Results 111 to 120 of about 160,288 (338)
Sex-dependent influence of endogenous estrogen in pulmonary hypertension [PDF]
Rationale: The incidence of pulmonary arterial hypertension (PAH) is greater in women suggesting estrogens may play a role in the disease pathogenesis. Experimentally, in males exogenously administered estrogen can protect against PH; however in models ...
Audrey F. Wright+17 more
core +1 more source
COMBINATION OF THE ULCERATIVE COLITIS AND VON WILLEBRAND DISEASE (A CASE REPORT)
In the article the clinical observation of a rare combination of ulcerative colitis with von Willebrand’s disease in 33-year-old patient. Comorbidity require specific types of the disease, taking into account the peculiarities of its course, monitoring ...
I. A. Grishechkina, T. V. Polomoshnova
doaj +1 more source
CONTEXT Air pollution is a risk factor for cardiovascular diseases (CVD), but the underlying biological mechanisms are not well understood. OBJECTIVE To determine whether markers related to CVD pathophysiological pathways (biomarkers for systemic ...
D. Rich+15 more
semanticscholar +1 more source
Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri+8 more
wiley +1 more source
Suppressing nonsense--a surprising function for 5-azacytidine. [PDF]
In this issue of EMBO Molecular Medicine, Bhuvanagiri et al report on a chemical means to convert molecular junk into gold. They identify a chemical inhibitor of a quality control pathway that is best known for its ability to clear cells of rubbish, but ...
Shao, Ada, Wilkinson, Miles F
core +2 more sources
Abstract Objectives Limited literature exists on non‐clinically significant varices (nCSV) and progression in children with portal hypertension (PHT). This study investigates trends and associations in this cohort. Methods This retrospective cohort study analysed 70 children with nCSV undergoing surveillance endoscopy between January 2012 and 2024 ...
Cody Chan+6 more
wiley +1 more source
THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS
Chronic glomerulonephritis remains the leading cause of formation of chronic renal insufficiency, which creates the necessity of looking for new ways of the progress impediment.
T.V. Margieva, T.V. Sergeeva
doaj +2 more sources
Objective: To compare the status of oral hygiene and dentition in patients with congenital hemorrhagic disorders with their age-matched healthy counterparts.
Mathangi Kumar+3 more
doaj
Flow-driven assembly of VWF fibres and webs in in vitro microvessels
Several systemic diseases, including thrombotic thrombocytopenic purpura, manifest much of their pathology through activation of endothelium and thrombotic occlusion of small blood vessels, often leading to multi-organ failure and death.
Ying Zheng, Junmei Chen, José A López
semanticscholar +1 more source
Von willebrand disease: An overview
Most commonly inherited bleeding disorder, first described in Aland Islands by Erik von Willebrand. It occurs as a result of decrease in plasma levels or defect in von Willebrand factor which is a large multimeric glycoprotein. Monomers of this glycoprotein undergo N-glycosylation to form dimers which get arranged to give multimers. Binding with plasma
K Pavani Bharati, U Ram Prashanth
openaire +4 more sources