Results 11 to 20 of about 160,288 (338)

Acquired von Willebrand syndrome: focused for hematologists

Haematologica, 2020
The acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. However, unlike the inherited disease, AvWS occurs in persons with no personal and family history of ...
Massimo Franchini, Pier Mannuccio Mannucci   +1 more
doaj   +2 more sources

Intraindividual variability of von Willebrand factor and the need for repeated testing [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Diagnosing von Willebrand disease (VWD) is complicated by intraindividual variation of von Willebrand factor (VWF). Current guidelines define VWD as VWF antigen (VWF:Ag) or VWF activity of
Malene Helligsø Kirkeby, Johanne Andersen Højbjerg, Anders Mønsted Abildgaard, Julie Brogaard Larsen   +3 more
doaj   +2 more sources

Diagnosis of platelet-type von Willebrand disease by flow cytometry

Haematologica, 2010
Platelet-type von Willebrand disease (PT-VWD) is a rare autosomal dominant bleeding disorder which is due to a mutation in the gene encoding for platelet glycoprotein Ibα (GPIbα) resulting in enhanced affinity for von Willebrand factor (VWF).
Silvia Giannini, Luca Cecchetti, Anna Maria Mezzasoma, Paolo Gresele   +3 more
doaj   +2 more sources

Oral post-surgical complications in patients with hemophilia and von Willebrand disease [PDF]

Hematology, Transfusion and Cell Therapy
Objective: To determine the prevalence of post-surgical complications in patients with hemophilia and von Willebrand disease. Methods: A prospective, cross-sectional study with descriptive and exploratory data analysis was conducted at the outpatient ...
Luisa Catarina Porfirio de Sousa, Elanne Cristina Garcia da Costa Félix, Wagner Hespanhol, Raquel dos Santos Pinheiro   +3 more
doaj   +2 more sources

Clinical utility of panel-based genetic sequencing for von Willebrand disease [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: von Willebrand disease (VWD) is the most prevalent inherited bleeding disorder with a wide spectrum of causative variants. Next-generation sequencing analyzes the entire VWF gene and provides concomitant assessment of other genes, allowing ...
Radha Ramanan, Christine Van Laer, Sarissa Baert, Cyrielle Kint, Chris Van Geet, Quentin Van Thillo, Peter Verhamme, Thomas Vanassche, James D. McFadyen, Andrew C. Perkins, Huyen A. Tran, Veerle Labarque, Kathleen Freson   +12 more
doaj   +2 more sources

von Willebrand Disease

Medicine, 1997
Considerable progress has been made in characterizing the specific molecular defects responsible for the heterogeneous disorder known as von Willebrand disease (VWD). A large number of molecular defects have been identified and precise characterization may now be possible in the majority of type 2A, type 2B, type 2N, and potentially also type 3 VWD ...
William C. Nichols, David Ginsburg
openalex   +3 more sources

Case report: A case of acquired von Willebrand syndrome as onset clinical presentation of systemic lupus erythematosus manifested as epistaxis and pulmonary hemorrhage

Frontiers in Pediatrics, 2022
BackgroundAcquired von Willebrand syndrome (AVWS) is a less common bleeding disorder, primarily manifested as mild to moderate mucocutaneous bleeding and laboratory tests are similar to hereditary von Willebrand disease (VWD).
Songmi Wang, Qun Hu, Yaxian Chen, Xiufen Hu, Ning Tang, Ai Zhang, Aiguo Liu   +6 more
doaj   +1 more source

Pseudotumor of the Maxillary Sinus in a Child with Von Willebrand Disease [PDF]

Iranian Journal of Otorhinolaryngology, 2022
Introduction:Mandibular pseudotumors, also known as blood cysts, are rare complications which occur more frequently in patients with an associated bleeding disorder such as hemophilia.Case Report: We present a case of a 2-year and 6-month-old patient ...
Martha Gutierrez Perez, Juan Lugo Machado, Natalia Barreto Nino, Luis Paredes Bastos, David Acevedo Contreras   +4 more
doaj   +1 more source

Rictor maintains endothelial integrity under shear stress

Frontiers in Cell and Developmental Biology, 2022
Background: Endothelial injury induced by low shear stress (LSS) is an initiating factor in the pathogenesis of various cardiovascular diseases, including atherosclerosis, hypertension, and thrombotic diseases.
Hui Li, Wen-Ying Zhou, Yi-Xian Liu, Yi-Yuan Xia, Chun-Lei Xia, Dao-Rong Pan, Zheng Li, Yi Shi, Shao-Liang Chen, Jun-Xia Zhang   +9 more
doaj   +1 more source

Von Willebrand disease

Hematology, 2014
Von Willebrand disease (VWD) is an inherited defect of blood coagulation that may cause excessive bleeding.
Stacy Cooper, Clifford M. Takemoto
  +8 more sources