Trichothecene mycotoxins are sesquiterpenoid compounds primarily produced by fungi in taxonomical genera such as Fusarium, Myrothecium, Stachybotrys, Trichothecium, and others, under specific climatic conditions on a worldwide basis.
Magdalena Polak-Śliwińska+1 more
doaj +1 more source
Assessment of the feed additive consisting of Saccharomyces cerevisiaeMUCL 39885 (Biosprint®) for cattle for fattening for the renewal of its authorisation (Prosol SPA). [PDF]
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of Saccharomyces cerevisiae MUCL 39885 (Biosprint®) as a feed additive for cattle for fattening (category: zootechnical; functional group: gut flora stabiliser).
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)+19 more
europepmc +2 more sources
Abstract Fusarium head blight (FHB) remains one of the most destructive diseases in wheat. Primarily caused by the mycotoxigenic fungi Fusarium graminearum, FHB results in both widespread yield loss and deoxynivalenol (DON) contamination of wheat grain.
Junzhe Wu+4 more
wiley +1 more source
Deoxynivalenol Biomarkers in the Urine of UK Vegetarians
Deoxynivalenol (DON) is produced by Fusarium graminearum and is one of the most commonly occurring trichothecenes. Vegetarians are alleged to be a high-risk group for DON exposure due to high intakes of cereals susceptible to the growth of the mycotoxin.
Liz Wells+14 more
doaj +1 more source
Deoxynivalenol modulated mucin expression and proinflammatory cytokine production, affecting susceptibility to enteroinvasive Escherichia coli infection in intestinal epithelial cells. [PDF]
Abstract Deoxynivalenol (DON) is a common mycotoxin in crops that could induce intestinal inflammation, affecting the susceptibility of intestinal epithelial cells (IECs) to pathogen infection. This study aimed to investigate DON's effects on mucin and cytokine production as part of the local immune system and how it affected intestinal susceptibility ...
Wan MLY+4 more
europepmc +2 more sources
Abstract Fusarium head blight (FHB) is an economically and environmentally concerning disease of wheat (Triticum aestivum L). A two‐pronged approach of marker‐assisted selection coupled with genomic selection has been suggested when breeding for FHB resistance. A historical dataset comprised of entries in the Southern Uniform Winter Wheat Scab Nursery (
Zachary J. Winn+4 more
wiley +1 more source
Pyroptosis-Mediated Damage Mechanism by Deoxynivalenol in Porcine Small Intestinal Epithelial Cells
Deoxynivalenol (DON) is known as a vomitoxin, which frequently contaminates feedstuffs, such as corn, wheat, and barley. Intake of DON-contaminated feed has been known to cause undesirable effects, including diarrhea, emesis, reduced feed intake ...
Tae Hong Kang+4 more
doaj +1 more source
Trichothecenes NIV and DON modulate the maturation of murinedendritic cells [PDF]
Nivalenol (NIV) and Deoxynivalenol (DON), mycotoxins of the trichothecene family are considered very common food contaminants. In this work, we investigated whether the immunotoxic effects ascribed to these trichothecenes may be mediated by perturbations
Bergamo P.+4 more
core +1 more source
Mycotoxins nivalenol and deoxynivalenol differently modulate cytokine mRNA expression in Jurkat T cells. [PDF]
Deoxynivalenol (DON) and its hydroxylated form nivalenol (NIV) are Fusarium mycotoxins that occur in cereal grains alone or in combination. Several studies have shown that these metabolites affect lymphocyte functions.
BERGAMO P+4 more
core +1 more source
Mutagenic effects of selected trichothecene mycotoxins and their combinations with aflatoxin B1
The authors focused on the amplification of data on the mutagenicity of selected trichothecene mycotoxins (T-2 toxin, vomitoxin) and their combination with aflatoxin B1,which is known to be a strong mutagen.
P. Šmerák+4 more
doaj +1 more source