Results 71 to 80 of about 2,180,608 (342)

A coupled finite-volume CFD solver for two-dimensional elasto-hydrodynamic lubrication problems with particular application to rolling element bearings [PDF]

, 2016
This paper describes a new computational fluid dynamics methodology for modelling elastohydrodynamic contacts. A finite-volume technique is implemented in the ‘OpenFOAM’ package to solve the Navier-Stokes equations and resolve all gradients in a ...
Dini, D, Hajishafiee, A, Ioannides, E, Kadiric, A   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review

Critical Care, 2012
Intravenous fluids are widely administered to maintain renal perfusion and prevent acute kidney injury (AKI). However, fluid overload is of concern during AKI. Using the Pubmed database (up to October 2011) we identified all randomised controlled studies
J. Prowle, H. Chua, S. Bagshaw, R. Bellomo   +3 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A Coupled Artificial Compressibility Method for Free Surface Flows

Journal of Marine Science and Engineering, 2020
Modeling free surface flows in a CFD context typically requires an incompressible approach along with a formulation to account for the air–water interface.
Dimitris Ntouras, George Papadakis
doaj   +1 more source

Vortex sheets and diffeomorphism groupoids

, 2018
In 1966 V.Arnold suggested a group-theoretic approach to ideal hydrodynamics in which the motion of an inviscid incompressible fluid is described as the geodesic flow of the right-invariant $L^2$-metric on the group of volume-preserving diffeomorphisms ...
Izosimov, Anton, Khesin, Boris
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Determination of extracellular fluid volume in healthy and azotemic cats [PDF]

, 2015
BACKGROUND: Methods for determining extracellular fluid volume (ECFV) are important clinically for cats. Bromide dilution has been studied in cats to estimate ECFV. Markers of GFR also distribute in ECFV and can be used for its measurement.
Back, Bird, Bird, Bland, Cousins, DiBartola, Elliott, Elliott, Elliott, Essig, Finch, Gleadhill, Heiene, Mutzel, Olsson, Peters, Peters, Peters, Pierson, Price, Sapirstein, Schoeller, Shemin, Vasavada, Vaughan, Watson, Zdolsek   +26 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Solar heat driven water circulation and aeration system for aquaculture [PDF]

, 2017
The proposed design concept of water aeration and updraft circulation in aquaculture is based on the Organic Rankine Cycle (ORC) technology and uses a solar energy absorbed by a floating collector.
Gusev, Sergei, van den Broek, Martijn, Ziviani, Davide   +2 more
core   +1 more source