Results 31 to 40 of about 6,412,465 (299)

Novel therapies for von Willebrand disease. [PDF]

Blood Adv
International audienceAbstract For the past decades, treatment for von Willebrand disease has essentially consisted of classic approaches, and only in the past few years has the need for more innovative strategies been recognized. To address the needs of
Denis CV, Dich H, Casari C.
europepmc   +2 more sources

Treatment of Von Willebrand Disease [PDF]

Thrombosis and Haemostasis, 1998
SummaryIn von Willebrand disease, there are two main options for the treatment of spontaneous bleeding episodes and for bleeding prophylaxis: desmopressin and transfusional therapy with plasma products. Desmopressin is the treatment of choice for most patients with type 1, who account for approximately 70 to 80 per cent of all cases with the disease ...
C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, P. M. MANNUCCI   +5 more
openaire   +6 more sources

A preliminary analysis of platelet von willebrand factor oligosaccharides [PDF]

, 2000
2000-05Little is known about the carbohydrate structure of the platelet von Willebrand factor (vWf). We have analyzed N-linked oligosaccharides from both plasma and platelet vWf by Fluorophore-Assisted-Carbohydrate Electrophoresis (FACE.) and isoelectric
Horne, McDonald, Kagami, Kazuo, Gralnick, Harvey, Williams, Sybil   +3 more
core   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, EarlyView.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources

Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population

Biomedicines, 2022
Cardiovascular diseases are common in patients with chronic obstructive pulmonary disease (COPD). Clot formation and resolution secondary to systemic inflammation may be a part of the explanation.
Peter Kamstrup, Jannie Marie Bülow Sand, Charlotte Suppli Ulrik, Julie Janner, Christian Philip Rønn, Sarah Rank Rønnow, Diana Julie Leeming, Sidse Graff Jensen, Torgny Wilcke, Alexander G. Mathioudakis, Marc Miravitlles, Therese Lapperre, Elisabeth Bendstrup, Ruth Frikke-Schmidt, Daniel D. Murray, Theis Itenov, Apostolos Bossios, Susanne Dam Nielsen, Jørgen Vestbo, Tor Biering-Sørensen, Morten Karsdal, Jens-Ulrik Jensen, Pradeesh Sivapalan   +22 more
doaj   +1 more source

Intraindividual variability of von Willebrand factor and the need for repeated testing

Research and Practice in Thrombosis and Haemostasis
Background: Diagnosing von Willebrand disease (VWD) is complicated by intraindividual variation of von Willebrand factor (VWF). Current guidelines define VWD as VWF antigen (VWF:Ag) or VWF activity of
Malene Helligsø Kirkeby, Johanne Andersen Højbjerg, Anders Mønsted Abildgaard, Julie Brogaard Larsen   +3 more
doaj   +1 more source

Acquired von Willebrand Syndrome Secondary to Normally Functioning Mechanical Aortic Valve and High-Output Cardiac State

Journal of Cardiovascular Development and Disease, 2022
Acquired von Willebrand syndrome (AVWS) is caused by an acquired deficiency of von Willebrand factor (VWF), a multimeric protein required for primary hemostasis. For patients with heart valve diseases, high gradient across the malfunctioning valves could
Xinglin Yang, Jinghong Zhang, Yamin Lai, Xuemin Yan, Xiaoxiao Guo, Jianhua Han, Jihai Liu, Jiangshan Wang, Huadong Zhu   +8 more
doaj   +1 more source

Fifth Åland Island conference on von Willebrand disease [PDF]

, 2018
The fifth Åland Island meeting on von Willebrand disease (VWD) was held on the Åland Islands, Finland, from 22 to 24 September 2016 – 90 years after the first case of VWD was diagnosed in a patient from the Åland Islands in 1926.
Windyga, J, Goudemand, J, Aledort, L., Mourik, M, T. Szántó, Blombäck, M., Cnossen, M H, Mannucci, PM, Berntorp, E., Goudemand J., Berntorp, E, von Depka M., E. Berntorp, Federici, A.B., J. Goudemand, Ågren, A, Onundarson P. T., Aledort L., Szanto T., Berntorp E., Mourik M., Mannucci, P. M., Goodeve, A, Windyga, J., Önundarson, P. T., Mannucci, P M, J. Windyga, Croteau, S.E., Onundarson, PT, Federici A. B., Aledort, L, M. von Depka, P. T. Önundarson, S. E. Croteau, Mannucci, P.M., Rodeghiero, F., A. B. Federici, M. Mourik, Croteau, SE, F. Rodeghiero, Goodeve A., Önundarson, P.T., Croteau, S E, Blomback M., Mannucci P. M., Ågren, A., Cnossen, M. H., M. H. Cnossen, Agren A., Rodeghiero F., A. Goodeve, von Depka, M, M. Blombäck, Goodeve, A., Croteau, S. E., Cnossen M. H., Szántó, T., Rodeghiero, F, A. Ågren, Goudemand, J., Federici, A. B., Cnossen, M.H., P. M. Mannucci, Cnossen, Marjon, Federici, A B, Szántó, T, Mourik, M., Federici, AB, Windyga J., von Depka, M., Blombäck, M, L. Aledort, Croteau S. E., Önundarson, P T   +73 more
core   +1 more source

Review Dental Treatment of Patients with Congenital Bleeding Disorders

Česká Stomatologie a Praktické Zubní Lékařství, 2014
Objectives: The commonest congenital bleeding disorders in childhood are hemophilia, von Willebrand disease and deficiency of factor XI. Disease is characterized by a deficient of coagulability. It is a gonosomal recessive condition.
J. Papež, K. Chleborád, T. Dostálová
doaj   +1 more source

Lower levels of vWF are associated with lower risk of cardiovascular disease

Research and Practice in Thrombosis and Haemostasis, 2022
Objective The current study was undertaken to prospectively explore whether having low levels of von Willebrand factor (vWF) antigen and vWF activity reduce the risk for cardiovascular disease and death. Methods VWF antigen and vWF activity were measured
Pauline C. S. vanParidon, Marina Panova‐Noeva, Rene vanOerle, Andreas Schulz, Jürgen H. Prochaska, Natalie Arnold, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Karl J. Lackner, Hugo tenCate, Philipp S. Wild, Henri M. H. Spronk   +13 more
doaj   +1 more source