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Artificial Organs, EarlyView.In this large multicenter study, AF before LVAD implantation was not associated with increased risks of mortality, bleeding, stroke, or pump thrombosis, but was linked to a higher incidence of late VAs. ABSTRACT Introduction A substantial proportion of patients receiving left ventricular assist devices (LVADs) present with pre‐existing atrial ...
Miloud Cherbi +9 more
wiley +1 more source
Clinical utility of panel-based genetic sequencing for von Willebrand disease
Research and Practice in Thrombosis and HaemostasisBackground: von Willebrand disease (VWD) is the most prevalent inherited bleeding disorder with a wide spectrum of causative variants. Next-generation sequencing analyzes the entire VWF gene and provides concomitant assessment of other genes, allowing ...
Radha Ramanan +12 more
doaj +1 more source
Artificial Organs, EarlyView.Aspirin discontinuation in long‐term, stable Heart Mate 3 LVAD patients maintained on Vitamin K antagonists did not increase hemocompatibility‐related adverse events. These findings support the safety of simplified antithrombotic therapy and extend randomized evidence for aspirin avoidance to the long‐term management of Heart Mate 3 recipients ...
Melanie Arnreiter +8 more
wiley +1 more source
A first description of the Colombian national registry for rare diseases
BMC Research Notes, 2017 Objective Orphan diseases must be considered a public health concern, underlying country-specific challenges for their accurate and opportune diagnosis, classification and management.
Heidi Eliana Mateus +7 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan +3 more
wiley +1 more source
Artificial Organs, EarlyView.Multicenter real‐world cohort (n = 327) comparing LVADs: HeartMate 3 (HM3), HeartMate II (HMII), and HeartWare (HVAD). HM3 showed superior long‐term survival versus legacy devices, driven by fewer hemocompatibility‐related adverse events, especially pump thrombosis and ischemic stroke, while major bleeding was similar across devices.
Hamza H. H. Ben Nasir +9 more
wiley +1 more source
Artificial Organs, EarlyView.Graphical summary of the experimental comparison of shear‐induced hemolysis in pediatric and adult blood using a Couette shearing device. Pediatric blood shows a trend toward lower increase in hemolysis at higher shear stress amplitudes, while no relevant differences are observed at low and intermediate stresses.
Vera Froese +4 more
wiley +1 more source
Bleeding Disorders in Children With Genetic Diseases: A Narrative Review
Acta Paediatrica, EarlyView.ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol +6 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs +17 more
wiley +1 more source