Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish
Food Frontiers, EarlyView.In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia +14 more
wiley +1 more source
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties
The Journal of General Physiology, 2014 Volatile anesthetics act directly on neuronal sodium channels, independently of effects on the lipid bilayer.
K. Herold +6 more
semanticscholar +1 more source
Enhanced charge-independent Mitochondrial Free Ca\u3csup\u3e2+\u3c/sup\u3e and Attenuated ADP-induced NADH Oxidation by Isoflurane: Implications for Cardioprotection [PDF]
, 2012 Modulation of mitochondrial free Ca2 + ([Ca2 +]m) is implicated as one of the possible upstream factors that initiates anesthetic-mediated cardioprotection against ischemia–reperfusion (IR) injury.
Agarwal, Bhawana +4 more
core +1 more source
Food Safety and Health, EarlyView.This study shows the protective effects of potential probiotic strain of Pediococci strains against diarrheal Escherichia coli strains in Caenorhabditis elegans model system. The E. coli strains resulted in severe morphological and physiological damage to the worm whereas the probiotic interventions were able to reduce these damages.
Gunjan Sadera +4 more
wiley +1 more source
Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery [PDF]
, 2016 Background: The noble gas helium induces pre- and postconditioning in animals and humans. Volatile anesthetics induce cardioprotection in humans undergoing coronary artery bypass graft (CABG) surgery.
Brevoord, Daniel +9 more
core +7 more sources
Research progress on the depth of anesthesia monitoring based on the electroencephalogram
Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley +1 more source
Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence
Journal of Translational Medicine, 2018 Background The relationship between surgery and anesthetic-induced immunosuppression and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system (SNS) to cause ...
Ryungsa Kim
doaj +1 more source
, 2016 Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L +5 more
core +3 more sources
Use of the TIPS Technique as a Possible Method of Acute Inhalation Toxicity Assessment
Journal of Applied Toxicology, EarlyView.ABSTRACT Acute inhalation toxicity studies provide crucial information regarding short‐term exposure to volatile chemicals and help to ensure the safe handling and use of these chemicals. However, acute inhalation toxicity assessment requires specialized equipment, and most animal facilities are not able to carry out such studies.
Dina Mourad Saleh +8 more
wiley +1 more source
Effects of General Anesthetics on Excitatory and Inhibitory Synaptic Transmission in Area CA1 of the Rat Hippocamptls In Vitro [PDF]
, 1999 It is unclear whether general anesthetics induce enhancement of neural inhibition and/or attenuation of neural excitation.We studied the effects of pentobarbital (5xl0^mol/L), propofol (5x10^ mol/L), ketamine (10^ mol/L), halothane (1.5 vol%) and ...
Wakasugi Masahiro
core +1 more source