Results 231 to 240 of about 3,219 (249)
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Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats
Food and Chemical Toxicology, 2006Deoxynivalenol (DON, vomitoxin), is one of the most common contaminants of cereal grains world-wide. The effects of DON on fetal development were assessed in Charles River Sprague-Dawley rats. Pregnant female rats were gavaged once daily with DON at doses of 0, 0.5, 1, 2.5, or 5 mg/kg body weight on gestation days (GD) 6-19.
Nicholas Olejnik +7 more
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Food Additives and Contaminants, 1984
In order to assess human intake of deoxynivalenol (DON, vomitoxin) from wheat sources for regulatory purposes, the effects of food processing on DON retention and distribution must be known.
P. Scott +4 more
semanticscholar +1 more source
In order to assess human intake of deoxynivalenol (DON, vomitoxin) from wheat sources for regulatory purposes, the effects of food processing on DON retention and distribution must be known.
P. Scott +4 more
semanticscholar +1 more source
Immunoglobulin a Nephropathy as a Manifestation of Vomitoxin (Deoxynivalenol) Immunotoxicity
1990The trichothecenes, mycotoxins produced by members of the genus Fusarium, are of immense concern because of their frequent presence in agricultural staples such as wheat, corn, barley and oats.19,30,42 These compounds are sesquiterpenoids that are characterized by a trichothecane nucleus and that include some of the most potent inhibitors of protein ...
J-H. Tai +5 more
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Microbially detoxified vomitoxin-contaminated corn for young pigs
Journal of Animal Science, 1993A performance trial was conducted to evaluate the effect of microbially detoxified moldy corn in a corn-soybean meal-based starter diet for young pigs. Moldy corn containing 450 ppm of vomitoxin replaced clean corn in a control diet to give a diet containing 5 ppm of vomitoxin. The same amount of moldy corn was microbially detoxified by incubation with
L. G. Young, Ping He, C. Forsberg
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The toxicity of orally administered deoxynivalenol (vomitoxin) in rats and mice
Food and Chemical Toxicology, 1986Two studies were conducted with weanling male rodents in an attempt to ascertain more precisely the toxic effects of deoxynivalenol (DON). In a feeding study of approximately 18-wk duration, groups of 90 Swiss-Webster derived mice and 50 Sprague-Dawley rats were fed a commercial chow (118 ppb DON), and groups of 80 mice and 50 rats were fed either an ...
E.A. Nera +7 more
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Effects of deoxynivalenol (vomitoxin) on the humoral and cellular immunity of mice
Toxicology Letters, 1986Sublethal doses (0.00, 0.25, 0.50 and 1.00 mg/kg b.w./day) of vomitoxin (deoxynivalenol; DON) were studied for their effects on humoral and cellular immunity and serum proteins of inbred, male Swiss Webster mice in a series of 4 separate experiments. Vomitoxin was added to basal diet (less than the detection limit, i.e., less than 0.05 micrograms of ...
E.A. Nera +7 more
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Effects of Dihydrotestosterone and Estradiol on Experimental IgA Nephropathy Induced by Vomitoxin
Fundamental and Applied Toxicology, 1995Ingestion of the trichothecene vomitoxin (VT) by mice induces effects that mimic the common human glomerulonephritis, IgA nephropathy (IgAN). These include elevation of serum IgA, IgA immune complexes, and mesangial IgA deposition. Based on previous observations that male mice are more prone to VT-induced IgAN, the effects of castration of male and ...
James J. Pestka +3 more
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Preliminary study of the pharmacokinetics and toxicopathy of deoxynivalenol (vomitoxin) in swine
American Journal of Veterinary Research, 1985SUMMARY Study was made of the pharmacokinetics and toxicopathy of deoxynivalenol (don, vomitoxin) given iv to swine. In the 24 hours after swine were given don, clinical signs of vomiting, diarrhea, muscular weakness, tremors, and twilight coma were similar to those observed with other 12, 13-epoxytrichothecenes.
R W, Coppock +6 more
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