Results 221 to 230 of about 3,219 (249)

Toxicology of deoxynivalenol (vomitoxin).

Journal of Toxicology and Environmental Health, Part A, 1996
Trichothecene mycotoxins are a group of structurally similar fungal metabolites that are capable of producing a wide range of toxic effects. Deoxynivalenol (DON, vomitoxin), a trichothecene, is prevalent worldwide in crops used for food and feed ...
B. Rotter, D. Prelusky, J. Pestka
semanticscholar   +1 more source

Natural occurrence of vomitoxin in Austrian and Canadian corn

European Journal of Applied Microbiology and Biotechnology, 1979
The trichothecene, vomitoxin, was found in two Austrian corn samples at levels of 1.3 and 7.9 ppm and in one Canadian corn sample at a level of 7.9 ppm; all three corn samples were rejected when fed to swine. Feed made from the latter corn sample contained 1.4 ppm vomitoxin. Kernels from these corn samples were examined for Fusarium graminearum.
A. Ciegler, R. F. Vesonder
openaire   +2 more sources

Vomitoxin (4-deoxynivalenol): effects on reproduction of mice and rats

Toxicology and Applied Pharmacology, 1984
Weanling male and female mice (F0) were fed daily diets containing 4-deoxynivalenol (DON) at concentrations that resulted in a dose of 0 or 2.0 mg/kg body wt in Experiment I and 0, 0.375, 0.75, or 1.5 mg/kg body wt in Experiment II. The test diets were continuously fed to the F0 parents and their progeny for the entire duration of these two experiments,
K.S. Khera, G. Angers, Carole Whalen, P.M. Scott, D.L. Arnold   +4 more
openaire   +3 more sources

Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course.

Toxicology and Applied Pharmacology, 1997
Acute oral exposure of B6C3F1 mice to vomitoxin (VT) has been previously shown to induce expression of mRNAs for cytokines that are characteristically produced in lymphoid tissues by macrophage and T cells.
Hui-Ren Zhou, Ding Yan, J. Pestka
semanticscholar   +1 more source

Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol).

Journal of Toxicology and Environmental Health, Part A, 1999
A single oral exposure to the trichothecene vomitoxin (VT) has been previously shown in the mouse to increase splenic mRNA levels for several cytokines in as little as 2 h.
H. R. Zhou, J. Harkema, D. Yan, J. Pestka   +3 more
semanticscholar   +1 more source

Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin

Food and Chemical Toxicology, 1989
The effect of dietary exposure to vomitoxin on serum immunoglobulin A (IgA) was evaluated in the B6C3F1 mouse. Levels of serum IgA were elevated maximally in mice fed 25 ppm vomitoxin in comparison with levels in mice fed 2, 10 or 50 ppm vomitoxin. Significant increases were detectable after as few as 4 wk in mice fed 25 ppm vomitoxin, and IgA levels ...
M.A. Moorman, R.L. Warner, James J. Pestka   +2 more
openaire   +2 more sources

Vomitoxin in diets for rainbow trout (Salmo gairdneri)

Aquaculture, 1983
Abstract The present study was conducted to obtain information as to the response and sensitivity of rainbow trout ( Salmo gairdneri ) to diets containing vomitoxin-contaminated corn. Feed refusal occurred when diets contained 20 μ g/g vomitoxin or more, but the trout recovered rapidly when subsequently fed a diet containing no detectable toxin ...
A.K. Lun, L.G. Young, Bill Woodward
openaire   +2 more sources

Occurrence of deoxynivalenol (vomitoxin) in beer in Turkey detected by HPLC

Food Control, 2007
Abstract The objective of this study was to investigate the deoxynivalenol (DON) contamination/level in beer consumed Turkey using high performance liquid chromatography (HPLC) with UV–visible detector at 220 nm. An acetonitrile–water (21 + 4, v/v) extract of samples first was cleaned up on a column packed with alumina–celite–charcoal (0.50 g + 0.25 ...
Diren Beyoğlu, Gülden Z. Omurtag
openaire   +2 more sources

Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition.

Toxicology and Applied Pharmacology, 1995
The effects of oral exposure to 0, 5, and 25 mg/kg body wt vomitoxin (VT) on cytokine mRNA levels in spleen, Peyer's patches (PP), liver, kidney, and small intestine were evaluated in B6C3F1 mice at 2 and 4 hr postexposure using RT-PCR in conjunction ...
J. Azcona-Olivera, Y. Ouyang, J. Murtha, F. Chu, J. Pestka   +4 more
semanticscholar   +1 more source

Feeding trials with vomitoxin (deoxynivalenol)-contaminated wheat: effects on swine, poultry, and dairy cattle.

Journal of the American Veterinary Medical Association, 1984
Nutritional and toxicologic feeding trials with 3 species of farm animals demonstrated that decreased feed consumption and reduced weight gains in pigs are the main effects of ingestion of a diet with low vomitoxin (deoxynivalenol; DON) content, eg, 2 mg
H. Trenholm, Hamilton Rm, D. W. Friend, Thompson Bk, K. Hartin   +4 more
semanticscholar   +1 more source