Results 191 to 200 of about 100,024 (290)

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

Water, Protons, and the Gating of Voltage-Gated Potassium Channels. [PDF]

Membranes (Basel)
Kariev AM, Green ME.
europepmc   +1 more source

Celebrities in the heart, strangers in the pancreatic beta cell: Voltage-gated potassium channels K_v 7.1 and K_v 11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes. [PDF]

Acta Physiol (Oxf), 2022
Lubberding AF, Juhl CR, Skovhøj EZ, Kanters JK, Mandrup-Poulsen T, Torekov SS.   +5 more
europepmc   +1 more source

Functional large-conductance calcium and voltage-gated potassium channels in extracellular vesicles act as gatekeepers of structural and functional integrity. [PDF]

Nat Commun
Sanghvi S, Sridharan D, Evans P, Dougherty J, Szteyn K, Gabrilovich D, Dyta M, Weist J, Pierre SV, Gururaja Rao S, Halm DR, Chen T, Athanasopoulos PS, Dolga AM, Yu L, Khan M, Singh H.   +16 more
europepmc   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Carboxyl-group compounds activate voltage-gated potassium channels via a distinct mechanism. [PDF]

J Gen Physiol
Rönnelid O, Elinder F.
europepmc   +1 more source

Chemically‐Linked Heterostructures of Palladium Nanosheets and 2H‐MoS2

Small, EarlyView.
The photoresponse of MoS2 devices is extended to the near‐infrared region (up to 1700 nm) through chemical connection to Pd nanosheets (PdNS). A maleimide is used for covalent connection to MoS2, and a phenyl bromide moiety for linkage to the PdNS. In the absence of the chemical linker, van der Waals heterostructures show poorer enhancement of the ...
Ramiro Quirós‐Ovies, Pablo Bastante, Simon Hettler, Víctor Vega‐Mayoral, Sergio Aina, Vasileios Balos, Thomas Pucher, Andrés Castellanos‐Gomez, Raul Arenal, Juan Cabanillas‐Gonzalez, Emilio M. Pérez, Jesús Santamaría, Víctor Sebastian   +12 more
wiley   +1 more source

Kv3.1 Voltage-gated Potassium Channels Modulate Anxiety-like Behaviors in Female Mice. [PDF]

Neuroscience
Page CE, Coutellier L.
europepmc   +1 more source

Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels. [PDF]

Front Physiol, 2020
van der Horst J, Greenwood IA, Jepps TA.
europepmc   +1 more source