Results 71 to 80 of about 1,475,677 (295)

Generation and Dynamics of Janus Droplets in Shear-Thinning Fluid Flow in a Double Y-Type Microchannel

open access: yesMicromachines, 2021
Droplets composed of two different materials, or Janus droplets, have diverse applications, including microfluidic digital laboratory systems, DNA chips, and self-assembly systems.
Fan Bai   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Stable cell-centered finite volume discretization for Biot equations [PDF]

open access: yes, 2015
In this paper we discuss a new discretization for the Biot equations. The discretization treats the coupled system of deformation and flow directly, as opposed to combining discretizations for the two separate sub-problems. The coupled discretization has
Nordbotten, Jan Martin
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Numerical Investigation of Cylindrical Water Droplets Subjected to Air Shock Loading at a High Weber Number

open access: yesFluids
This work is devoted to the computational investigation of the deformation and breakup of cylindrical water bodies in the high-speed airflow behind incident shock waves.
F. Edoardo Taglialatela   +1 more
doaj   +1 more source

A dilating vortex particle method for compressible flow [PDF]

open access: yes, 2002
Vortex methods have become useful tools for the computation of incompressible fluid flow. In this work, a vortex particle method for the simulation of unsteady two-dimensional compressible flow is developed.
Colonius, Tim   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

SIMPLIFIED VOLUME OF FLUID METHOD (SVOF) FOR TWO-PHASE FLOWS

open access: yesTASK Quarterly, 2008
The PLIC approach has been usually used in recent implementations of the VOF method i.e. the interphasal surface is approximated by a plane with an arbitrary orientation with respect to the computational cell.
MACIEJ MAREK   +2 more
doaj  

Inertial Coupling Method for particles in an incompressible fluctuating fluid [PDF]

open access: yes, 2015
We develop an inertial coupling method for modeling the dynamics of point-like 'blob' particles immersed in an incompressible fluid, generalizing previous work for compressible fluids.
Delgado-Buscalioni, R.   +3 more
core   +1 more source

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