Results 81 to 90 of about 1,475,070 (295)

Temperature induced pore fluid pressurization in geomaterials [PDF]

open access: yes, 2010
The theoretical basis of the thermal response of the fluid-saturated porous materials in undrained condition is presented. It has been demonstrated that the thermal pressurization phenomenon is controlled by the discrepancy between the thermal expansion ...
Ghabezloo, Siavash, Sulem, Jean
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Numerical Simulation of Wave Interaction with Oscillating Water Column in One Dimension

open access: yesنشریه مهندسی دریا, 2015
Oscillating water column (OWC) is one of the wave energy converting devices available. In this article, a numerical model has been introduced to simulate wave interaction with OWC in one dimensional plane.
seyed Hamidreza Sahebalzamani   +1 more
doaj  

Experimental Validation of Volume of Fluid Method for a Sluice Gate Flow

open access: yesAdvances in Mechanical Engineering, 2012
Laboratory experiments are conducted for 2D turbulent free surface flow which interacts with a vertical sluice gate. The velocity field, on the centerline of the channel flow upstream of the gate is measured using the particle image velocimetry technique.
A. A. Oner   +3 more
doaj   +1 more source

A Volume-of-Fluid based simulation method for wave impact problems [PDF]

open access: yesJournal of Computational Physics, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kleefsman, K.M.T.   +4 more
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Development of a phase change model for volume-of-fluid method in OpenFOAM [PDF]

open access: yesJournal of Heat and Mass Transfer Research, 2016
In this present study, volume of fluid method in OpenFOAM open source CFD package will be extended to consider phase change phenomena with modified model due to condensation and boiling processes.
Mohammad Bahreini   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Lattice Boltzmann Model for The Volume-Averaged Navier-Stokes Equations

open access: yes, 2014
A numerical method, based on the discrete lattice Boltzmann equation, is presented for solving the volume-averaged Navier-Stokes equations. With a modified equilibrium distribution and an additional forcing term, the volume-averaged Navier-Stokes ...
Ouyang, Jie   +2 more
core   +1 more source

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