Results 101 to 110 of about 979,356 (312)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Flow regime identification and volume fraction prediction in multiphase flows by means of gamma-ray attenuation and artificial neural networks [PDF]

open access: yes, 2010
This work presents a new methodology for flow regimes identification and volume fraction predictions in wateregaseoil multiphase systems. The approach is based on gamma-ray pulse height distributions (PHDs) pattern recognition by means the artificial ...
SALGADO, César Marques   +3 more
core  

SPATIAL STATISTICS FOR SIMULATED PACKINGS OF SPHERES

open access: yesImage Analysis and Stereology, 2011
This paper reports on spatial-statistical analyses for simulated random packings of spheres with random diameters. The simulation methods are the force-biased algorithm and the Jodrey-Tory sedimentation algorithm.
Alexander Bezrukov   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Measurement of Reference Bubble Velocity Vector for a Local 4 Sensor Probe Using Orthogonal High Speed Cameras [PDF]

open access: yes, 2007
In recent years, there has been an increase in the level of interest shown in making flow rate measurements in multiphase flow. This in part has been brought about by the metering requirements of the oil and natural gas industries.
Lucas, Gary, Pradhan, Suman, Zhao, X.
core  

Estimation Model for Effective Thermal Conductivity of Reinforced Concrete Containing Multiple Round Rebars

open access: yesInternational Journal of Concrete Structures and Materials, 2018
The objective of this research is to estimate the effective thermal conductivity model for the reinforced concrete containing round rebars. The thermal network concept and Fourier’s law are used to develop a mathematical model to calculate the effective ...
Hyung Gyun Noh   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Local Volume Fraction Fluctuations in Random Media [PDF]

open access: yes, 2007
Although the volume fraction is a constant for a statistically homogeneous random medium, on a spatially local level it fluctuates. We study the full distribution of volume fraction within an observation window of finite size for models of random media ...
Quintanilla And   +2 more
core  

An optical method for measuring the near-wall volume fraction in granular dispersions [PDF]

open access: yes, 2016
The volume fraction plays a crucial role in the dynamics of granular flows. This work is devoted to developing a novel cost-effective optical method for determining the near-wall volume fraction.
SARNO, Luca   +3 more
core   +1 more source

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