MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J. +3 more
core
The molecular transition that confers voltage dependence to muscle contraction
What is the molecular origin of voltage dependence in skeletal muscle excitation-contraction? Cholinergic transmission to the muscle fiber triggers action potentials, which are sensed by voltage-gated L-type calcium channels (CaV1.1).
Marina Angelini +8 more
doaj +1 more source
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov +8 more
wiley +1 more source
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht +5 more
wiley +1 more source
Role of Voltage-Dependent Calcium Channel Long-Term Potentiation (LTP) and NMDA LTP in Spatial Memory [PDF]
Albert M. Borroni +3 more
openalex +1 more source
Achieving Large and Anisotropic Spin‐Mediated Thermal Transport in Textured Quantum Magnets
An advanced solvent‐cast cold pressing method is developed to synthesize highly textured quantum magnets. By aligning spin chains in Ca2CuO3 perpendicular to the pressing direction, a spin‐mediated thermal conductivity of 10 ± 1 W m⁻¹ K⁻¹ is achieved, the highest reported for polycrystalline quantum materials.
Shucheng Guo +6 more
wiley +1 more source
Caveolae-Specific CaMKII Signaling in the Regulation of Voltage-Dependent Calcium Channel and Cardiac Hypertrophy. [PDF]
Tanaka S, Fujio Y, Nakayama H.
europepmc +1 more source
Rocker Is a New Variant of the Voltage-Dependent Calcium Channel GeneCacna1a [PDF]
Theresa A. Zwingman +3 more
openalex +1 more source
Discovery of a Novel Non-Narcotic Analgesic Derived from the CL-20 Explosive: Synthesis, Pharmacology and Target Identification of Thio-wurtzine, a Potent Inhibitor of the Opioid Receptors and the Voltage-Dependent Calcium Channels [PDF]
Stephanie Aguero +9 more
openalex +1 more source

