Results 181 to 190 of about 1,906,569 (335)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel. [PDF]

Proc Natl Acad Sci U S A
Echeverría F, Peña-Pichicoi A, Fernandez M, Carrasquel-Ursulaez W, Castillo JP, Alvarez O, Latorre R.   +6 more
europepmc   +1 more source

Surface plasmon resonance (SPR)-based highly integrated optical fiber sensor for simultaneous detection of temperature, magnetic field, methane, relative humidity, voltage and hydrogen [PDF]

Chao Liu, Weiqiang Wang, Jingwei Lv, Famei Wang, Jianxin Wang, Wei Liu, Qiang Liu, Paul Kim-Ho Chu   +7 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reinvestigation of Absorption Spectroscopic Thermal Dynamics of Archaerhodopsin 3 Based Voltage Sensor QuasAr1. [PDF]

Bioengineering (Basel)
Penzkofer A, Silapetere A, Hegemann P.
europepmc   +1 more source

Voltage sensor movements of Ca_V1.1 during an action potential in skeletal muscle fibers. [PDF]

Proc Natl Acad Sci U S A, 2021
Banks Q, Bibollet H, Contreras M, Bennett DF, Bannister RA, Schneider MF, Hernández-Ochoa EO.   +6 more
europepmc   +1 more source

PIP2 tunes voltage sensor-targeted drug modulation of Kv7.2

Thomas M. Hammond, Shawn M. Lamothe, Harley T. Kurata   +2 more
openalex   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Design and Simulation Test of Non-Contact Voltage Sensor. [PDF]

Sensors (Basel)
Peng H, Liu H, Shang K, Li G, Zhao L.
europepmc   +1 more source

Design and Experiment of Anti-Particle-Contamination MEMS Thermal Flow Sensor by Channel Geometry Optimization and Voltage Regulation

Qilin Jiang, Jian Wu, Junming Hou, Zhenxiang Yi   +3 more
openalex   +1 more source