Results 11 to 20 of about 417,703 (296)

Voltage sensor inactivation in potassium channels [PDF]

Frontiers in Pharmacology, 2012
In voltage-gated potassium (Kv) channels membrane depolarization causes movement of a voltage sensor domain. This conformational change of the protein is transmitted to the pore domain and eventually leads to pore opening.
Robert eBähring, Jan eBarghaan, Regina eWestermeier, Jessica eWollberg   +3 more
doaj   +3 more sources

Optimized tight binding between the S1 segment and KCNE3 is required for the constitutively open nature of the KCNQ1-KCNE3 channel complex

eLife, 2022
Tetrameric voltage-gated K+ channels have four identical voltage sensor domains, and they regulate channel gating. KCNQ1 (Kv7.1) is a voltage-gated K+ channel, and its auxiliary subunit KCNE proteins dramatically regulate its gating.
Go Kasuya, Koichi Nakajo
doaj   +1 more source

Concept level evaluation of the optical voltage and current sensors and an arrayed waveguide grating for aero-electrical system applications [PDF]

, 2007
In this paper we present, for the first time, the hybrid fiber-optic voltage and current sensors interrogated using an arrayed waveguide grating (AWG) device.
Fusiek, G., McDonald, J.R., Niewczas, P.
core   +1 more source

Voltage Sensor Movements [PDF]

The Journal of General Physiology, 2002
The voltage dependence of K+, Na+, and Ca2+ channels is brought about by a voltage sensor that moves ∼12–13 e across the entire electric field ([Schoppa et al., 1992][1]; [Hirschberg et al., 1996][2]; [Noceti et al., 1996][3]).
openaire   +2 more sources

Advances in Engineering and Application of Optogenetic Indicators for Neuroscience

Applied Sciences, 2019
Our ability to investigate the brain is limited by available technologies that can record biological processes in vivo with suitable spatiotemporal resolution.
Kiryl D. Piatkevich, Mitchell H. Murdock, Fedor V. Subach   +2 more
doaj   +1 more source

Uncooperative Voltage Sensors [PDF]

Journal of General Physiology, 2009
A typical voltage-gated potassium (Kv) or sodium channel is exquisitely sensitive to small changes of membrane potential, so much so that a depolarization of
openaire   +2 more sources

Design and Simulation Test of an Open D-Dot Voltage Sensor

Sensors, 2015
Nowadays, sensor development focuses on miniaturization and non-contact measurement. According to the D-dot principle, a D-dot voltage sensor with a new structure was designed based on the differential D-dot sensor with a symmetrical structure, called an
Yunjie Bai, Jingang Wang, Gang Wei, Yongming Yang   +3 more
doaj   +1 more source

Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels [PDF]

, 2017
Large conductance Ca(2+)-activated K(+) channels (BK channels) gate open in response to both membrane voltage and intracellular Ca(2+). The channel is formed by a central pore-gate domain (PGD), which spans the membrane, plus transmembrane voltage ...
Adams, Adelman, Alvarez, Atkinson, Bao, Bao, Barrett, Behrens, Braun, Brayden, Brelidze, Brelidze, Budelli, Butler, Cox, Cui, Cui, Ferguson, Guohui Zhang, Hite, Hite, Horrigan, Horrigan, Hu, Hudspeth, Hudspeth, Jianmin Cui, Jingyi Shi, Karl L. Magleby, Kelli McFarland, Lancaster, Latorre, Lawrence Salkoff, Lee, Lee, Li, Lingle, Long, Marty, Meera, Meera, Meredith, Nimigean, Niu, Orio, Pallotta, Petersen, Robitaille, Rothberg, Schreiber, Shen, Shi, Silberberg, Sun, Sweet, Tao, Tseng-Crank, Wallner, Wei, Wellman, Wu, Wu, Xia, Xia, Xia, Yakang Jin, Yang, Yang, Yang, Yang, Yanyan Geng, Yuan, Yuan, Zhang, Zhang   +74 more
core   +3 more sources

A Voltage-Sensor Water Pore [PDF]

Biophysical Journal, 2006
Voltage-sensor (VS) domains cause the pore of voltage-gated ion channels to open and close in response to changes in transmembrane potential. Recent experimental studies suggest that VS domains are independent structural units. This independence is revealed dramatically by a voltage-dependent proton-selective channel (Hv), which has a sequence ...
Freites, J Alfredo, Tobias, Douglas J, White, Stephen H   +2 more
openaire   +3 more sources

The Identification of Travelling Waves in a Voltage Sensor Signal in a Medium Voltage Grid Using the Short-Time Matrix Pencil Method

Energies, 2022
Most of the fault wave localization methods are based on the analysis of line current transformed by current transformers and are limited to high voltage grids. Fault wave localization in medium voltage grids is still being developed. This paper presents
Piotr Łukaszewski, Łukasz Nogal, Artur Łukaszewski   +2 more
doaj   +1 more source