Results 101 to 110 of about 2,180,608 (342)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Free Surface Characteristics of Flow around Two Side-by-Side Circular Cylinders
Journal of Marine Science and Engineering, 2018 The three-dimensional free surface characteristics of flow around two equal diameter cylinders in a side-by-side arrangement were studied numerically. The flow fields were simulated with a three-dimensional finite volume method based on the RNG k-ɛ model
Dengsong Li +3 more
doaj +1 more source
, 1970 Tool, consisting of a graduated storage vessel and a control panel, can determine the amount of gas entrained by fluid in a closed system, the amount of fluid remaining in a dried system of known volume, or the volume of a container of unknown ...
Erbe, C. J., Poulos, L. J.
core +1 more source
, 2007 We consider a hyperbolic system of three conservation laws in one space variable. The system is a model for fluid flow allowing phase transitions; in this case the state variables are the specific volume, the velocity and the mass density fraction of the
Amadori, Debora, Corli, Andrea
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
SIMULATIONS OF THE WATER FREEZING PROCESS – NUMERICAL BENCHMARKS
TASK Quarterly, 2003 Three numerical benchmarks concerning the freezing of water in small enclosures are analysed using the commercial FLUENT code. The first case is a steady-state natural convection in a differentially heated cavity for temperatures near the freezing point.
TOMASZ MICHAŁEK, TOMASZ A. KOWALEWSKI
doaj
Computational and Mathematical BiophysicsThree-phase fluid-structure interaction (FSI) problems couple the motion of solid structures and two different fluids, often exhibiting complex dynamics and posing challenges for computational investigation. The main objective of this paper is to present
Murshed Mohammad, Wang Jin
doaj +1 more source
Physically consistent simulation of transport of inertial particles in porous media [PDF]
, 2011 A new numerical approach is presented for simulating the movement of test particles suspended in an incompressible fluid flowing through a porous matrix.
Geurts, Bernard J. +3 more
core +1 more source
Loose packings of frictional spheres
, 2010 We have produced loose packings of cohesionless, frictional spheres by sequential deposition of highly-spherical, monodisperse particles through a fluid. By varying the properties of the fluid and the particles, we have identified the Stokes number (St) -
Attard +27 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source