Results 111 to 120 of about 58,549 (319)

Preoperative Atrial Fibrillation Does Not Impact Long‐Term Survival and Complications in Left Ventricular Assistance Device Recipients

Artificial Organs, EarlyView.
In this large multicenter study, AF before LVAD implantation was not associated with increased risks of mortality, bleeding, stroke, or pump thrombosis, but was linked to a higher incidence of late VAs. ABSTRACT Introduction A substantial proportion of patients receiving left ventricular assist devices (LVADs) present with pre‐existing atrial ...
Miloud Cherbi, Vincent Galand, Valentin Barré, Pierre Groussin, Melvyn Dezecot, Paul Gautier, Philippe Maury, Clément Delmas, Erwan Flecher, Raphael Martins   +9 more
wiley   +1 more source

Hemodynamic activation of von Willebrand factor in children with congenital heart diseases

Акушерство, гинекология и репродукция
Quite complex and non-linear cellular and molecular mechanisms underlie hemostasis changes in patients with congenital heart diseases (CHD). Altered activity ratio between von Willebrand factor (vWF) and metalloproteinase ADAMTS-13 (a disintegrin and ...
K. A. Tokmakova, D. N. Shilkin, A. A. Kupryashov   +2 more
doaj   +1 more source

A first description of the Colombian national registry for rare diseases

BMC Research Notes, 2017
Objective Orphan diseases must be considered a public health concern, underlying country-specific challenges for their accurate and opportune diagnosis, classification and management.
Heidi Eliana Mateus, Ana María Pérez, Martha Lucía Mesa, Germán Escobar, Jubby Marcela Gálvez, José Ivo Montaño, Martha Lucía Ospina, Paul Laissue   +7 more
doaj   +1 more source

Correction by factor VIII of the impaired platelet adhesion to subendothelium in von Willebrand disease [PDF]

, 1978
HJ Weiss, HR Baumgartner, T. Tschopp, VT Turitto, D Cohen   +4 more
openalex   +1 more source

Neurofilament light chain as a marker of peripheral nerve damage in vasculitic neuropathy? A cross‐compartmental correlation analysis in patients undergoing nerve biopsy

Brain Pathology, EarlyView.
To assess neurofilament light chain (NfL) as a biomarker of peripheral nerve damage, we correlated serumNfL concentrations with histopathological parameters from matched sural nerve biopsies. SerumNfL levels correlated with markers of acute axonal degeneration, but not with parameters reflecting chronic axonal loss.
Simon Streit, Jenny Meinhardt, Niclas Gimber, John Kestenbach, Christin Siewert, Jan Schmoranzer, Christian Meisel, Klemens Ruprecht, Frank L. Heppner, Péter Körtvélyessy, Werner Stenzel   +10 more
wiley   +1 more source

Increased von Willebrand Factor and Defective Ristocetin-Induced platelet Aggregation in Liver Disease [PDF]

, 1977
S Maragall, Antonio Ordinas, Carmine Clemente, F Casals, J. Profitós, R. Castillo   +5 more
openalex   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Clinical utility of panel-based genetic sequencing for von Willebrand disease

Research and Practice in Thrombosis and Haemostasis
Background: von Willebrand disease (VWD) is the most prevalent inherited bleeding disorder with a wide spectrum of causative variants. Next-generation sequencing analyzes the entire VWF gene and provides concomitant assessment of other genes, allowing ...
Radha Ramanan, Christine Van Laer, Sarissa Baert, Cyrielle Kint, Chris Van Geet, Quentin Van Thillo, Peter Verhamme, Thomas Vanassche, James D. McFadyen, Andrew C. Perkins, Huyen A. Tran, Veerle Labarque, Kathleen Freson   +12 more
doaj   +1 more source

Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders

Clinical Genetics, EarlyView.
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs, Neelam Giri, Marena R. Niewisch, Sharon A. Savage   +3 more
wiley   +1 more source

Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin. [PDF]

, 1987
Scott D. Berkowitz, J Dent, James R. Roberts, Yoshihiro Fujimura, EF Plow, Koiti Titani, Zaverio M. Ruggeri, T S Zimmerman   +7 more
openalex   +1 more source