Hemodynamic activation of von Willebrand factor in children with congenital heart diseases
Quite complex and non-linear cellular and molecular mechanisms underlie hemostasis changes in patients with congenital heart diseases (CHD). Altered activity ratio between von Willebrand factor (vWF) and metalloproteinase ADAMTS-13 (a disintegrin and ...
K. A. Tokmakova+2 more
doaj +1 more source
A first description of the Colombian national registry for rare diseases
Objective Orphan diseases must be considered a public health concern, underlying country-specific challenges for their accurate and opportune diagnosis, classification and management.
Heidi Eliana Mateus+7 more
doaj +1 more source
Stabilization of the Antihemophilic Factor (VIII :AHF) by the Von Willebrand Factor (VIII :VWF): A Possible Model for Von Willebrand’s Disease [PDF]
Harvey J. Weiss+2 more
openalex +1 more source
Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis
ESC Heart Failure, EarlyView.
Jiayu Liang, Suxin Luo, Bi Huang
wiley +1 more source
Schematic illustration of the current study. A) Multiple cell culture media are used for HUVEC cultures under both static and flow conditions. Cells are analyzed for morphology, endothelial markers, and gene expression. B) EVs are isolated from static and flow HUVEC cultures, and investigated for particle characterization, transcriptome and proteome ...
Arefeh Kardani+13 more
wiley +1 more source
Platelet factor VIII-related antigen: studies in vivo after transfusion in patients with von Willebrand disease [PDF]
Y Sultan+4 more
openalex +1 more source
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n
Lichieh Julie Chu+6 more
wiley +1 more source
Inherited Bleeding Disorders in Iraq and Consanguineous Marriage
Background: Consanguineous marriage is defined as inbreeding between second cousins or closer. In such families there will be a potential increase in the autosomal recessive traits with its lethal effect, with an increased risk of morbidity and mortality
Nidal Karim Al-Rahal
doaj +1 more source
Correction by factor VIII of the impaired platelet adhesion to subendothelium in von Willebrand disease [PDF]
HJ Weiss+4 more
openalex +1 more source
Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini+10 more
wiley +1 more source