Results 91 to 100 of about 2,462,591 (297)

Spacial and temporal dynamics of the volume fraction of the colloidal particles inside a drying sessile drop

, 2010
Using lubrication theory, drying processes of sessile colloidal droplets on a solid substrate are studied. A simple model is proposed to describe temporal dynamics both the shape of the drop and the volume fraction of the colloidal particles inside the ...
A Sole, AJ Petsi, AV Kistovich, BJ Fischer, C Koch, C Koch, CC Annarelli, D Brutin, DM Anderson, E Rapis, E Widjaja, F Parisse, H Hu, HS Kim, Irina V. Vodolazskaya, IV Vodolazskaya, JP Burelbach, K Monkos, K Monkos, K Ozawa, L Pauchard, L Reyes, LV Savina, Olga P. Isakova, P Takhistov, R Bhardwaj, R Zheng, RD Deegan, RV Craster, T Okuzono, T Okuzono, T Yakhno, TA Witten, TA Yakhno, TA Yakhno, V Ragoonanan, VN Shabalin, VV Lychagov, Y Jung, YD Chashechkin, YO Popov, Yuri Yu. Tarasevich, YY Tarasevich, YY Tarasevich, YY Tarasevich, YY Tarasevich   +45 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Simulation of Cuttings Settling in Horizontal Shale Gas Wells

Shiyou jixie, 2021
In current researches on cuttings migration, the common practice is to extract the cuttings volume fraction, cuttings velocity and cuttings bed thickness from a certain position in the annulus.
Chen Kun, Xia Chengyu, Feng Chao, Fang Yong, Wang Xudong, Wu Jiwei   +5 more
doaj  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Forced motion of a probe particle near the colloidal glass transition

, 2004
We use confocal microscopy to study the motion of a magnetic bead in a dense colloidal suspension, near the colloidal glass transition volume fraction $\phi_g$.
A. C Levitt, Angel C. A., Angell C. A., Courtland R. E., D Schaar, Dinsmore A. D., E. R Weeks, P Habdas, Schweizer K. S., Stillinger F. H.   +9 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Anisotropic AGN Outflows and Enrichment of the Intergalactic Medium

, 2009
We investigate the cosmological-scale influence of outflows driven by AGNs on metal enrichment of the intergalactic medium. AGNs are located in dense cosmological structures which tend to be anisotropic.
Barai, Barai, Barger, Begelman, Bicknell, Blundell, Chartas, Chartas, Choi, Ciotti, Ciotti, Crenshaw, Croston, Das, Dasgupta, Fragile, Furlanetto, Ganguly, Gebhardt, Granato, Grenon, Hickox, Hinshaw, Ho, Ho, Hopkins, Hugo Martel, Joël Germain, Juneau, King, Kormendy, Kronberg, Krongold, Laor, Levine, Mac Low, Magorrian, Marconi, Martel, Martel, Martel, Miller, Murray, Nesvadba, O'Brien, Paramita Barai, Peterson, Pieri, Rafter, Recchi, Rees, Reichard, Richards, Scannapieco, Scannapieco, Schlesinger, Shang, Shankar, Shen, Silk, Springel, Thacker, van Breugel, Wyithe, Yu   +64 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The optimal fiber volume fraction and fiber-matrix property compatibility in fiber reinforced composites [PDF]

Although the question of minimum or critical fiber volume fraction beyond which a composite can then be strengthened due to addition of fibers has been dealt with by several investigators for both continuous and short fiber composites, a study of maximum
Pan, Ning
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source