Results 221 to 230 of about 110,652 (333)

The propofol binding sites of prokaryotic voltage-gated sodium channels [PDF]

, 2020
Elaine Yang, Weiming Bu, Antonio Suma, Vincenzo Carnevale, Kimberly C. Grasty, Patrick J. Loll, Kellie A. Woll, Natarajan V. Bhanu, Benjamin A. García, Roderic G. Eckenhoff, Manuel Covarrubias   +10 more
openalex   +1 more source

Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential. [PDF]

Front Cell Neurosci, 2022
Bigsby S, Neapetung J, Campanucci VA.
europepmc   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels. [PDF]

Front Physiol, 2023
Pierre M, Djemai M, Chapotte-Baldacci CA, Pouliot V, Puymirat J, Boutjdir M, Chahine M.   +6 more
europepmc   +1 more source

Extracellular Protons Inhibit Charge Immobilization in the Cardiac Voltage-Gated Sodium Channel [PDF]

, 2013
D.K. Jones, Tom W. Claydon, Peter C. Ruben   +2 more
openalex   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Review of Physiology, Pathology, and Pharmacology of Voltage-Gated Sodium Channels in Regards to the Potential Role of NaV 1.8 Selective Inhibitor, Suzetrigine, for Chronic Pain Management. [PDF]

J Pain Res
Lam CM, Robinson CL, Aiyer R, Mata R, Xie K, Slitzky M, Latif H, Braun EB, Schatman ME, Gilligan C, Soin A, Latif U.   +11 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Venom Peptides Across Asian and American Tarantulas Utilize Dual Pharmacology to Target Activation and Fast Inactivation of Voltage-Gated Sodium Channels. [PDF]

Toxins (Basel)
Nashikwala AS, Kotapati C, Eagles DA, Lewis RJ, Cardoso FC.   +4 more
europepmc   +1 more source

Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels. [PDF]

J Neurosci, 2022
Liu H, Wang HG, Pitt G, Liu Z.
europepmc   +1 more source