Results 181 to 190 of about 19,854 (293)

Transition From a High‐Sugar and Butter to a Standard Diet Leads to Cecal Dysbiosis, Disrupts Intestinal Homeostasis, and Favors Increased Ethanol Consumption and Preference

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
Male C57BL/6 mice were switched from a high‐sugar/high‐fat diet to a control diet with or without free‐choice 10% ethanol. The switch reshaped the cecal microbiota and metabolome (alpha diversity increased; polyamines and selected bile acids decreased) and reduced colonic barrier markers.
Renato Elias Moreira Júnior   +8 more
wiley   +1 more source

Management of malignant hyperthermia: diagnosis and treatment

open access: yesTherapeutics and Clinical Risk Management, 2014
Daniel Schneiderbanger, Stephan Johannsen, Norbert Roewer, Frank SchusterDepartment of Anaesthesia and Critical Care, University of Wuerzburg, Wuerzburg, GermanyAbstract: Malignant hyperthermia is a potentially lethal inherited disorder characterized by ...
Schneiderbanger D   +3 more
doaj  

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes. [PDF]

open access: yesClin Immunol, 2021
Yuki K   +4 more
europepmc   +1 more source

Do Volatile Anesthetics Act as Ideal Gases?

open access: bronze, 1979
E. I. Eger, Blair Johnson
openalex   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 10, Page 2056-2067, October 2025.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont   +4 more
wiley   +1 more source

Patterns and Processes of Genomic Evolution Inferred From the Ten Smallest Vertebrate Genomes

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
By integrating phylogenetic relationships derived from nuclear DNA with population genetic analyses across ten pufferfish species, the genetic differentiation mechanisms underpinning the radiative speciation of the most compact vertebrate genomes has elucidated.
Kaiqiang Liu   +22 more
wiley   +1 more source

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