Results 51 to 60 of about 660,206 (287)

Prospects of cardioprotection by volatile anesthetics

open access: yesMedicinski pregled, 2010
Myocardial ischaemia is followed by some reversibile or ireversibile changes. The aim of cardioplegia is to protect numerous intracellular processes: to spare the intracellular energy stores, to reduce the free oxygen radicals synthesis, to protect the function of the endothelium and myocardial oxygen balance as well as ionic balance.
Borislav Krivokapić   +5 more
openaire   +4 more sources

Inhibition of mitochondrial respiration by general anesthetic drugs

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology, 2022
General anesthetic drugs have been associated with various unwanted effects including an interference with mitochondrial function. We had previously observed increases of lactate formation in the mouse brain during anesthesia with volatile anesthetic ...
Anton Fedorov, A. Lehto, J. Klein
semanticscholar   +1 more source

Rapid and Scalable Lubrication Coating for Industrial and Medical Applications via Sequential Dip‐Coating

open access: yesAdvanced Materials Interfaces, EarlyView.
This study introduces Swift Lubrication for Industrial and Medical Equipment (SLIME), a rapid two‐step dip‐coating method that creates ultra‐low friction surfaces and robust anti‐fouling properties. SLIME demonstrates versatility across various applications, providing material‐independent coatings that enhance biocompatibility and performance without ...
Yeontaek Lee   +11 more
wiley   +1 more source

Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer.

open access: yesPLoS ONE, 2023
BackgroundSurgery is essential for curative treatment of solid tumors. Evidence from recent retrospective clinical analyses suggests that use of propofol-based total intravenous anesthesia during cancer resection surgery is associated with improved ...
Julia Dubowitz   +11 more
doaj   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

open access: yesAdvanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen   +10 more
wiley   +1 more source

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

open access: yesAdvanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin   +6 more
wiley   +1 more source

Anesthetic considerations during surgical intervention in Woake’s syndrome -a case report [PDF]

open access: yesKorean Journal of Anesthesiology, 2019
Background Woake’s syndrome (WS) is a recurrent nasal polyposis, accompanied by broadening of the nose, frontal sinus aplasia, dyscrinia, and bronchiectasis. There has been no previous report on anesthetic management in patients with WS. Case We describe
So Ron Choi   +4 more
doaj   +1 more source

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

open access: yesAdvanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie   +11 more
wiley   +1 more source

Anesthetic Management of a Child with Mitochondrial Neurogastrointestinal Encephalopathy

open access: yesCase Reports in Anesthesiology, 2015
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder associated with deficiency of thymidine phosphorylase (TP).
Vianey Q. Casarez   +3 more
doaj   +1 more source

Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus.

open access: yesPLoS ONE, 2012
The anesthetic excitement phase occurring during induction of anesthesia with volatile anesthetics is a well-known phenomenon in clinical practice. However, the physiological mechanisms underlying anesthetic-induced excitation are still unclear.
Klaus Becker   +6 more
doaj   +1 more source

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