Results 171 to 180 of about 101,918 (291)

The Conopeptide αD-FrXXA, an Inhibitor of Voltage-Gated Potassium Channels. [PDF]

Mar Drugs
Martínez-Hernández L, López-Vera E, Rodriguez-Ruiz XC, Ortíz-Arellano MA.   +3 more
europepmc   +1 more source

Allisartan ameliorates vascular remodeling through regulation of voltage-gated potassium channels in hypertensive rats. [PDF]

BMC Pharmacol Toxicol, 2021
Zhang X, Zhao Z, Xu C, Zhao F, Yan Z.
europepmc   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Targeting Voltage-Gated Potassium Channels in Breast Cancer: Mechanistic Insights into 4-Aminopyridine-Induced Cell Death. [PDF]

Int J Mol Sci
Cüce-Aydoğmuş EM, İyiol P, İnhan-Garip GA.   +2 more
europepmc   +1 more source

Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons. [PDF]

Mol Brain, 2021
Yang YS, Choi JH, Rah JC.
europepmc   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Inhibitory effect of sulfur dioxide inhalation on Hering-Breuer inflation reflex in mice: role of voltage-gated potassium channels.

J Appl Physiol (1985), 2023
Chan NJ, Hsu CC, Lin YS, Lin RL, Lee LY.
europepmc   +1 more source

Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior. [PDF]

PLoS One, 2021
Jerng HH, Patel JM, Khan TA, Arenkiel BR, Pfaffinger PJ.   +4 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Vasorelaxant effects of 3-methoxycatechol are not via direct activation of voltage-gated potassium channels. [PDF]

Vascul Pharmacol
Manville RW, Baldwin SN, Schaub OH, Jepps TA, Abbott GW.   +4 more
europepmc   +1 more source