Results 131 to 140 of about 160,288 (338)

Hemodynamic activation of von Willebrand factor in children with congenital heart diseases

open access: yesАкушерство, гинекология и репродукция
Quite complex and non-linear cellular and molecular mechanisms underlie hemostasis changes in patients with congenital heart diseases (CHD). Altered activity ratio between von Willebrand factor (vWF) and metalloproteinase ADAMTS-13 (a disintegrin and ...
K. A. Tokmakova   +2 more
doaj   +1 more source

A first description of the Colombian national registry for rare diseases

open access: yesBMC Research Notes, 2017
Objective Orphan diseases must be considered a public health concern, underlying country-specific challenges for their accurate and opportune diagnosis, classification and management.
Heidi Eliana Mateus   +7 more
doaj   +1 more source

Laminar Flow Alters EV Composition in HUVECs: A Study of Culture Medium Optimization and Molecular Profiling of Vesicle Cargo

open access: yesSmall Methods, EarlyView.
Schematic illustration of the current study. A) Multiple cell culture media are used for HUVEC cultures under both static and flow conditions. Cells are analyzed for morphology, endothelial markers, and gene expression. B) EVs are isolated from static and flow HUVEC cultures, and investigated for particle characterization, transcriptome and proteome ...
Arefeh Kardani   +13 more
wiley   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu   +6 more
wiley   +1 more source

Inherited Bleeding Disorders in Iraq and Consanguineous Marriage

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2018
Background: Consanguineous marriage is defined as inbreeding between second cousins or closer. In such families there will be a potential increase in the autosomal recessive traits with its lethal effect, with an increased risk of morbidity and mortality
Nidal Karim Al-Rahal
doaj   +1 more source

Correction by factor VIII of the impaired platelet adhesion to subendothelium in von Willebrand disease [PDF]

open access: bronze, 1978
HJ Weiss   +4 more
openalex   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini   +10 more
wiley   +1 more source

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