Disorders of Iron Metabolism: A “Sharp Edge” of Deoxynivalenol-Induced Hepatotoxicity [PDF]
Background/Objectives: Deoxynivalenol (DON), known as vomitoxin, is one of the most common mycotoxins produced by Fusarium graminearum, with high detection rates in feed worldwide.
Haoyue Guan+5 more
doaj +2 more sources
EVALUATION OF DIFFERENT SOURCES OF DEOXYNIVALENOL (VOMITOXIN) FED TO SWINE
Fifty-four barrows (27.5 ± 0.5 kg) were given ad libitum for 7 wk one of 18 diets prepared from field corn inoculated with different strains of Fusarium graminearum, naturally contaminated corn and wheat, pure deoxynivalenol (DON), and clean corn. The effect of 4.7 mg pure DON kg−1 feed was not significantly different from that of the control, whereas
Brian C. Foster+4 more
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Monoclonal-Antibody-Based Immunoassays for the Mycotoxins NX-2 and NX-3 in Wheat [PDF]
The fungal infestation of crops can cause major economic losses. Toxins produced by the causative fungi (mycotoxins) represent a potential safety hazard to people and livestock consuming them.
Chris M. Maragos+2 more
doaj +2 more sources
Effect of Feeding Deoxynivalenol (Vomitoxin)-Contaminated Barley to Horses
12,13-epoxytrichothec-9-en-8-one) is a naturally occurring trichothecene toxin produced by several Fusarium fungi that parasitize numerous cereal grains. Numerous species of Fusarium have been found to produce DON. The genus Fusarium occurs throughout the world and may affect corn, wheat, barley, oats, rice, and sorghum and complete feed formulations ...
Philip J. Johnson+2 more
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Chemical deoxygenation of the epoxide moiety in deoxynivalenol (vomitoxin) [PDF]
Reaction of triacetoxydeoxynivalenol (3) with hydrobromic acid–acetic acid at reflux temperatures yielded 3α,7α, 13,15-tetraacetoxy-2-bromo apotrichothec-9-en-8-one (5) and 3α,7α,15-triacetoxy-13-bromo-12-hydroxytrichothec-9-en-8-one (4). Dehalohydrination of the 13,12-bromohydrin derivative with Zn–acetic acid followed by deacetylation with sodium ...
Russell R. King, R. Greenhalgh
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Role of Glucagon-Like Peptide-1 and Gastric Inhibitory Peptide in Anorexia Induction Following Oral Exposure to the Trichothecene Mycotoxin Deoxynivalenol (Vomitoxin) [PDF]
Hui Jia+5 more
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Deoxynivalenol (Vomitoxin)-Induced Cholecystokinin and Glucagon-Like Peptide-1 Release in the STC-1 Enteroendocrine Cell Model Is Mediated by Calcium-Sensing Receptor and Transient Receptor Potential Ankyrin-1 Channel [PDF]
Food refusal is a hallmark of exposure of experimental animals to the trichothecene mycotoxin deoxynivalenol (DON), a common foodborne contaminant. Although studies in the mouse suggest that DON suppresses food intake by aberrantly inducing the release ...
Hui-Ren Zhou, James J. Pestka
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Pyrolytic Conversion of Vomitoxin-Contaminated Corn into Value-Added Products [PDF]
Deoxynivalenol (DON) (also called vomitoxin) is a mycotoxin caused by pathogens that periodically contaminate crops such as maize, wheat, barley, oats, and rye, making them unusable. We explored pyrolysis as a process for the decontamination of vomitoxin-
Shokooh Karami+3 more
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Baseline tebuconazole sensitivity and potential resistant risk in Fusarium graminearum [PDF]
Background The Fusarium head blight caused by Fusarium graminearum results in reduced crop yields and the potential for vomitoxin contamination, which poses a risk to both human and livestock health.
Feng Zhou+7 more
doaj +2 more sources
Anorexia Induction by the Trichothecene Deoxynivalenol (Vomitoxin) Is Mediated by the Release of the Gut Satiety Hormone Peptide YY [PDF]
Consumption of deoxynivalenol (DON), a trichothecene mycotoxin known to commonly contaminate grain-based foods, suppresses growth of experimental animals, thus raising concerns over its potential to adversely affect young children.
Brenna M. Flannery+2 more
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