Results 41 to 50 of about 147,268 (335)
Comprehensive Analyses of Coagulation Parameters in Patients with Vascular Anomalies
Background: Vascular anomalies comprise a diverse group of rare diseases with altered blood flow and are often associated with coagulation disorders. The most common example is a localized intravascular coagulopathy in venous malformations leading to ...
Friedrich G. Kapp +6 more
doaj +1 more source
Extracorporeal membrane oxygenation (ECMO) is an increasingly acceptable life-saving mechanical assistance system that provides cardiac and/or respiratory support for several reversible or treatable diseases.
Haiwang Wang +23 more
doaj +1 more source
Changes of von Willebrand Factor during Pregnancy in Women with and without von Willebrand Disease
Delivery in von Willebrand disease (VWD) represents a significant hemostatic challenge because of the variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF.
G. Castaman
semanticscholar +1 more source
On the Versatility of von Willebrand Factor
Von Willebrand factor (VWF) is a large multimeric protein, the function of which has been demonstrated to be pivotal to the haemostatic system. Indeed, quantitative and/or qualitative abnormalities of VWF are associated with the bleeding disorder Von ...
A. Rauch +5 more
semanticscholar +1 more source
Acquired von Willebrand syndrome following a SARS-CoV2 infection.
Acquired von Willebrand syndrome is a rare entity with approximately 700 cases described in the literature. Many etiologies are responsible for this condition, mainly lymphoproliferative and myeloproliferative syndromes, as well as cardiac diseases ...
Michael Iarossi +3 more
core +1 more source
Aptamer-based applications for cardiovascular disease
Cardiovascular disease (especially atherosclerosis) is a major cause of death worldwide, and novel diagnostic tools and treatments for this disease are urgently needed. Aptamers are single-stranded oligonucleotides that specifically recognize and bind to
Xinyuan Chen, Yue Ma, Yuquan Xie, Jun Pu
doaj +1 more source
Background Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with exocytosis of Weibel-Palade bodies (WPBs) may play an etiological role in this condition.
K. Djamiatun +8 more
semanticscholar +1 more source
Herbert Gritsch,1 Gerald Schrenk,1 Nina Weinhappl,1 Björn Mellgård,2 Bruce Ewenstein,2 Peter L Turecek3,4 1Pharmaceutical Sciences, Baxalta Innovations GmbH, a Takeda Company, Vienna, Austria; 2Rare Genetics and Hematology, Research & Development, Takeda
Gritsch H +5 more
doaj
Considerable progress has been made in characterizing the specific molecular defects responsible for the heterogeneous disorder known as von Willebrand disease (VWD). A large number of molecular defects have been identified and precise characterization may now be possible in the majority of type 2A, type 2B, type 2N, and potentially also type 3 VWD ...
W C, Nichols, D, Ginsburg
openaire +2 more sources
During the past 25 years, our knowledge concerning the pathogenesis, diagnostic strategies, and treatment of von Willebrand disease (VWD) has increased significantly.
Paula D. James, D. Lillicrap
semanticscholar +1 more source

