, propofol) on macrophage phagocytosis was
Hui Zha, Erika Matsunami, Nathan Blazon-Brown, Sophia Koutsogiannaki, Lifei Hou, Weiming Bu, Hasan Babazada, Kirsten C. Odegard, Renyu Liu, Roderic G. Eckenhoff, Koichi Yuki   +10 more
openaire   +3 more sources

An observational laboratory study to evaluate an anesthetic gas adsorber without anesthetic gas scavenging system

BMC Anesthesiology
Background Volatile anesthetics are known to be potent greenhouse gases and a significant source of per-and polyfluoroalkyl substances (PFAS) “forever chemical” pollution.
Katja Nickel, Christian Thoben, Christiane E. Beck, Jan Karsten, Terence Krauß, Alexander Nitschke, Moritz Hitzemann, Stefan Zimmermann, Sebastian Heiderich   +8 more
doaj   +1 more source

Anesthetic Considerations in a Patient with Myotonic Dystrophy for Hip Labral Repair

Case Reports in Anesthesiology, 2017
Myotonic Dystrophy (DM) affects multiple organ systems. Disorders such as hyperthyroidism, progressive musculoskeletal weakness, cardiac dysrhythmias, hypoventilation, and cognitive-behavioral disorders may be present in these patients.
Ramon Go, David Wang, Danielle Ludwin
doaj   +1 more source