Results 111 to 120 of about 6,412,465 (299)

The Impact of Heavy Menstrual Bleeding on Quality of Life: A Mixed‐Methods Survey Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the physical, psychological, social, and functional impact of heavy menstrual bleeding (HMB) using a mixed‐methods approach. Design Mixed‐methods online survey. Population A UK‐wide sample of adults assigned female at birth with lived experience of HMB.
Michalina Drejza, Lily S. Nicholson, Gabrielle Paquette, Mehar Chawla, Claire L. Vale, Ewelina Rogozińska, Ngawai Moss, Niccola Hutchinson‐Pascal, Bassel H. Al Wattar   +8 more
wiley   +1 more source

Hemophilia A and von Willebrand disease: parallel therapeutic advances in the most common inherited bleeding disorders

Haematologica
von Willebrand disease (VWD) and hemophilia A (HA) are the most common inherited bleeding disorders, caused by quantitative or qualitative defects of von Willebrand factor (VWF) and coagulation factor VIII (FVIII).
Omid Seidizadeh, Flora Peyvandi, Pier Mannuccio Mannucci   +2 more
doaj   +1 more source

Clinically relevant differences between assays for von Willebrand factor activity

, 2018
Essentials It is unclear whether there are differences between von Willebrand factor (VWF) activity assays. We compared the four most used VWF activity assays in 661 von Willebrand disease (VWD) patients.

core   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Prevalence of iron deficiency in patients with mild to moderate bleeding disorders and bleeding disorder of unknown cause

Research and Practice in Thrombosis and Haemostasis
Background: Iron deficiency (ID) and ID anemia (IDA) are often caused by chronic bleeding, especially heavy menstrual bleeding, and thus may occur at a high frequency in patients with mild to moderate bleeding disorders (MBDs).
Tim Dreier, Dino Mehic, Justin Oosterlee, Jasmin Rast, Alexandra Kaider, Helmuth Haslacher, Cihan Ay, Ingrid Pabinger, Johanna Gebhart   +8 more
doaj   +1 more source

Progettazione di test clinici per la diagnosi della malattia di Von Willebrand

, 2022
La malattia di von Willebrand è una patologia ereditaria che interessa il processo coagulativo del sangue. Attraverso un modello fisiologico e tecniche MBDoE, si cerca di ottimizzare i test clinici ora impiegati, per una corretta diagnosi della malattia.
Castaldello, Christopher
core  

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, EarlyView.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source

Congenital infiltrating lipoma of the upper limb in a patient with von Willebrand disease

, 2000
Infiltrating lipoma is a rare variety of lipoma, characterized by an infiltration of the adipose tissue of the muscles. Infiltrating lipomas are usually classified in two groups: intermuscular infiltrating lipoma and ...
España, A., Lasso Vázquez, José María, Álava, E. de, Bazán, A., Zudaire, M.I.   +4 more
core   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

"Relation of Factor VIII and IX Inhibitors with ABO Blood Groups in 150 Patients with Haemophilia A and B "

Iranian Journal of Allergy, Asthma and Immunology, 2006
Many investigations have proved relations between ABO blood groups with some diseases and factor VIII and von willebrand level in plasma. In this study we investigated a relation between ABO blood groups and factor VIII and IX inhibitors in 102 patients ...
Hassan Mansouri Torghabeh, Aliakbar Pourfathollah, Mahmood Mahmoodian Shooshtari, Zahra Rezaie Yazdi   +3 more
doaj