Results 41 to 50 of about 147,268 (335)

Comprehensive Analyses of Coagulation Parameters in Patients with Vascular Anomalies

open access: yesBiomolecules, 2022
Background: Vascular anomalies comprise a diverse group of rare diseases with altered blood flow and are often associated with coagulation disorders. The most common example is a localized intravascular coagulopathy in venous malformations leading to ...
Friedrich G. Kapp   +6 more
doaj   +1 more source

Shear-induced acquired von Willebrand syndrome: an accomplice of bleeding events in adults on extracorporeal membrane oxygenation support

open access: yesFrontiers in Cardiovascular Medicine, 2023
Extracorporeal membrane oxygenation (ECMO) is an increasingly acceptable life-saving mechanical assistance system that provides cardiac and/or respiratory support for several reversible or treatable diseases.
Haiwang Wang   +23 more
doaj   +1 more source

Changes of von Willebrand Factor during Pregnancy in Women with and without von Willebrand Disease

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2013
Delivery in von Willebrand disease (VWD) represents a significant hemostatic challenge because of the variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF.
G. Castaman
semanticscholar   +1 more source

On the Versatility of von Willebrand Factor

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2013
Von Willebrand factor (VWF) is a large multimeric protein, the function of which has been demonstrated to be pivotal to the haemostatic system. Indeed, quantitative and/or qualitative abnormalities of VWF are associated with the bleeding disorder Von ...
A. Rauch   +5 more
semanticscholar   +1 more source

Acquired von Willebrand syndrome following a SARS-CoV2 infection.

open access: yes, 2023
Acquired von Willebrand syndrome is a rare entity with approximately 700 cases described in the literature. Many etiologies are responsible for this condition, mainly lymphoproliferative and myeloproliferative syndromes, as well as cardiac diseases ...
Michael Iarossi   +3 more
core   +1 more source

Aptamer-based applications for cardiovascular disease

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Cardiovascular disease (especially atherosclerosis) is a major cause of death worldwide, and novel diagnostic tools and treatments for this disease are urgently needed. Aptamers are single-stranded oligonucleotides that specifically recognize and bind to
Xinyuan Chen, Yue Ma, Yuquan Xie, Jun Pu
doaj   +1 more source

Severe Dengue Is Associated with Consumption of von Willebrand Factor and Its Cleaving Enzyme ADAMTS-13

open access: yesPLoS Neglected Tropical Diseases, 2012
Background Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with exocytosis of Weibel-Palade bodies (WPBs) may play an etiological role in this condition.
K. Djamiatun   +8 more
semanticscholar   +1 more source

Structure and Function of Recombinant versus Plasma-Derived von Willebrand Factor and Impact on Multimer Pharmacokinetics in von Willebrand Disease

open access: yesJournal of Blood Medicine, 2022
Herbert Gritsch,1 Gerald Schrenk,1 Nina Weinhappl,1 Björn Mellgård,2 Bruce Ewenstein,2 Peter L Turecek3,4 1Pharmaceutical Sciences, Baxalta Innovations GmbH, a Takeda Company, Vienna, Austria; 2Rare Genetics and Hematology, Research & Development, Takeda
Gritsch H   +5 more
doaj  

von Willebrand Disease

open access: yesMedicine, 1997
Considerable progress has been made in characterizing the specific molecular defects responsible for the heterogeneous disorder known as von Willebrand disease (VWD). A large number of molecular defects have been identified and precise characterization may now be possible in the majority of type 2A, type 2B, type 2N, and potentially also type 3 VWD ...
W C, Nichols, D, Ginsburg
openaire   +2 more sources

von Willebrand Disease: Clinical and Laboratory Lessons Learned from the Large von Willebrand Disease Studies

open access: yesAmerican journal of hematology/oncology, 2012
During the past 25 years, our knowledge concerning the pathogenesis, diagnostic strategies, and treatment of von Willebrand disease (VWD) has increased significantly.
Paula D. James, D. Lillicrap
semanticscholar   +1 more source

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