Results 51 to 60 of about 147,268 (335)

Correlation of intracardiac hemodynamics indicators with von Willebrand factor – Marker of endothelial dysfunction in patients with coronary artery disease combined with coronavirus disease (COVID-19) [PDF]

Българска кардиология
The research relevance is predefined by the need to establish the relationship and identify new markers and potential contributions to clinical practice and scientific progress.
V. Netiazhenko, S. Mostovyi, O. Safonova
doaj   +3 more sources

Global Overview of Von Willebrand Disease Research: A Bibliometric Study

Journal of Applied Hematology
INTRODUCTION: Von Willebrand disease (VWD) is a hereditary bleeding disorder with a high global prevalence. The aim of this study is to analyze the global landscape of scientific production on VWD.
John Barja-Ore, Brandon Emerson Guillen-Calle, Jhony Jesus Chafloque Chavesta, Zaida Zagaceta Guevara, Sandra Muñoz-Huaracán, Guipsy Rebolledo-Aburto   +5 more
doaj   +1 more source

Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population

Biomedicines, 2022
Cardiovascular diseases are common in patients with chronic obstructive pulmonary disease (COPD). Clot formation and resolution secondary to systemic inflammation may be a part of the explanation.
Peter Kamstrup, Jannie Marie Bülow Sand, Charlotte Suppli Ulrik, Julie Janner, Christian Philip Rønn, Sarah Rank Rønnow, Diana Julie Leeming, Sidse Graff Jensen, Torgny Wilcke, Alexander G. Mathioudakis, Marc Miravitlles, Therese Lapperre, Elisabeth Bendstrup, Ruth Frikke-Schmidt, Daniel D. Murray, Theis Itenov, Apostolos Bossios, Susanne Dam Nielsen, Jørgen Vestbo, Tor Biering-Sørensen, Morten Karsdal, Jens-Ulrik Jensen, Pradeesh Sivapalan   +22 more
doaj   +1 more source

Treatment of Von Willebrand Disease [PDF]

Thrombosis and Haemostasis, 1998
SummaryIn von Willebrand disease, there are two main options for the treatment of spontaneous bleeding episodes and for bleeding prophylaxis: desmopressin and transfusional therapy with plasma products. Desmopressin is the treatment of choice for most patients with type 1, who account for approximately 70 to 80 per cent of all cases with the disease ...
C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, P. M. MANNUCCI   +5 more
openaire   +6 more sources

Acquired von Willebrand Syndrome Secondary to Normally Functioning Mechanical Aortic Valve and High-Output Cardiac State

Journal of Cardiovascular Development and Disease, 2022
Acquired von Willebrand syndrome (AVWS) is caused by an acquired deficiency of von Willebrand factor (VWF), a multimeric protein required for primary hemostasis. For patients with heart valve diseases, high gradient across the malfunctioning valves could
Xinglin Yang, Jinghong Zhang, Yamin Lai, Xuemin Yan, Xiaoxiao Guo, Jianhua Han, Jihai Liu, Jiangshan Wang, Huadong Zhu   +8 more
doaj   +1 more source

An apparently silent nucleotide substitution (c.7056C>T) in the von Willebrand factor gene is responsible for type 1 von Willebrand disease

Haematologica, 2011
Background Nucleotide variations not changing protein sequences are considered silent mutations; accumulating data suggest that they can, however, be important in human diseases.
V. Daidone, L. Gallinaro, Maria Grazia Cattini, E. Pontara, A. Bertomoro, A. Pagnan, A. Casonato   +6 more
semanticscholar   +1 more source

Intraindividual variability of von Willebrand factor and the need for repeated testing

Research and Practice in Thrombosis and Haemostasis
Background: Diagnosing von Willebrand disease (VWD) is complicated by intraindividual variation of von Willebrand factor (VWF). Current guidelines define VWD as VWF antigen (VWF:Ag) or VWF activity of
Malene Helligsø Kirkeby, Johanne Andersen Højbjerg, Anders Mønsted Abildgaard, Julie Brogaard Larsen   +3 more
doaj   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure.

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Hársfalvi, Jolán, Gombos, Tímea, Cervenak, László, Jánoskuti, Lívia, Förhécz, Zsolt, Prohászka, Zoltán, Papassotiriou, Jana, Makó, Veronika, Pozsonyi, Zoltán, Kunde, Jan   +10 more
core   +1 more source

Review Dental Treatment of Patients with Congenital Bleeding Disorders

Česká Stomatologie a Praktické Zubní Lékařství, 2014
Objectives: The commonest congenital bleeding disorders in childhood are hemophilia, von Willebrand disease and deficiency of factor XI. Disease is characterized by a deficient of coagulability. It is a gonosomal recessive condition.
J. Papež, K. Chleborád, T. Dostálová
doaj   +1 more source

Lower levels of vWF are associated with lower risk of cardiovascular disease

Research and Practice in Thrombosis and Haemostasis, 2022
Objective The current study was undertaken to prospectively explore whether having low levels of von Willebrand factor (vWF) antigen and vWF activity reduce the risk for cardiovascular disease and death. Methods VWF antigen and vWF activity were measured
Pauline C. S. vanParidon, Marina Panova‐Noeva, Rene vanOerle, Andreas Schulz, Jürgen H. Prochaska, Natalie Arnold, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Karl J. Lackner, Hugo tenCate, Philipp S. Wild, Henri M. H. Spronk   +13 more
doaj   +1 more source