Results 111 to 120 of about 979,356 (312)
Low-volume-fraction limit for polymer fluids
Journal of Mathematical Analysis and Applications, 2011 We study a stationary, purely viscous polymer flow through a porous medium modelled as a periodic array of cells consisted of a fluid part and a solid one. Solid parts of the domain present impermeable obstacles, whose impact on fluid flow may be seen as a slowing factor through averaged quantities such as the permeability function, obtained by the ...
Fratrović, Tomislav +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Step-driven ventilatory volume, as a fraction of concurrent volume, during inspiration and expiration. [PDF]
, 2013 Step-driven ventilatory volume, as a fraction of concurrent volume, during inspiration and expiration.
Dennis M. Bramble (444386) +2 more
core +1 more source
Nonuniversality in Low-Volume-Fraction Ostwald Ripening
Journal of Statistical Physics, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Conti, S +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Power law approximations to gas volume fraction and velocity profiles in low void fraction vertical gas-liquid flows [PDF]
, 2004 A dual sensor conductance probe was used to measure the distributions of the local gas volume fraction and the local gas axial velocity in vertical upward, bubby air–water flows in which the mean gas volume fraction was less than 0.1.
Panayotopoulos, Nikolaos +5 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Two-phase flow meter for determining water and solids volumetric flow rate in vertical and inclined solids-in-water flows [PDF]
Multiphase flow can be defined as the simultaneous flow of a stream of two or more phases. Solids-in-water flow is a multiphase flows where solids and liquid are both present. Due to the density differences of the two phases, the results for such flow is
Muhamedsalih, Yousif
core
End-systolic Pressure–Volume Relation, Ejection Fraction, and Heart Failure: Theoretical Aspect and Clinical Applications [PDF]
, 2015 A mathematical formalism describing the nonlinear end-systolic pressure–volume relation (ESPVR) is used to derive new indexes that can be used to assess the performance of the heart left ventricle by using the areas under the ESPVR (units of energy), the
Rachad M. Shoucri
core +1 more source