Results 51 to 60 of about 2,759 (244)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Availability assessment of voltage source converter HVDC grids using optimal power flow-based remedial actions

open access: yesHigh Voltage, 2020
This study proposes a methodology for assessing the availability of voltage source converter high-voltage direct current (HVDC) grids based on the enumeration methodology of contingency analysis with N − 2 criteria and makes contributions in the ...
Mario A. Rios   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Transient stability analysis of virtual synchronous generator with current saturation by multiple Lyapunov functions method

open access: yesIET Generation, Transmission & Distribution
This paper demonstrates that the switching of one grid‐connected virtual synchronous generator (VSG) between two control modes, namely constant voltage control (CVC) and current limiting control (CLC) happens at the derived two switching lines.
Yujun Li   +4 more
doaj   +1 more source

Control of a synchronverter-based soft open point in a distribution network

open access: yesThe Journal of Engineering, 2019
The presence of distributed generation (DG) in a power distribution network can cause difficulties in managing the voltage, power flow and fault level as the network was designed for supplying passive loads. This study focuses on the control of a back-to-
Ruizhu Wu   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Evaluation of DC-link voltage ripple in five-phase PWM voltage source inverters

open access: yesThe Journal of Engineering, 2019
This paper presents the analysis of the DC-link voltage switching ripple in five-phase PWM voltage source inverters with balanced load. The analysis is particularly important for the design and selection of a DC-link capacitor making it possible to meet ...
M. Vujacic   +4 more
doaj   +1 more source

Preliminary design of a mobile lunar power supply [PDF]

open access: yes
A preliminary design for a Stirling isotope power system for use as a mobile lunar power supply is presented. Performance and mass of the components required for the system are estimated.
Fulmer, Christopher R.   +2 more
core   +1 more source

Infrared light emission from atomic point contacts [PDF]

open access: yes, 2016
Gold atomic point contacts are prototype systems to evidence ballistic electron transport. The typical dimension of the nanojunction being smaller than the electron-phonon interaction length, even at room temperature, electrons transfer their excess ...
Dumas, Ph.   +3 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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